[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100620511":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":31,"collaborators":7,"id":33,"slug":34,"hasResults":35,"nctId":36,"briefTitle":37,"officialTitle":38,"acronym":7,"eligibilityCriteria":39,"healthyVolunteers":35,"sex":40,"minAge":41,"maxAge":42,"enrollmentInfo":43,"targetDuration":46,"studyType":47,"phases":7,"briefSummary":48,"conditions":49,"keywords":51,"overallStatus":17,"whyStopped":7,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},{"fullName":5,"class":6},"Beijing Friendship Hospital","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Hao Wang","CONTACT","+86 18810643768","wanghao4756@163.com",[15],{"facility":16,"status":17,"city":18,"state":19,"zip":20,"country":21,"countryCode":22,"cosmosGeoPoint":23,"geoPoint":28,"contacts":29},"Beijing Friendship Hospital, Capital Medical University","RECRUITING","Beijing","Beijing Municipality","100050","China","CN",{"type":24,"coordinates":25},"Point",[26,27],116.39723,39.9075,{"lat":27,"lon":26},[30],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},{"type":32,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100620511","eye-brain-kidney-in-ckd-100620511",false,"NCT07358572","Eye-Brain-Kidney in CKD","A Study on the Eye-Brain-Kidney Interaction Mechanisms in Chronic Kidney Disease Based on Multimodal Magnetic Resonance Imaging","Inclusion Criteria:\n\n1. Aged 18-70 years.\n2. Patients clinically diagnosed with CKD stages 1-5.\n3. No contraindications for MRI examination (e.g., cardiac pacemaker, claustrophobia, cochlear implant, hearing aid, coronary stents implanted before 2015) and able to complete the MRI scan.\n\nExclusion Criteria:\n\n1. Patients with recent or prior cerebral hemorrhage or cerebral infarction.\n2. History of epileptic seizures or psychiatric disorders.\n3. Patients with claustrophobia.\n4. Pregnant or lactating patients.\n5. Presence of other central nervous system diseases (e.g., tumor, trauma).\n6. Unstable angina, congestive heart failure (NYHA class III or IV), or acute myocardial infarction.\n7. Any systemic or other diseases deemed unsuitable for clinical trial participation.","ALL","18 Years","70 Years",{"count":44,"type":45},1500,"ESTIMATED","3 Years","OBSERVATIONAL","The goal of this observational study is to learn about the interaction between the eyes, brain, and kidneys in adult patients with Chronic Kidney Disease (CKD). The main question it aims to answer is:\n\nDo changes in the brain's network connectivity and the retina's blood vessels correlate with cognitive decline and kidney function in CKD patients? Participants with CKD who are already undergoing clinical care will complete cognitive tests and questionnaires, have non-invasive MRI scans of their brain and kidneys, and undergo non-invasive eye imaging (OCT\u002FOCTA) of their retinas.",[50],"Chronic Kidney Diseases",[52,53],"Multimodal magnetic resonance imaging","Montreal Cognitive Assessment","2026-01-25",{"date":56,"type":57},"2026-01-27","ACTUAL",{"date":59,"type":57},"2025-12-01",{"date":61,"type":45},"2031-12-31",{"name":5,"class":6},1]