[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100564749":3},{"organization":4,"armGroups":7,"interventions":16,"overallOfficials":36,"centralContacts":40,"locations":46,"responsibleParty":69,"collaborators":71,"id":75,"slug":76,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":10,"eligibilityCriteria":81,"healthyVolunteers":77,"sex":82,"minAge":83,"maxAge":10,"enrollmentInfo":84,"targetDuration":10,"studyType":87,"phases":10,"briefSummary":88,"conditions":89,"keywords":95,"overallStatus":48,"whyStopped":10,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cancer Patients",null,"Participants will have blood and stool samples collected within 5 days of any pre or post treatment timepoint prior to, during, at completion of therapy and up to 34 weeks following non-investigational, standard of care, CCRT. Participants will also be given quality of life questionnaires to complete throughout the course of the study.",[13,14,15],"Procedure: Blood Specimen Collection","Other: Stool Specimen Collection","Other: Quality of Life (QOL) Questionnaires",[17,24,30],{"type":18,"name":19,"description":20,"armGroupLabels":21,"otherNames":22},"PROCEDURE","Blood Specimen Collection","Blood samples will be obtained throughout the course of the study",[9],[23],"Blood Specimen",{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":28},"Stool Specimen Collection","Stool samples will be obtained throughout the course of the study",[9],[29],"Stool Specimen",{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Quality of Life (QOL) Questionnaires","Surveys will be given throughout the course of the study.",[9],[35],"Quality of Life Surveys",[37],{"name":38,"affiliation":5,"role":39},"Sue Yom, MD","PRINCIPAL_INVESTIGATOR",[41],{"name":42,"role":43,"phone":44,"phoneExt":10,"email":45},"Jamese Johnson","CONTACT","(415) 530-9805","Jamese.Johnson@ucsf.edu",[47],{"facility":5,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"RECRUITING","San Francisco","California","94143","United States","US",{"type":55,"coordinates":56},"Point",[57,58],-122.41942,37.77493,{"lat":58,"lon":57},[61,63,66,67],{"name":42,"role":43,"phone":62,"phoneExt":10,"email":45},"415-530-9805",{"name":10,"role":43,"phone":64,"phoneExt":10,"email":65},"877-827-3222","cancertrials@ucsf.edu",{"name":38,"role":39,"phone":10,"phoneExt":10,"email":10},{"name":68,"role":39,"phone":10,"phoneExt":10,"email":10},"Kord M Kober, PhD",{"type":70,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[72],{"name":73,"class":74},"National Cancer Institute (NCI)","NIH","100564749","fatigue-and-molecular-mechanisms-in-cancer-patients-receiving-ccrt-100564749",false,"NCT06633224","Fatigue and Molecular Mechanisms in Cancer Patients Receiving CCRT","An Evaluation of Changes in the Relationships Between Fatigue and Molecular Mechanisms in Cancer Patients Receiving Curative-Intent Combined Chemotherapy and Radiation Therapy (CCRT)","Inclusion Criteria:\n\n* Participants have not received any prior treatment (i.e., cancer systemic therapies or radiation therapy) in the month except surgery or inductive Chemotherapy (CTX).\n* Participants receiving \\>= 15 fractions.\n* Participants is male or female and is \\>18 years of age on the day of signing the informed consent.\n* Ability to understand a written informed consent document.\n* Able and willing to complete all of the study questionnaires and provide blood and stool samples prior to, midway, and following the completion of treatment.\n* Willing to have medical records reviewed for clinical information.\n* Able to read, write and understand English or Spanish.\n\nExclusion Criteria:\n\n* Contraindication to phlebotomy for removal of approximately 50 mL of peripheral blood within 6 week period (Institutional Review Board (IRB) limit).","ALL","18 Years",{"count":85,"type":86},125,"ESTIMATED","OBSERVATIONAL","Cancer-related fatigue (CRF) is a significant problem for cancer patients. This prospective, basic science, observational study will evaluate for changes in CRF associated with molecular characteristics prior to, during, and at the completion of non-investigational, standard-of-care, combined chemotherapy and radiation therapy (CCRT) and to develop and assess predictive models for CRF severity.",[90,91,92,93,94],"Cancer","Thoracic Cancer","Gynecologic Cancer","Head and Neck Cancer","Gastrointestinal Cancer",[96],"Basic Science Research","2025-09-09",{"date":99,"type":100},"2025-09-16","ACTUAL",{"date":102,"type":100},"2024-12-27",{"date":104,"type":86},"2027-09-01",{"name":5,"class":6},1]