[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100505181":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":33,"responsibleParty":49,"collaborators":53,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":19,"eligibilityCriteria":62,"healthyVolunteers":59,"sex":63,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":19,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":19,"overallStatus":35,"whyStopped":19,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"University of Kentucky","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Time-restricted eating","EXPERIMENTAL","Participants will have baseline and post-study data collected, including activity\u002Fsleep data, metabolic parameters (fasting labs and anthropometric measurements), and cognitive testing. In addition, food timing will be collected throughout the study. Subjects will be educated about the potential health benefits of time-restricted eating and will self-select a 10-hr window, during which all daily calories will be consumed for 8 weeks.",[13],"Behavioral: Time-restricted eating",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"BEHAVIORAL","Subjects will be educated about the health benefits of time-restricted eating. Each subject will self-select a 10-hour (10hr +\u002F- 1 hr) window aligned with their active phase during which they will consume all daily calories. Subjects will text the time of their first and last daily calories for the duration of the study.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Julie Pendergast, PhD","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Matt Thomas, PhD","CONTACT","(859) 218-6770","jmthomg@uky.edu",{"name":31,"role":27,"phone":28,"phoneExt":19,"email":32},"Julie S Pendergast, PhD","julie.pendergast@uky.edu",[34],{"facility":5,"status":35,"city":36,"state":37,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Lexington","Kentucky","40536","United States","US",{"type":42,"coordinates":43},"Point",[44,45],-84.47772,37.98869,{"lat":45,"lon":44},[48],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"SPONSOR_INVESTIGATOR","Julie Pendergast","Associate Professor",[54],{"name":55,"class":56},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100505181","feasibility-of-implementing-time-restricted-eating-in-women-with-mild-cognitive-impairment-100505181",false,"NCT05858008","Feasibility of Implementing Time-restricted Eating in Women With Mild Cognitive Impairment","Inclusion Criteria:\n\n* Postmenopausal Women\n* Age 45-95\n* Diagnosis of mild cognitive impairment\n\nExclusion Criteria:\n\n* Individuals prone to hypoglycemia\n* Liver disease\n* Taking medications that affect eating behaviors\n* Alcohol consumption of \\>2 drinks per day\n* Significant circadian disruption\n* Having care-taking responsibilities that significantly affect sleep\n* Shift work or irregular lifestyle\n* Diagnosed clinical eating disorder\n* Participating in a formal weight loss program","FEMALE","45 Years","95 Years",{"count":67,"type":68},15,"ESTIMATED","INTERVENTIONAL",[71],"NA","This study will investigate the feasibility of implementing a time-restricted eating intervention in females with mild cognitive impairment. Targeted therapeutic interventions that improve cognitive impairment and delay onset of ADRD are particularly important for females, who have twice the lifetime risk of developing AD, compared to males.",[74],"Mild Cognitive Impairment","2025-12-24",{"date":77,"type":78},"2025-12-29","ACTUAL",{"date":80,"type":78},"2024-04-01",{"date":82,"type":68},"2026-06",{"name":51,"class":6},1]