[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618220":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":7,"locations":7,"responsibleParty":12,"collaborators":7,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":7,"eligibilityCriteria":22,"healthyVolunteers":18,"sex":23,"minAge":24,"maxAge":25,"enrollmentInfo":26,"targetDuration":7,"studyType":29,"phases":7,"briefSummary":30,"conditions":31,"keywords":33,"overallStatus":37,"whyStopped":7,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":7},{"fullName":5,"class":6},"Pomeranian Medical University Szczecin","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Rehabilitation effective","This study is an observational, non-pharmacological, multi-domain assessment of patients undergoing standard comprehensive cardiac rehabilitation (CR) following CABG surgery. The intervention involves a detailed, longitudinal, three-stage evaluation (Baseline, Post-Rehab, 3-6 Month Follow-up) of the factors influencing CR outcomes.\n\nThe CR itself is a standard hospital-based program, but the research intervention is distinguished by its holistic focus on measuring and correlating:\n\nObjective Functional Data: Exercise capacity (6MWT), muscle strength, diaphragm function (USG), and postural stability.\n\nMultifactorial Co-morbidities: Screening for Obstructive Sleep Apnea (OSA) (NOX-T3), Cognitive Dysfunction (MoCA\u002FMMSE), and the role of oral health in OSA risk.\n\nBiological \\& Hormonal Profile: Measuring Sex Hormones (Testosterone, Estradiol) and Myokines (Irisin, Myostatin) to understand personalized metabolic and adaptive responses to the rehabilitation program.\n\nThe intervention aims to",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Aleksandra Rył","Clinical Professor","100618220","factors-influencing-cardiac-rehabilitation-success-100618220",false,"NCT07328789","Factors Influencing Cardiac Rehabilitation Success","Assessment of the Effectiveness of Comprehensive Cardiac Rehabilitation and Identification of Factors Modulating Its Results","Inclusion Criteria:\n\n* Male patients aged 50-80 years\n* Hospitalization in the Cardiac Rehabilitation Ward\n* Undergone coronary artery bypass graft (CABG) surgery within the last 30 days\n* Written, informed consent to participate in the study\n\nExclusion Criteria:\n\n* Type II diabetes treated with insulin\n* Neuro-surgical operation in the last 6 months\n* Aneurysms of the cerebral arteries and aorta\n* Recurrent ischemic stroke (Cerebral Vascular Accident)\n* Presence of a pacemaker\n* Current treatment with testosterone","ALL","50 Years","80 Years",{"count":27,"type":28},150,"ESTIMATED","OBSERVATIONAL","Cardiovascular diseases, especially after life-saving surgeries, require comprehensive cardiac rehabilitation (CR). We know that the effectiveness of CR varies among patients. The main goal of this study is to understand which factors-psychological, physical, cognitive, biochemical, and hormonal-influence the success and long-term durability of the recovery process. These findings will help us create more effective and personalized treatment programs.\n\nWho is Being Studied and What is Being Assessed? Study Group: 150 patients of both sexes, aged 50-80 years, hospitalized in the cardiac rehabilitation ward, primarily after Coronary Artery Bypass Grafting (CABG).\n\nStudy Period: Patients will be assessed at the start of their hospital stay, at the end of rehabilitation, and again 3-6 months after discharge.\n\nKey Assessment Areas (Modulating Factors)\n\nPhysical Status and Fitness:\n\nExercise tolerance (6-Minute Walk Test).\n\nMuscle strength (handgrip), balance, and gait.\n\nBody composition (analysis of muscle mass and fat tissue).\n\nRespiratory function and diaphragm mobility (ultrasound).\n\nPsychological and Cognitive Factors:\n\nAssessment of anxiety, depression, and general mental well-being.\n\nEvaluation of cognitive functions (memory, concentration) following cardiac surgery.\n\nSleep Problems (OSA):\n\nAssessment of the risk and severity of Obstructive Sleep Apnea (OSA), which is common in cardiac patients.\n\nAnalysis of OSA risk factors related to oral health (dentition, microbiome) and craniofacial structure.\n\nBiological Markers:\n\nHormonal tests (e.g., testosterone, estradiol) and their correlation with psycho-physical condition and the rehabilitation process.\n\nAnalysis of metabolic and muscle-related biomarkers (e.g., myokines: irisin, myostatin).",[32],"Rehabilitation",[34,35,36],"Cardiac Rehabilitation","Sex Hormones","Cognitive Dysfunction","NOT_YET_RECRUITING","2026-01-08",{"date":40,"type":41},"2026-01-09","ACTUAL",{"date":43,"type":28},"2026-01-03",{"date":45,"type":28},"2029-07-01",{"name":5,"class":6}]