[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616829":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":19,"locations":28,"responsibleParty":164,"collaborators":166,"id":170,"slug":171,"hasResults":172,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":176,"eligibilityCriteria":177,"healthyVolunteers":172,"sex":178,"minAge":179,"maxAge":10,"enrollmentInfo":180,"targetDuration":183,"studyType":184,"phases":10,"briefSummary":185,"conditions":186,"keywords":189,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":204},{"fullName":5,"class":6},"Infanta Leonor University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Prospective VTE Cohort",null,"Adults with objectively confirmed symptomatic venous thromboembolism (deep vein thrombosis and\u002For pulmonary embolism) consecutively enrolled from December 2025 to December 2027 in participating hospitals. All participants will undergo routine clinical evaluation, laboratory testing, and cancer screening according to standard practice. The CLOVER score will be calculated at baseline using the web-based tool (CLOVER-Web).",[13,17],{"name":14,"affiliation":15,"role":16},"Anabel Franco-Moreno, MD, PhD","Hospital Universitario Infanta Leonor","PRINCIPAL_INVESTIGATOR",{"name":18,"affiliation":15,"role":16},"Franco-Moreno, MD, PhD",[20,25],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Anabel Franco Moreno, MD, PhD","CONTACT","+34686102661","afranco278@hotmail.com",{"name":26,"role":22,"phone":27,"phoneExt":10,"email":24},"Anabel Franco Moreno","MD, PhD",[29,46,57,67,77,87,97,110,120,134,146,155],{"facility":30,"status":31,"city":32,"state":32,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Hospital Clínic","RECRUITING","Barcelona","Spain","ES",{"type":36,"coordinates":37},"Point",[38,39],2.15899,41.38879,{"lat":39,"lon":38},[42],{"name":43,"role":22,"phone":44,"phoneExt":10,"email":45},"JESUS AIBAR, MD, PhD","932 27 54 00","JAIBAR@clinic.cat",{"facility":15,"status":31,"city":47,"state":47,"zip":48,"country":33,"countryCode":34,"cosmosGeoPoint":49,"geoPoint":53,"contacts":54},"Madrid","28051",{"type":36,"coordinates":50},[51,52],-3.70256,40.4165,{"lat":52,"lon":51},[55],{"name":21,"role":22,"phone":56,"phoneExt":10,"email":24},"686102661",{"facility":58,"status":31,"city":47,"state":47,"zip":48,"country":33,"countryCode":34,"cosmosGeoPoint":59,"geoPoint":61,"contacts":62},"Hospital Universitario La Paz",{"type":36,"coordinates":60},[51,52],{"lat":52,"lon":51},[63],{"name":64,"role":22,"phone":65,"phoneExt":10,"email":66},"Teresa Sancho, MD","917 27 70 00","tsbueso@gmail.com",{"facility":68,"status":31,"city":47,"state":47,"zip":48,"country":33,"countryCode":34,"cosmosGeoPoint":69,"geoPoint":71,"contacts":72},"Hospital Universitario Príncipe de Asturias",{"type":36,"coordinates":70},[51,52],{"lat":52,"lon":51},[73],{"name":74,"role":22,"phone":75,"phoneExt":10,"email":76},"f garcia sanchez, MD","91 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Arrixaca","Murcia",{"type":36,"coordinates":101},[102,103],-1.13004,37.98704,{"lat":103,"lon":102},[106],{"name":107,"role":22,"phone":108,"phoneExt":10,"email":109},"Leticia Guirado Torrecillas, MD","968 36 95 00","leticia.guiradotorrecillas@gmail.com",{"facility":111,"status":31,"city":99,"state":99,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":112,"geoPoint":114,"contacts":115},"Hospital Universitario Morales Meseguer",{"type":36,"coordinates":113},[102,103],{"lat":103,"lon":102},[116],{"name":117,"role":22,"phone":118,"phoneExt":10,"email":119},"Javier Pagán, MD, PhD","968 36 09 00","pagan02468@gmail.com",{"facility":121,"status":31,"city":122,"state":123,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":124,"geoPoint":128,"contacts":129},"Hospital