[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100564753":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":25,"responsibleParty":42,"collaborators":44,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":10,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":28,"whyStopped":10,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},{"fullName":5,"class":6},"University of Bonn","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Nanopore sequencing",null,"All adult patients at with suspected diagnosis of breast cancer undergoing biopsy or surgical resection will be offered to participate in the study. After informed written consent excess tissue is preserved for DNA extraction using commercial spin column kits and will be further analyzed.",[13],{"name":14,"affiliation":15,"role":16},"Oliver Henke, MD","Section Global Health, University Hospital Bonn","PRINCIPAL_INVESTIGATOR",[18,22],{"name":14,"role":19,"phone":20,"phoneExt":10,"email":21},"CONTACT","+49 (0) 228 287 51521","Oliver.Henke@ukbonn.de",{"name":23,"role":19,"phone":20,"phoneExt":10,"email":24},"Maximilian Rost, MD","maximilian.rost@ukbonn.de",[26],{"facility":27,"status":28,"city":29,"state":10,"zip":30,"country":31,"countryCode":10,"cosmosGeoPoint":32,"geoPoint":37,"contacts":38},"Kilimanjaro Christian Medical Centre","RECRUITING","Moshi","P.O. Box 3010","Tanzania",{"type":33,"coordinates":34},"Point",[35,36],37.33333,-3.35,{"lat":36,"lon":35},[39],{"name":40,"role":19,"phone":41,"phoneExt":10,"email":21},"Oliver Henke","+255 (0) 76 1511227",{"type":16,"investigatorFullName":40,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Head of Working Group Global Oncology, Section Global Health, University Hospital Bonn",[45,47],{"name":46,"class":6},"German Cancer Research Center",{"name":48,"class":49},"Kilimanjaro Christian Medical Centre,Moshi,Tanzania","UNKNOWN","100564753","fast-and-accurate-breast-cancer-diagnosis-using-nanopore-sequencing-in-tanzania-fast-abcd-sequencing-100564753",false,"NCT06633276","Fast and Accurate Breast Cancer Diagnosis Using Nanopore Sequencing in Tanzania (Fast-ABCD Sequencing)","Nanopore Sequencing for Accelerating Breast Cancer Diagnosis in Tanzania: A Prospective Observational Study","Inclusion Criteria:\n\n* Patient with suspected diagnosis of breast cancer undergoing biopsy or surgical resection after specialist consultation as per institutional guidelines\n* Excess fresh tumor sample\n* Written informed consent\n\nExclusion Criteria:\n\n* Unable to provide informed consent\n* Patients who have already commenced therapy for BC (except for treatment other than biomedicine, e.g. herbal medicines)","ALL","18 Years",{"count":60,"type":61},100,"ESTIMATED","OBSERVATIONAL","This pilot study will test the feasibility of using nanopore sequencing for breast cancer diagnosis in Tanzania. It aims to show that nanopore sequencing is non-inferior to the current standard of care, with the potential for faster and more cost-efficient results. By enhancing the speed and accuracy of diagnosis, this approach could improve treatment planning and outcomes for patients in resource-limited settings.",[65],"Breast Cancer Invasive",[9,67],"breast cancer","2025-05-08",{"date":70,"type":71},"2025-05-14","ACTUAL",{"date":73,"type":61},"2025-05",{"date":75,"type":61},"2026-05",{"name":5,"class":6},1]