[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635940":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":26,"centralContacts":26,"locations":26,"responsibleParty":27,"collaborators":26,"id":31,"slug":32,"hasResults":33,"nctId":34,"briefTitle":35,"officialTitle":36,"acronym":26,"eligibilityCriteria":37,"healthyVolunteers":38,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":26,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":26,"overallStatus":51,"whyStopped":26,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":26},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Flexible and navigable access sheath (FANS)","EXPERIMENTAL","In patients undergoing the FANS procedure , an access sheath with a bendable tip and aspiration feature will be placed into the relevant ureter up to the renal pelvis over the guidewire. The single-use flexible scope will be passed through the access sheath, and the renal collecting system. After this maneuver, the tip of the placed access sheath will be pushed into the renal calyces or pelvis under the guidance of the flexible URS and a holmium fiber will be used to pulverize the stones with a 273-µm fiber. In this group, stones were disintegrated (fragmented) into an adequate size (\\\u003C 3 mm) to allow an efficient extraction with the help of active aspiration, finished by insertion of JJ in all patients.",[13],"Procedure: Flexible ureteroscopy",{"label":15,"type":10,"description":16,"interventionNames":17},"Direct in scope suction (DISS)","In the DISS group, a single-use flexible URS with a direct in-scope suction system will be introduced over the placed guidewire and navigated into the renal pelvis without the use of an access sheath. The suctioning port on the ureteroscope and the laser fiber operates via the same port. In this group, the dusting preset of the same laser device will be used to disintegrate the stones. While continuous irrigation was applied to ensure optimum visualization, finished by insertion of JJ in all patients",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Flexible ureteroscopy","Unlike traditional rigid sheaths, FANS features a deflectable tip that can be guided into specific calyces, allowing for synchronized suction and active fragment evacuation. Conversely, Direct In-Scope Suction (DISS) utilizes a sheathless approach, where suction is integrated directly into the ureteroscope. While DISS avoids potential ureteral trauma associated with access sheaths, FANS is often associated with shorter operative times due to its superior irrigation-aspiration efficiency",[15,9],[25],"FURS",null,{"type":28,"investigatorFullName":29,"investigatorTitle":30,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Armia Ezzat Thabet Azer","resident physician","100635940","fans-vs-diss-in-treatment-of-renal-stone--2cm-100635940",false,"NCT07559214","FANS VS DISS in Treatment of Renal Stone \u003C 2cm","Flexible and Navigable Access Sheath (FANS) VS Direct in Scope Suction (DISS) in Treatment of Renal Stone > 2 cm , Controlled Randomized Trial","Inclusion Criteria:\n\n* All patients \\\u003C 18 years old presented with renal stone \\> 2cm whatever the site of the stone (pelvic or calyceal)\n\nExclusion Criteria:\n\n* Inaccessibility to introduce access sheath or FURS\n* Previous Inserted JJ stent\n* Active UTI\n* Patients refuse to participate in the protocol",true,"ALL","18 Years","60 Years",{"count":43,"type":44},100,"ESTIMATED","INTERVENTIONAL",[47],"NA","To compare between FANS \\& DISS in :\n\n* Operative time\n* Stone free rate\n* Complications\n* Amount of fluid irrigation",[50],"Renal Calculi","NOT_YET_RECRUITING","2026-04-23",{"date":54,"type":55},"2026-04-30","ACTUAL",{"date":57,"type":44},"2026-06",{"date":59,"type":44},"2027-09",{"name":5,"class":6}]