[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579723":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":18,"locations":23,"responsibleParty":49,"collaborators":18,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":18,"eligibilityCriteria":58,"healthyVolunteers":54,"sex":59,"minAge":60,"maxAge":18,"enrollmentInfo":61,"targetDuration":18,"studyType":64,"phases":65,"briefSummary":67,"conditions":68,"keywords":70,"overallStatus":77,"whyStopped":18,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University of Toronto","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Resistance Training","EXPERIMENTAL","The resistance training intervention will consist of two remotely-delivered exercise sessions per week for eight weeks (16 sessions total). One session will be a live, remotely delivered 1:1 class led by a qualified exercise professional (\\~one hour). The second session will be unsupervised, completed by watching a pre-recorded workout video that will vary bi-weekly to elicit progressive overload. Pre-recorded workout videos will be emailed and feature the qualified exercise professional who will provide instruction to mimic live sessions. Both sessions will involve a dynamic warm-up (\\~10 minutes), 8 resistance-band exercises (\\~30-45 minutes), followed by a cool-down (\\~10 minutes).",[13],"Behavioral: Resistance Training",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care","NO_INTERVENTION","The usual care group will receive exercise guidelines for cancer survivors (i.e., educational material) from the American College of Sport Medicine. Exercise guidelines materials will be provided through email.",null,[20],{"type":21,"name":9,"description":11,"armGroupLabels":22,"otherNames":18},"BEHAVIORAL",[9],[24],{"facility":5,"status":18,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Toronto","Ontario","M5S2W6","Canada","CA",{"type":31,"coordinates":32},"Point",[33,34],-79.39864,43.70643,{"lat":34,"lon":33},[37,42,45,47],{"name":38,"role":39,"phone":40,"phoneExt":18,"email":41},"Sarah O'Rourke, BA","CONTACT","4169463624","s.orourke@mail.utoronto.ca",{"name":43,"role":39,"phone":40,"phoneExt":18,"email":44},"Linda Trinh, PhD","linda.trinh@utoronto.ca",{"name":38,"role":46,"phone":18,"phoneExt":18,"email":18},"PRINCIPAL_INVESTIGATOR",{"name":43,"role":48,"phone":18,"phoneExt":18,"email":18},"SUB_INVESTIGATOR",{"type":46,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Linda Trinh","Associate Professor","100579723","feasibility-of-a-remotely-delivered-resistance-training-program-for-cognitive-function-in-men-living-with-and-beyond-prostate-cancer-100579723",false,"NCT06828003","Feasibility of a Remotely-Delivered Resistance Training Program for Cognitive Function in Men Living With and Beyond Prostate Cancer","A Remotely-Delivered Resistance Training Program for Cognitive Function in Men Living With and Beyond Prostate Cancer: A Feasibility Study","Inclusion Criteria:\n\n* ≥18 years of age\n* localized or asymptomatic metastatic primary prostate cancer (i.e., androgen receptor axis agents \\[ARATs\\] including conventional ADT, abiraterone, enzalutamide)\n* a history of ADT treatment\n* not currently undergoing radiation\n* no neurological or musculoskeletal co-morbidity inhibiting exercise\n* mild cognitive impairment as determined by the TICS-M \\[scores between 21-24 to separate individuals with mild cognitive impairment and normal cognition (\\>24)\\]\n* not physically active (self-report \\\u003C90 minutes of MVPA\u002Fweek and \\\u003C2 days of RT\u002Fweek)\n* physician clearance to participate\n* access to a webcam and internet\n* able to complete the study in English.\n\nExclusion Criteria:\n\n* a medical condition that prevents unsupervised exercise\n* presence of other primary or recurrent invasive cancer\n* have experienced a fall in the last 12 months\n* use a gait aid device\n* current participation in other exercise programs\u002Ftrials\n* colour-blind since the objective cognitive tests require participants to distinguish between colours.","MALE","18 Years",{"count":62,"type":63},30,"ESTIMATED","INTERVENTIONAL",[66],"NA","Prostate cancer and its treatment are associated with many long-term adverse effects including cancer-related cognitive impairment. Specifically, androgen deprivation therapy has been shown to negatively impact cognitive function. Combined aerobic and resistance training has been shown to improve cognitive function in men treated with androgen deprivation therapy, but limited research has observed its impact into survivorship. Additionally, existing study designs are limited to supervised, combined aerobic and resistance training interventions. Remotely-delivered resistance training programs could enhance exercise participation by overcoming commonly reported barriers in men living with and beyond prostate cancer such as transportation, distance to facility, and timing of programs. Alongside the needs to address cancer-related cognitive impairments due to androgen deprivation therapy, resistance training may serve to manage functional deficits, losses in bone mineral density and muscle mass and increases in cardiometabolic risk factors. This study will assess the feasibility of an 8-week remotely-delivered resistance training program to improve cognitive function in men living with and beyond prostate cancer who have a history of androgen deprivation therapy treatment.",[69,9],"Prostate Cancer",[71,72,73,74,75,76],"cancer survivorship","cognitive function","prostate cancer","remote delivery","feasibility","resistance training","NOT_YET_RECRUITING","2025-02-10",{"date":80,"type":81},"2025-02-14","ACTUAL",{"date":83,"type":63},"2025-03-01",{"date":85,"type":63},"2026-01",{"name":5,"class":6},1]