[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621148":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":30,"locations":40,"responsibleParty":55,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":65,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":26,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":88,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"General Hospital of Ningxia Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Lateral Mid-femoral Approach Sciatic Nerve Block","EXPERIMENTAL","Ultrasound-guided sciatic nerve subparaneural sheath block via the lateral mid-femoral approach. Under combined ultrasound and nerve stimulator guidance, a single injection of 20 mL of 0.5% ropivacaine hydrochloride will be administered into the paraneural sheath at the mid-femoral level.",[13],"Procedure: Ultrasound-guided lateral mid-femoral sciatic nerve block",{"label":15,"type":16,"description":17,"interventionNames":18},"Popliteal Approach Sciatic Nerve Block","ACTIVE_COMPARATOR","Ultrasound-guided sciatic nerve subparaneural sheath block via the conventional popliteal approach. Under combined ultrasound and nerve stimulator guidance, a single injection of 20 mL of 0.5% ropivacaine hydrochloride will be administered into the paraneural sheath at the popliteal fossa (prior to nerve bifurcation).",[19],"Procedure: Ultrasound-guided popliteal sciatic nerve block",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Ultrasound-guided lateral mid-femoral sciatic nerve block","Ultrasound-guided sciatic nerve subparaneural sheath block via the lateral mid-femoral approach. Under combined ultrasound and nerve stimulator guidance, a single injection of 20 mL of 0.5% ropivacaine hydrochloride will be administered into the paraneural sheath at the mid-femoral level",[9],null,{"type":22,"name":28,"description":17,"armGroupLabels":29,"otherNames":26},"Ultrasound-guided popliteal sciatic nerve block",[15],[31,36],{"name":32,"role":33,"phone":34,"phoneExt":26,"email":35},"Gang Ma, MD，PhD","CONTACT","13709519220","magang2671@173.com",{"name":37,"role":33,"phone":38,"phoneExt":26,"email":39},"Yan Ren, MD","18152372612","3467592762@qq.com",[41],{"facility":5,"status":26,"city":42,"state":43,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Yinchuan","Ningxia","750004","China","CN",{"type":48,"coordinates":49},"Point",[50,51],106.27306,38.46806,{"lat":51,"lon":50},[54],{"name":37,"role":33,"phone":38,"phoneExt":26,"email":39},{"type":56,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100621148","feasibility-and-safety-of-sciatic-nerve-paraneural-sheath-block-using-a-mid-femoral-lateral-approach-100621148",false,"NCT07366853","Feasibility and Safety of Sciatic Nerve Paraneural Sheath Block Using a Mid-Femoral Lateral Approach","Feasibility and Safety of Intraneural Sciatic Nerve Block Via Lateral Mid-femoral Approach: A Clinical Study","iSNB-LF","Inclusion Criteria:\n\n1. Patients scheduled for elective unilateral surgery below the knee (e.g., internal fixation for ankle, metatarsal, or calcaneal fractures; hallux valgus correction; flatfoot reconstruction).\n2. American Society of Anesthesiologists (ASA) physical status class I or II.\n3. Aged 18 to 65 years.\n4. Ability to understand the study procedure and provide written informed consent.\n\nExclusion Criteria:\n\n1. Contraindications to peripheral nerve block:\n\n   * Known allergy or history of toxicity to local anesthetics.\n   * Pre-existing neuropathy in the operative limb.\n   * Severe coagulopathy.\n   * Infection at the intended needle puncture site.\n   * Systemic infection.\n2. Requirement for simultaneous surgery at a site other than the unilateral lower limb below the knee.\n3. Previous surgery or significant scarring in the area of the planned needle insertion for the sciatic nerve block.\n4. Body mass index (BMI) \\> 35 kg\u002Fm².\n5. Patients receiving chronic pain therapy or with a history of opioid abuse.\n6. Inability to communicate or cooperate with the study assessments (e.g., due to cognitive impairment, language barrier, or psychiatric disorder).\n7. Pregnancy or lactation.",true,"ALL","18 Years","65 Years",{"count":70,"type":71},200,"ESTIMATED","INTERVENTIONAL",[74],"NA","This study is designed as a randomized controlled trial aiming to evaluate the feasibility and safety of ultrasound-guided mid-femoral lateral approach sciatic nerve paraneural sheath block, in order to provide a new sciatic nerve block approach for clinical practice that offers greater patient comfort and higher precision, thereby facilitating its use for specific patient populations and less experienced operators.",[77,78,79],"Adverse Effect","Feasibility Study","Safety and Effectiveness",[81,82,83,84,85,86,87],"Sciatic Nerve Block","Subparaneural Block","Lateral Mid-femoral Approach","Popliteal Approach","Ultrasound-guided","Feasibility","Safety","NOT_YET_RECRUITING","2026-01-16",{"date":91,"type":92},"2026-01-26","ACTUAL",{"date":94,"type":71},"2026-01-01",{"date":96,"type":71},"2026-10-01",{"name":5,"class":6},1]