[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100619438":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":7,"locations":8,"responsibleParty":27,"collaborators":7,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":35,"acronym":7,"eligibilityCriteria":36,"healthyVolunteers":33,"sex":37,"minAge":38,"maxAge":39,"enrollmentInfo":40,"targetDuration":7,"studyType":43,"phases":7,"briefSummary":44,"conditions":45,"keywords":7,"overallStatus":11,"whyStopped":7,"lastUpdateSubmitDate":47,"lastUpdatePostDateStruct":48,"startDateStruct":51,"completionDateStruct":53,"leadSponsor":55,"locationsCount":56},{"fullName":5,"class":6},"Chinese University of Hong Kong","OTHER",null,[9],{"facility":10,"status":11,"city":12,"state":7,"zip":7,"country":13,"countryCode":14,"cosmosGeoPoint":15,"geoPoint":20,"contacts":21},"The Chinese University of Hong Kong","RECRUITING","Hong Kong","China","CN",{"type":16,"coordinates":17},"Point",[18,19],114.17469,22.27832,{"lat":19,"lon":18},[22],{"name":23,"role":24,"phone":25,"phoneExt":7,"email":26},"Chung PW Jacqueline","CONTACT","35053489","jacquelinechung@cuhk.edu.hk",{"type":28,"investigatorFullName":29,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Chung Pui Wah Jacqueline","Associate Professor","100619438","factors-associated-with-clinical-pregnancy-outcomes-in-intrauterine-insemination-iui-cycles-100619438",false,"NCT07344623","Factors Associated With Clinical Pregnancy Outcomes in Intrauterine Insemination (IUI) Cycles","Inclusion Criteria:\n\n* Couples who underwent at least one IUI-intrauterine insemination cycle.\n\nExclusion Criteria:\n\n* Couples who used donor sperm.\n* Cases with missing core outcome data","FEMALE","18 Years","42 Years",{"count":41,"type":42},3000,"ESTIMATED","OBSERVATIONAL","Hypotheses:\n\nWe hypothesize that variations in hormonal profiles (LH, estradiol, progesterone) during ovarian stimulation, follicular response, endometrial characteristics, and sperm quality parameters are significantly associated with clinical pregnancy outcomes in intrauterine insemination (IUI) cycles.\n\nAims\n\n* To investigate the association between hormonal profiles on the trigger day (LH, estradiol, progesterone), follicular response, endometrial thickness, and sperm parameters with clinical pregnancy outcomes in IUI cycles.\n* To develop and validate a predictive model for clinical pregnancy incorporating key determinants such as female age, hormonal response, endometrial characteristics, and sperm quality.\n* To compare natural and gonadotropin-stimulated IUI cycles in terms of hormonal profiles, pregnancy outcomes, and cost-effectiveness.\n\nPrimary Outcome Clinical pregnancy rate (CPR), defined as the presence of a gestational sac with a fetal heartbeat on ultrasound at approximately 6 weeks of gestation following intrauterine insemination.\n\nSecondary Outcomes\n\n* Biochemical pregnancy rate.\n* Ongoing pregnancy rate\n* Live birth rate",[46],"Reproductive Issues","2026-05-08",{"date":49,"type":50},"2026-05-11","ACTUAL",{"date":52,"type":50},"2026-01-13",{"date":54,"type":42},"2028-01-01",{"name":5,"class":6},1]