[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608039":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":44,"responsibleParty":86,"collaborators":89,"id":96,"slug":97,"hasResults":98,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":102,"eligibilityCriteria":103,"healthyVolunteers":98,"sex":104,"minAge":105,"maxAge":106,"enrollmentInfo":107,"targetDuration":25,"studyType":110,"phases":111,"briefSummary":113,"conditions":114,"keywords":116,"overallStatus":60,"whyStopped":25,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":134},{"fullName":5,"class":6},"University of New Brunswick","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Aerobic Training with Blood Flow Restriction","EXPERIMENTAL","Participants will perform aerobic training with blood flow restriction.",[13],"Behavioral: Aerobic Training with Blood Flow Restriction",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Aerobic Training","ACTIVE_COMPARATOR","Participants will perform aerobic training.",[19],"Behavioral: Standard Aerobic Training",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Participants will undergo a 6-week aerobic training intervention with blood flow restriction applied to the lower limbs.\n\nBlood flow restriction will be applied using a blood pressure cuff set between 60-80% of limb arterial occlusion pressure.\n\nTraining will consist of treadmill walking at 40-50% of heart rate reserve (HRR) for 32 minutes per session, 3 times per week for a total of 96 minutes per week.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Participants will follow the same aerobic training protocol as the AT+BFR group but without blood flow restriction.\n\nTraining will consist of treadmill walking at 40-50% of HRR for 32 minutes per session, 3 times per week for a total of 96 minutes per week.",[15],[30],{"name":31,"affiliation":32,"role":33},"Martin Senechal, PhD","Cardiometabolic Exercise & Lifestyle Laboratory, Fredericton, New Brunswick","PRINCIPAL_INVESTIGATOR",[35,39],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","506-451-6889","martin.senechal@unb.ca",{"name":40,"role":36,"phone":41,"phoneExt":42,"email":43},"Jamie Burr, PhD","519-824-4120","ext 52591","burrj@uoguelph.ca",[45,58,73],{"facility":46,"status":47,"city":48,"state":49,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":25,"geoPoint":25,"contacts":52},"Exercise Metabolism and Inflammation Laboratory","NOT_YET_RECRUITING","Okanagan","British Columbia","Canada","CA",[53,57],{"name":54,"role":36,"phone":55,"phoneExt":25,"email":56},"Jonathan Little, PhD","250-807-9876","jonathan.little@ubc.ca",{"name":54,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":59,"status":60,"city":61,"state":62,"zip":63,"country":50,"countryCode":51,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"Cardiometabolic Exercise & Lifestyle Laboratory","RECRUITING","Fredericton","New Brunswick","E3B5A3",{"type":65,"coordinates":66},"Point",[67,68],-66.66558,45.94541,{"lat":68,"lon":67},[71,72],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},{"name":31,"role":33,"phone":25,"phoneExt":25,"email":25},{"facility":74,"status":60,"city":75,"state":76,"zip":25,"country":50,"countryCode":51,"cosmosGeoPoint":77,"geoPoint":81,"contacts":82},"Human Performance & Health Research Laboratory","Guelph","Ontario",{"type":65,"coordinates":78},[79,80],-80.25599,43.54594,{"lat":80,"lon":79},[83,85],{"name":40,"role":36,"phone":41,"phoneExt":84,"email":43},"52591",{"name":40,"role":33,"phone":25,"phoneExt":25,"email":25},{"type":33,"investigatorFullName":87,"investigatorTitle":88,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Martin Senechal","Full Professor and Acting Assistant Dean of Graduate Studies",[90,92,94],{"name":91,"class":6},"Diabetes Canada",{"name":93,"class":6},"University of Guelph",{"name":95,"class":6},"University of British Columbia","100608039","feasibility-of-aerobic-exercise-with-blood-flow-restriction-training-in-people-living-with-type-2-diabetes-100608039",false,"NCT07196371","Feasibility of Aerobic Exercise With Blood Flow Restriction Training in People Living With Type 2 Diabetes","Testing the Feasibility of Blood Flow Restriction Training to Enhance the Health Benefits of Exercise in Individuals With Type 2 Diabetes: a Pilot Randomized Controlled Trial","BOOST-HEALTH","Inclusion Criteria:\n\n* Diagnosed with type 2 diabetes (5.7% \\\u003C HbA1c \\\u003C 9.0%)\n* Not regularly physically active (150 mins moderate-vigorous physical activity per week)\n\nExclusion Criteria:\n\n* Musculoskeletal issues preventing exercise training\n* Unstable medications over the last 3 months\n* Absolute contraindications to BFR (i.e. peripheral vascular disease)\n* A self-reported diagnosis of low iron concentrations, anemia, or being treated for these conditions\n* A diagnosis of any red blood cell-altering condition (i.e., sickle cell anemia, poikilocytosis)\n* Currently living with any cardiovascular disease, which would impact the ability to participate in exercise safely\n* Currently prescribed any medication which would impact the ability to use a heart rate monitor to accurately track intensity","ALL","19 Years","64 Years",{"count":108,"type":109},60,"ESTIMATED","INTERVENTIONAL",[112],"NA","The goal of this trial is to learn if blood flow restriction training with treadmill walking is possible for individuals living with type 2 diabetes. It will also learn about how the blood flow restriction with treadmill walking could improve health.\n\nThe main questions it aims to answer are:\n\nIs 6 weeks of treadmill walking with blood flow restriction reasonable for people with type 2 diabetes to perform? Does treadmill walking with blood flow restriction training help manage type 2 diabetes better than just treadmill walking?\n\nResearchers will compare treadmill walking with blood flow restriction to treadmill walking without blood flow restriction to see if blood flow restriction works to manage type 2 diabetes based on fitness and blood sugar levels.\n\nParticipants will:\n\nPerform treadmill walking with or without blood flow restriction for 96 minutes a week for 6 weeks.\n\nVisit the lab before and after the exercise for tests and questionnaires.",[115],"Type 2 Diabetes",[117,118,119,120,121,122,123,124],"Blood flow restriction","aerobic exercise","cardiorespiratory fitness","glycemia","feasability","physical activity","diabetes","continuious glucose monitor","2026-01-23",{"date":127,"type":128},"2026-01-26","ACTUAL",{"date":130,"type":128},"2026-01-01",{"date":132,"type":109},"2028-12",{"name":5,"class":6},3]