[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625708":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":53,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":62,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":60,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":70,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":10,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Shanghai First Maternity and Infant Hospital","OTHER",[8,13],{"label":9,"type":10,"description":10,"interventionNames":11},"Dietary regulation group",null,[12],"Other: low glycemic index-high fiber",{"label":14,"type":10,"description":10,"interventionNames":10},"control",[16],{"type":6,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"low glycemic index-high fiber","This was a prospective, single-center intervention study designed to evaluate the feasibility and metabolic\u002Freproductive effects of an adaptive low glycemic index, high-fiber diet (LGI-HF) on women with polycystic ovary syndrome (PCOS) residing in remote mountainous areas of Yunnan, China. The intervention lasted 24 weeks, with assessments at baseline (week 0), mid-intervention (week 12), and end of intervention (week 24)",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Zhiqin Chen, Doctor","CONTACT","86+13671686734","ptchen1@hotmail.com",[27,40],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":10,"geoPoint":10,"contacts":35},"Department of Gynaecology, Gengma People's Hospital","RECRUITING","Gengma County","Yunnan","677500","China","CN",[36],{"name":37,"role":23,"phone":38,"phoneExt":10,"email":39},"Xueyan Wu Doctor","86+18806973797","18806973797@163.com",{"facility":41,"status":29,"city":42,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Gengma People's Hospital","Lincang",{"type":44,"coordinates":45},"Point",[46,47],100.09455,23.87972,{"lat":47,"lon":46},[50],{"name":51,"role":23,"phone":24,"phoneExt":10,"email":52},"fan hao Doctor","syhfg512006@163.com",{"type":54,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[56],{"name":41,"class":57},"UNKNOWN","100625708","feasibility-effects-of-a-low-gi-high-fibre-diet-in-pcos-a-prospective-cohort-study-in-remote-yunnan-100625708",false,"NCT07426146","Feasibility Effects of a Low-GI, High-fibre Diet in PCOS: a Prospective Cohort Study in Remote Yunnan","Inclusion Criteria:\n\n* PCOS diagnosis will follow the Rotterdam criteria (presence of two of the following three features: oligo-\u002Fanovulation, clinical\u002Fbiochemical hyperandrogenism, and polycystic ovarian morphology, with exclusion of related disorders). Additional inclusion criteria comprise: body mass index (BMI) ≥24 kg\u002Fm² (Chinese obesity threshold), stable weight for at least 3 months prior to enrollment (±2 kg), willingness to maintain current physical activity levels throughout the study period, and residence within the designated study area for a minimum of 6 months.\n\nExclusion Criteria:\n\n* pregnancy or lactation; type 1 diabetes or type 2 diabetes; thyroid dysfunction, hyperprolactinemia, congenital adrenal hyperplasia, Cushing's syndrome, androgen-secreting tumors, or other endocrine disorders affecting metabolism; use of hormonal contraceptives, insulin sensitizers, or anti-obesity medications within the past 3 months (e.g., metformin, GLP-1 receptor agonists, systemic corticosteroids, hormonal contraceptives, anti-androgens). Severe hepatic\u002Frenal\u002Fcardiovascular disease; gastrointestinal disorders incompatible with high-fiber diets; history of bariatric surgery; current participation in other dietary intervention programs; and individuals with cognitive impairment or language communication barriers who cannot comprehend the study procedures or provide informed consent. Participants will be required to maintain their habitual physical activity levels during the intervention period and must not initiate new weight-loss medications\u002Fsupplements; any deviations will be documented as protocol violations","FEMALE","19 Years","40 Years",{"count":68,"type":69},56,"ESTIMATED","6 Months","OBSERVATIONAL","This study aims to observe the effects of a 6-month, culturally-adapted low glycemic index-high fiber (LGI-HF) dietary on IR, androgen levels, and menstrual regularity among women with PCOS in remote areas of Yunnan Province. We hypothesize that a nutritional strategy designed for high-carbohydrate dietary habits while balancing feasibility and adherence can significantly improve patients' metabolic and reproductive parameters, thereby providing practical evidence-based guidance for long-term PCOS management in resource-limited settings",[74],"PCOS (Polycystic Ovary Syndrome)","2026-02-15",{"date":77,"type":78},"2026-02-23","ACTUAL",{"date":80,"type":78},"2025-08-10",{"date":82,"type":69},"2026-04-10",{"name":5,"class":6},2]