[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556897":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":25,"locations":33,"responsibleParty":53,"collaborators":55,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":20,"enrollmentInfo":68,"targetDuration":20,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":36,"whyStopped":20,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"University of Alberta","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Prospective Surveillance for Trismus and Early Physical Therapy Intervention","EXPERIMENTAL","Weekly monitoring of mouth opening and jaw function. Early intervention if the participant presents with 5% or greater reduction in mouth opening compared to pre-treatment measures. Early intervention will comprise: physical therapy, home exercises and use of a jaw stretching device.",[13],"Behavioral: Early physical therapy intervention",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Early physical therapy intervention","Physical therapy including manual therapy, home exercises for the neck and jaw, and use of a jaw stretching device.",[9],null,[22],{"name":23,"affiliation":5,"role":24},"Margaret McNeely, PhD","PRINCIPAL_INVESTIGATOR",[26,30],{"name":23,"role":27,"phone":28,"phoneExt":20,"email":29},"CONTACT","780-492-6007","mmcneely@ualberta.ca",{"name":31,"role":27,"phone":28,"phoneExt":20,"email":32},"Lynn Mohamad, PhDc","frmace@ualberta.ca",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"University of Alberta\u002F Cross Cancer Institute","RECRUITING","Edmonton","Alberta","T6G 2G4","Canada","CA",{"type":43,"coordinates":44},"Point",[45,46],-113.46871,53.55014,{"lat":46,"lon":45},[49,51],{"name":23,"role":27,"phone":50,"phoneExt":20,"email":29},"780-248-1531",{"name":52,"role":24,"phone":20,"phoneExt":20,"email":20},"Margaret L. McNeely, PhD",{"type":54,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR",[56],{"name":57,"class":6},"Alberta Health services","100556897","feasibility-of-prospective-surveillance-and-early-physical-therapy-for-trismus-100556897",false,"NCT06531083","Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus","Feasibility of PRospective Surveillance and Early PhysiCal Therapy for TrIsmuS in Individuals With Head and Neck CancEr: A Single-Group Feasibility Trial (PRECISE)","PRECISE","Inclusion Criteria:\n\n* Have a diagnosis of oral, oropharyngeal, or nasopharyngeal cancer\n* Be scheduled to undergo cancer treatment that includes radiation therapy\n* Be able to read and understand English\n* Be an Alberta resident.\n\nExclusion Criteria:\n\n* Previous surgery for the temporomandibular joint that is not related to the HNC diagnosis.\n* Local cancer recurrence or metastatic disease.\n* Unable to provide informed consent.","ALL","18 Years",{"count":69,"type":70},30,"ESTIMATED","INTERVENTIONAL",[73],"NA","Trismus, or restricted jaw movement, can occur in individuals with head and neck cancer (HNC) undergoing surgery or radiation therapy. There is a paucity of research examining interventions for trismus. We aim to assess the feasibility of prospective surveillance and early intervention to mitigate trismus in individuals undergoing HNC treatment.\n\nMethod: The investigators will conduct a pilot single group feasibility study involving 30 individuals with HNC who will be undergoing radiation therapy. Participants will be identified at the HNC new patient clinic. Participants will be seen weekly during radiation therapy and will receive early intervention including manual therapy and a device-based jaw exercise regimen if presenting with 5% or greater reduction in jaw opening compared to pre-treatment.\n\nThe investigators will assess recruitment and completion rates, intervention acceptability, and data collection procedures. Descriptive statistics will summarize feasibility metrics and participant demographics. Findings will inform the design of a larger multicentre trial.",[76,77],"Head and Neck Cancer","Trismus",[79],"Physical Therapy","2026-04-03",{"date":82,"type":83},"2026-04-06","ACTUAL",{"date":85,"type":83},"2025-03-01",{"date":87,"type":70},"2026-08-31",{"name":5,"class":6},1]