San Agustín","Avilés","Principality of Asturias",{"type":36,"coordinates":125},[126,127],-5.92483,43.55473,{"lat":127,"lon":126},[130],{"name":131,"role":22,"phone":132,"phoneExt":10,"email":133},"José Ferreiro Celeiro, MD","985 12 30 00","jcaussie@hotmail.com",{"facility":135,"status":31,"city":136,"state":10,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":137,"geoPoint":141,"contacts":142},"Hospital Universitario Son Llatzer","Balea",{"type":36,"coordinates":138},[139,140],-8.79484,42.2531,{"lat":140,"lon":139},[143],{"name":144,"role":22,"phone":10,"phoneExt":10,"email":145},"Elena Cisneros de la Fuente, MD","ecisneros@hsll.es",{"facility":147,"status":31,"city":47,"state":10,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":148,"geoPoint":150,"contacts":151},"Hospital Universitario 12 de Octubre",{"type":36,"coordinates":149},[51,52],{"lat":52,"lon":51},[152],{"name":153,"role":22,"phone":10,"phoneExt":10,"email":154},"Jose Bascuñana Morejon de Giron, MD, PhD","josebascumor@gmail.com",{"facility":156,"status":31,"city":47,"state":10,"zip":10,"country":33,"countryCode":34,"cosmosGeoPoint":157,"geoPoint":159,"contacts":160},"Hospital Universitario de Fuenlabrada",{"type":36,"coordinates":158},[51,52],{"lat":52,"lon":51},[161],{"name":162,"role":22,"phone":10,"phoneExt":10,"email":163},"Cristina De Ancos Aracil, MD","drcancos@gmail.com",{"type":16,"investigatorFullName":26,"investigatorTitle":165,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Specialist in Internal Medicine",[167],{"name":168,"class":169},"Fundación para la Investigación e Innovación Biomédica del Hospital Universitario Infanta Leonor","UNKNOWN","100616829","external-validation-of-the-clover-score-for-detecting-occult-cancer-in-venous-thromboembolism-patients-100616829",false,"NCT07310693","External Validation of the CLOVER Score for Detecting Occult Cancer in Venous Thromboembolism Patients","External Validation of a Predictive Model for Occult Cancer Risk in Patients With Venous Thromboembolism Developed Using Machine Learning","CLOVER","Inclusion Criteria:\n\n* Age ≥18 years.\n* Objectively confirmed acute symptomatic venous thromboembolism (deep vein thrombosis and\u002For pulmonary embolism).\n* Ability to provide written or electronic informed consent.\n\nExclusion Criteria:\n\n* Suspicion of cancer during the initial diagnostic evaluation for VTE.\n* Participation in another interventional study that may interfere with outcomes.\n* Inability or refusal to provide informed consent.","ALL","18 Years",{"count":181,"type":182},500,"ESTIMATED","2 Years","OBSERVATIONAL","This study aims to externally validate the CLOVER score, a machine learning-based predictive model designed to identify patients with venous thromboembolism (VTE) who are at increased risk of having an occult cancer. The study includes a retrospective cohort of patients with acute symptomatic VTE diagnosed between 2000 and 2022, and a prospective cohort of consecutively recruited patients from December 2025 to December 2027. The CLOVER model will be applied to all participants, and its ability to discriminate between patients with and without occult cancer will be evaluated. The study also assesses clinicians' satisfaction with the web-based tool (CLOVER-Web) developed to facilitate the use of the score in clinical practice.",[187,188],"Venous Thromboembolism (VTE)","Occult Cancer",[188,190,191,192,193,194],"Venous thromboembolism","Machine learning","Prediction model","External validation","CLOVER score","2025-12-20",{"date":197,"type":198},"2025-12-30","ACTUAL",{"date":200,"type":198},"2025-12-01",{"date":202,"type":182},"2028-12-31",{"name":5,"class":6},12]