[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100562556":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":20,"responsibleParty":28,"collaborators":20,"id":32,"slug":33,"hasResults":34,"nctId":35,"briefTitle":36,"officialTitle":37,"acronym":20,"eligibilityCriteria":38,"healthyVolunteers":34,"sex":39,"minAge":40,"maxAge":41,"enrollmentInfo":42,"targetDuration":20,"studyType":45,"phases":46,"briefSummary":48,"conditions":49,"keywords":53,"overallStatus":59,"whyStopped":20,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":20},{"fullName":5,"class":6},"Cairo University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Fat Injection for Rectocele","EXPERIMENTAL","Participants in this arm will undergo autologous fat injection as a novel treatment for rectocele. Fat grafts will be harvested from the patient's abdomen, processed to purify the fat, and injected into the submucosal layer of the rectocele through the posterior vaginal wall. This procedure aims to reduce the size of the rectocele, alleviate symptoms like vaginal bulge and obstructive defecation, and prevent recurrence.",[13],"Procedure: Autologous Fat Injection for Rectocele",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"PROCEDURE","Autologous Fat Injection for Rectocele","In this procedure, autologous fat is harvested from the patient\\'s lower abdomen using a multiport cannula. The fat is then processed via centrifugation to separate the viable fat cells, which are emulsified into nanofat. This nanofat is injected into the submucosal layer of the rectocele through the posterior vaginal wall, using an anoscope for guidance. The procedure is intended to reinforce the rectovaginal fascia, alleviate rectocele symptoms such as obstructive defecation and vaginal bulge, and reduce prolapse recurrence.",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":26,"email":27},"Eslam Mohamed Hagagy Mohamed, MSc","CONTACT","01020487095","+2","Eslam22hego@gmail.com",{"type":29,"investigatorFullName":30,"investigatorTitle":31,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Eslam Mohamed Hagagy Mohamed","Resident of the General Surgery, Cairo University","100562556","fat-injection-for-rectocele-treatment-a-novel-approach-100562556",false,"NCT06604702","Fat Injection for Rectocele Treatment: A Novel Approach","Fat Injection for Treatment of Rectocele a Novel Technique for Treatment of Tectocele","Inclusion Criteria:\n\n* Female patients aged between 18 and 60 years.\n* Diagnosis of rectocele confirmed by defecography, with a rectocele size of 2 cm (mild) to 4 cm (moderate).\n* Presenting with symptoms of obstructive defecation syndrome, including constipation, incomplete defecation, and\u002For vaginal bulge.\n* Able to provide written informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Patients who have previously undergone surgical repair of rectocele.\n* Presence of thrombosed hemorrhoids.\n* History of sclerotherapy injection for rectocele.\n* Diagnosis of anal stenosis.\n* History of coagulopathy or current use of anticoagulant or antiplatelet medications.\n* Refusal or inability to provide informed consent.","FEMALE","18 Years","60 Years",{"count":43,"type":44},25,"ESTIMATED","INTERVENTIONAL",[47],"NA","This clinical trial aims to evaluate the effectiveness of autologous fat grafting as a novel treatment for rectocele, a condition characterized by the herniation of rectal tissue into the posterior vaginal wall. Women aged 18 to 60 years with mild to moderate rectocele, presenting with symptoms such as obstructive defecation or vaginal bulge, will undergo submucosal fat injections. The study will assess the procedure\\'s ability to alleviate symptoms and reduce prolapse recurrence. This prospective, single-arm trial will be conducted at Cairo University Hospitals.",[50,51,52],"Rectocele","Pelvic Organ Prolapse","Obstructive Defecation Syndrome",[50,54,55,56,57,51,58],"Pelvic Floor Dysfunction","Fat Grafting","Autologous Fat Injection","Obstructive Defecation","Vaginal Bulge","NOT_YET_RECRUITING","2024-09-17",{"date":62,"type":63},"2024-09-19","ACTUAL",{"date":65,"type":44},"2024-10-20",{"date":67,"type":44},"2025-10-20",{"name":5,"class":6}]