[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100584765":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":35,"locations":45,"responsibleParty":75,"collaborators":79,"id":85,"slug":86,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":87,"sex":93,"minAge":94,"maxAge":95,"enrollmentInfo":96,"targetDuration":10,"studyType":99,"phases":10,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":47,"whyStopped":10,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Class III Patients treated with bimaxillary surgery",null,"Preoperative and at least 6 months postoperative CBCTs of Patients who suffered from class III facial deformity and had bimaxillary orthognathic surgical correction who undergone maxillary advancement and mandibular setbacks.",[13,17,21,25,28,30,33],{"name":14,"affiliation":15,"role":16},"Ashraf F Ayoub, Professor","Department of Oral and Maxillofacial Surgery, School of Medicine, Dentistry & Nursing, Glasgow Dental Hospital & School, Glasgow, United Kingdom.","STUDY_CHAIR",{"name":18,"affiliation":19,"role":20},"Mohammed Diaa Zain El Abedeen, Professor","Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt","STUDY_DIRECTOR",{"name":22,"affiliation":23,"role":24},"Nehal I Shobair, Lecturer","Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Misr International University, Cairo, Egypt","PRINCIPAL_INVESTIGATOR",{"name":26,"affiliation":27,"role":20},"Xiangyang Ju, Head of Image Processing","Medical Devices Unit, NHS Greater Glasgow and Clyde, Glasgow, United Kingdom",{"name":29,"affiliation":19,"role":20},"Amr A Ghanem, Professor",{"name":31,"affiliation":32,"role":20},"Amr M Ekram, Consultant","Department of Oral and Maxillofacial Surgery, Faculty of Oral and Dental Medicine, Cairo University",{"name":34,"affiliation":32,"role":20},"Ahmed Barakat, Professor",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":10,"email":40},"Nehal I Shobair, PhD","CONTACT","+201063666985","nehal.shobair@miuegypt.edu.eg",{"name":42,"role":38,"phone":43,"phoneExt":10,"email":44},"Yassin S Alian, PhD","+201008161547","Yassinalian@dent.asu.edu.eg",[46,65],{"facility":5,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"RECRUITING","Cairo","Abbassia","11566","Egypt","EG",{"type":54,"coordinates":55},"Point",[56,57],31.24967,30.06263,{"lat":57,"lon":56},[60,62,63],{"name":61,"role":38,"phone":39,"phoneExt":10,"email":40},"Nehal Shobair, Lecturer",{"name":42,"role":38,"phone":43,"phoneExt":10,"email":44},{"name":18,"role":64,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"facility":5,"status":47,"city":49,"state":66,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":10,"geoPoint":10,"contacts":67},"Cairo Governorate",[68,69,73],{"name":22,"role":38,"phone":39,"phoneExt":10,"email":40},{"name":70,"role":38,"phone":71,"phoneExt":10,"email":72},"Mohamed Diaa Zain El Abedeen, Professor","01006030255","diaa67@yahoo.com",{"name":74,"role":64,"phone":10,"phoneExt":10,"email":10},"Amr Ghanem, Professor",{"type":24,"investigatorFullName":76,"investigatorTitle":77,"investigatorAffiliation":78,"oldNameTitle":10,"oldOrganization":10},"Nehal Ibrahim Ahmed Shobair","Lecturer, Department of Oral and Maxillofacial Surgery, Misr International University","Misr International University",[80,81,83],{"name":78,"class":6},{"name":82,"class":6},"University of Glasgow",{"name":84,"class":6},"Cairo University","100584765","facial-conformation-meshes-for-orthognathic-surgery-100584765",false,"NCT06893614","Facial Conformation Meshes for Orthognathic Surgery","Segmented 3D Facial Conformation Meshes and Regional Esthetic Subunits: Advancing Soft Tissue Prediction Planning for Orthognathic Surgery: A Retrospective Study","FEU","Inclusion Criteria:\n\n* Preoperative and at least 6 months postoperative CBCTs of Patients who suffered from class III facial deformity and had bimaxillary orthognathic surgical correction who undergone maxillary advancement and mandibular setbacks.\n\nExclusion Criteria:\n\n* CBCTs of patients with:\n\n  * Craniofacial anomalies including cleft lip\u002Fpalate,\n  * who had had previous maxillofacial operations or facial scars,\n  * Surgical Corrections that required multi-segment Le Fort I osteotomies,\n  * Simultaneous Genioplasty as part of the carried-out corrections.\n  * Significant facial Asymmetry.\n  * Missing Data","ALL","18 Years","50 Years",{"count":97,"type":98},13,"ESTIMATED","OBSERVATIONAL","This study is a retrospective analysis that evaluates the accuracy of 3D soft tissue simulation in bimaxillary orthognathic surgery for Class III dentofacial deformities. The study integrates segmented 3D facial conformation meshes and regional aesthetic subunits to enhance soft tissue prediction accuracy.\n\nKey Aspects of the Study:\n\nStudy Design: Retrospective analysis based on existing CBCT scans of patients who have undergone maxillary advancement and mandibular setback surgery.\n\nObjective: To assess the accuracy of soft tissue predictions using Dolphin software in different facial regions, particularly in midline vs. lateral regions.\n\nMethodology:\n\n.CBCT superimposition using voxel-based registration. .Soft tissue surface analysis via generic mesh conformation and dense correspondence analysis.\n\n.Error assessment in X, Y, Z dimensions rather than Euclidean distance. .Color-coded maps for visualizing prediction accuracy.\n\nClinical Relevance:\n\nThe study aims to refine 3D prediction models for orthognathic surgery planning, making them more precise and reliable.\n\nKey innovation: Modifying the aesthetic unit segmentation approach for a clinically and statistically relevant assessment of soft tissue changes.\n\nFindings will contribute to improving surgical outcome predictability and optimizing treatment planning in maxillofacial surgery.\n\nEthical Considerations:\n\nNo patient recruitment; the study relies solely on existing anonymized CBCT scans.\n\nEthical approval and waiver of informed consent will be sought from the Institutional Review Board (IRB).\n\nThis research aligns with modern advancements in 3D facial prediction technology, aiming to enhance precision and clinical applicability in orthognathic surgery.",[102],"Orthognathic Surgical Procedures",[104,105,106,107,108,109,110],"Orthognathic Surgery","Three-Dimensional Imaging.","Soft Tissue.","Cone-Beam Computed Tomography","Prognathism","Treatment Outcome","Computer Simulation","2025-03-23",{"date":113,"type":114},"2025-03-25","ACTUAL",{"date":116,"type":114},"2025-03-12",{"date":118,"type":98},"2025-05-01",{"name":5,"class":6},2]