[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607038":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":59,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":89,"whyStopped":26,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"The Affiliated Hospital of Qingdao University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group (Standard Care Only)","ACTIVE_COMPARATOR","Participants in this arm will receive standard neoadjuvant chemotherapy followed by radical gastrectomy, along with standard ERAS (Enhanced Recovery After Surgery) perioperative management. No prehabilitation intervention will be provided.",[13],"Other: Standard Care",{"label":15,"type":16,"description":17,"interventionNames":18},"Prehabilitation + Standard Care","EXPERIMENTAL","Participants will receive a family-supervised multimodal prehabilitation program throughout the neoadjuvant chemotherapy period until the day before surgery. The intervention includes personalized nutritional support, home-based exercise training, and psychological counseling, in addition to standard neoadjuvant chemotherapy, surgery, and ERAS management.",[19],"Behavioral: Family-supervised Multimodal Prehabilitation",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Family-supervised Multimodal Prehabilitation","A comprehensive prehabilitation program initiated at the start of neoadjuvant chemotherapy and continued until the day before surgery. The intervention includes:\n\n1. Nutritional support: individualized dietary counseling and supplementation plans supervised by clinical nutritionists;\n2. Exercise training: home-based aerobic and resistance exercises monitored via wearable devices and weekly video\u002Fphone follow-ups;\n3. Psychological support: structured counseling sessions to reduce anxiety, improve treatment adherence, and enhance quality of life.\n\nFamily members are trained to assist with supervision and compliance. The total duration is approximately 10-16 weeks, depending on the chemotherapy schedule.",[15],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard Care","Standard neoadjuvant chemotherapy followed by radical gastrectomy with standard ERAS-based perioperative management, without any additional prehabilitation intervention. Participants receive routine nutritional, nursing and medical care according to hospital guidelines. The aim is to maintain current clinical practice as the control condition for comparison with the experimental prehabilitation program.",[9],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Yanbing Zhou","CONTACT","+86532-82911847","zhouyanbing999@aliyun.com",{"name":38,"role":34,"phone":39,"phoneExt":26,"email":40},"Yuanze Wei","+8619861122261","weiyuanze4385@126.com",[42],{"facility":43,"status":26,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"Qingdao University Affiliated Hospital","Qingdao","Shandong","266003","China","CN",{"type":50,"coordinates":51},"Point",[52,53],120.38042,36.06488,{"lat":53,"lon":52},[56,58],{"name":33,"role":34,"phone":57,"phoneExt":26,"email":36},"+8653282911847",{"name":38,"role":34,"phone":39,"phoneExt":26,"email":40},{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Zhou Yanbing","Chief Physician, Affiliated Hospital of Qingdao University","100607038","family-supervised-prehabilitation-to-reduce-postoperative-complications-after-neoadjuvant-chemotherapy-in-gastric-cancer-100607038",false,"NCT07183358","Family-Supervised Prehabilitation to Reduce Postoperative Complications After Neoadjuvant Chemotherapy in Gastric Cancer","Effect of Family-Supervised Multimodal Prehabilitation Throughout Preoperative Neoadjuvant Chemotherapy on Clinical Outcomes in Gastric Cancer Patients: A Single-Center Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 18-80 years\n* Histologically proven gastric adenocarcinoma by gastroscopy\n* Clinical stage T2-4a, N any, M0 planned for neoadjuvant chemotherapy plus radical gastrectomy\n* ECOG performance status 0-1; ASA class I-III\n* Able to understand the study and provide signed informed consent\n\nExclusion Criteria:\n\n* Previous or concurrent malignancies\n* Emergent conditions (bleeding, perforation, obstruction) requiring immediate surgery\n* Pregnant or lactating women\n* Severe psychiatric disorders\n* Prior major abdominal surgery (except laparoscopic cholecystectomy)\n* Unstable angina, myocardial infarction, or cerebrovascular event within 6 months\n* Continuous use of NSAIDs, corticosteroids, or probiotics within 1 month\n* Simultaneous surgery for other diseases\n* FEV1 \\\u003C 50 % predicted\n* Any condition that, in the investigator's opinion, contraindicates participation","ALL","18 Years","80 Years",{"count":74,"type":75},90,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study evaluates whether a family-supervised exercise-nutrition-psychology program can reduce complications after stomach-cancer surgery. Eligible patients are adults who will receive chemotherapy before surgery. Participants are randomly assigned to either the multimodal prehabilitation program plus usual care or usual care alone. The main outcome is the rate of serious complications within 30 days after surgery. Potential benefits include fewer complications and faster recovery; risks are minimal and mainly related to mild exercise fatigue.",[81,82],"Stomach Neoplasms","Neoadjuvant Therapy",[84,85,86,87,88],"prehabilitation","postoperative complications","multimodal","family-supervised","gastric cancer","NOT_YET_RECRUITING","2025-09-13",{"date":92,"type":93},"2025-09-19","ACTUAL",{"date":95,"type":75},"2025-09-20",{"date":97,"type":75},"2026-06-20",{"name":5,"class":6},1]