[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611347":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":23,"centralContacts":18,"locations":18,"responsibleParty":27,"collaborators":18,"id":29,"slug":30,"hasResults":31,"nctId":32,"briefTitle":33,"officialTitle":34,"acronym":18,"eligibilityCriteria":35,"healthyVolunteers":31,"sex":36,"minAge":37,"maxAge":18,"enrollmentInfo":38,"targetDuration":18,"studyType":41,"phases":42,"briefSummary":44,"conditions":45,"keywords":47,"overallStatus":52,"whyStopped":18,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":18},{"fullName":5,"class":6},"Pakistan Association of Cognitive Therapists","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Culturally adapted guided self-help OCD","EXPERIMENTAL","Participants will receive a culturally adapted guided self-help OCD manual based on culturally adapted CBT principles, designed to be used over ten weeks. The manual includes: Psychoeducation, Exposure and Response Prevention (ERP), Thought distraction techniques, Mood tracking and thought diaries, Identifying and modifying cognitive distortions, Problem-solving and communication strategies, and Relaxation and well-being exercises. Participants will receive the self-help manual at the time of initial assessment and intake, and then will be provided with telephone support. Psychology graduates working as guides will provide weekly telephone support. Intervention will be provided flexibly over 12 weeks. The second contact will be made at the time of final assessment on the 12th week.",[13],"Other: Culturally adapted Guided Self-Help OCD Manual",{"label":15,"type":16,"description":17,"interventionNames":18},"Treatment as Usual (TAU)","NO_INTERVENTION","Participants in the control group will receive standard outpatient care, which typically includes medication and brief consultation with psychiatrists or general practitioners. No formal psychological intervention will be offered during the study period. Pre-post assessment will be conducted over a 12-week span.",null,[20],{"type":6,"name":21,"description":11,"armGroupLabels":22,"otherNames":18},"Culturally adapted Guided Self-Help OCD Manual",[9],[24],{"name":25,"affiliation":5,"role":26},"Mirrat Gul Butt, PhD","PRINCIPAL_INVESTIGATOR",{"type":28,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100611347","feasibility-and-efficacy-trial-of-a-culturally-adapted-guided-self-help-cbt-manual-for-ocd-100611347",false,"NCT07239401","Feasibility and Efficacy Trial of a Culturally Adapted Guided Self-Help CBT Manual for OCD","Feasibility and Efficacy Trial of a Culturally Adapted Guided Self-Help CBT Manual for Obsessive-Compulsive Disorder: A Randomised Controlled Study From Pakistan","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Clinical diagnosis of OCD (with or without comorbid depression)\n* Minimum 5 years of formal education\n* Residing within commuting distance of the participating sites\n* Ability to read and write Urdu\n* Provision of informed written consent\n\nExclusion Criteria:\n\n* Current substance use or dependence (diagnosed)\n* Significant cognitive impairment (e.g., dementia or intellectual disability)\n* OCD with active psychosis","ALL","18 Years",{"count":39,"type":40},108,"ESTIMATED","INTERVENTIONAL",[43],"NA","This randomised controlled trial (RCT) aims to assess the feasibility, acceptability, and preliminary efficacy of a culturally adapted, guided self-help cognitive behaviour therapy (CBT) manual specifically designed for individuals with OCD in Pakistan.",[46],"Obsessive - Compulsive Disorder",[48,49,50,51],"OCD","Obsessive compulsive disorder","Guided self-help","CBT","NOT_YET_RECRUITING","2025-11-15",{"date":55,"type":56},"2025-11-20","ACTUAL",{"date":58,"type":40},"2025-11",{"date":60,"type":40},"2026-02",{"name":5,"class":6}]