[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100563018":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":34,"responsibleParty":48,"collaborators":52,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":19,"enrollmentInfo":67,"targetDuration":19,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":82,"whyStopped":19,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"London Health Sciences Centre","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Cardiac Prehabilitation for CTO Patients","EXPERIMENTAL","This single arm involves a 6-month cardiac pre-habilitation program designed for patients with chronic total occlusions (CTO) who are referred for percutaneous coronary intervention (PCI). Participants receive personalized cardiac rehabilitation, which includes physical exercise, medical optimization, and lifestyle modifications. The program aims to improve functional capacity and overall health before PCI. Assessments will be conducted at the start, after 6 months, and one month post-PCI if performed, with ongoing virtual follow-up for 5 months if PCI is not needed.",[13],"Other: Cardiac Prehabilitation Program",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Cardiac Prehabilitation Program","Patients begin with a one-on-one assessment by a program cardiologist and a CR nurse, followed by a symptom-limited cardiopulmonary exercise test (CPET) to tailor their exercise regimen. The exercise program, based on the FITT (frequency, intensity, time, and type) principle, includes biweekly sessions either at home or at a commercial gym, with ongoing oversight by SJHC CRSP rehabilitation trainers. Additionally, participants have access to dietary counseling to optimize heart-healthy nutrition.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Luiz F Ybarra, MD PhD MBA FRCPC","PRINCIPAL_INVESTIGATOR",[25,30],{"name":22,"role":26,"phone":27,"phoneExt":28,"email":29},"CONTACT","519-685-8500","33036","Luiz.Ybarra@lhsc.on.ca",{"name":31,"role":26,"phone":27,"phoneExt":32,"email":33},"Shirin Shadpour","35625","shirin.shadpour@lhsc.on.ca",[35],{"facility":36,"status":19,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":19},"University Hospital","London","Ontario","N6A 5A5","Canada","CA",{"type":43,"coordinates":44},"Point",[45,46],-81.23304,42.98339,{"lat":46,"lon":45},{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"SPONSOR_INVESTIGATOR","Luiz Ybarra","Interventional Cardiologist, Principal Investigator",[53,55],{"name":54,"class":6},"Academic Medical Organization of Southwestern Ontario",{"name":56,"class":6},"University of Western Ontario, Canada","100563018","feasibility-of-a-cardiac-rehabilitation-program-for-cto-patients-before-pci-treatment-100563018",false,"NCT06610708","Feasibility of a Cardiac Rehabilitation Program for CTO Patients Before PCI Treatment","Pre-Intervention Rehabilitation to Optimize Patient Selection for Chronic Total Occlusion Percutaneous Coronary Interventions (PREHAB-CTO Study)","PREHAB-CTO","Inclusion Criteria:\n\n1. The presence of a chronic total occlusion in at least one major coronary artery (diameter ≥ 2.5mm).\n2. Patients who have an indication for percutaneous coronary intervention of a CTO, which includes the presence of:\n\n   1. Angina or anginal-equivalent symptoms and\n   2. Ischemia or viability in the CTO territory\n3. Patient aged ≥18 years of age.\n\nExclusion Criteria:\n\n1. Inability or refusal to participate in the study's cardiac rehabilitation program.\n2. Participation in CR program in the last 1 year.\n3. Life expectancy of \\< 12 months due to non-cardiovascular comorbidities.\n4. Anatomy deemed unsuitable for CTO PCI.\n5. Severe left main disease (angiographic stenosis ≥50%; fractional flow reserve ≤0.80; minimal lumen area \\<6mm2).\n6. Severe valvular disease or valvular disease likely to require surgery or percutaneous valve replacement during the study period.\n7. Pregnancy.\n8. Acute coronary syndrome within two months.\n9. Canadian Cardiovascular Society Class ≥III angina of recent onset.\n10. Angina of any class with a rapidly accelerating pattern.\n11. Cardiac transplant recipient.\n12. Inability to understand the questionnaires used in the study.\n13. Patients unable to provide consent for the study.","ALL","18 Years",{"count":68,"type":69},70,"ESTIMATED","INTERVENTIONAL",[72],"NA","The goal of this clinical trial is to evaluate the feasibility of a cardiac pre-hab program for patients with blocked arteries (CTO) who are referred for PCI treatment. The main questions it aims to answer are:\n\nCan the pre-hab program improve patients\\' functional capacity before PCI? Does the pre-hab program impact the need for PCI based on improvements in patients\\' health?\n\nParticipants will:\n\nUndergo an initial assessment including a physical exam, medication history, quality of life questionnaires, and blood work.\n\nComplete a 6-month cardiac rehabilitation program. Have repeat assessments to evaluate improvements and determine if PCI is still needed.\n\nIf PCI is performed, be assessed again one month later for functional capacity improvements.\n\nIf PCI is not needed after 6 months, participants will be followed virtually for an additional 5 months.",[75],"Chronic Total Occlusion (CTO)",[77,78,79,80,81],"CTO","Chronic Total Occlusion","Prehabilitation","Prehab","PCI","NOT_YET_RECRUITING","2024-09-23",{"date":85,"type":86},"2024-09-24","ACTUAL",{"date":88,"type":69},"2024-10",{"date":90,"type":69},"2026-10",{"name":50,"class":6},1]