[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642990":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":31,"responsibleParty":47,"collaborators":19,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":19,"eligibilityCriteria":56,"healthyVolunteers":52,"sex":57,"minAge":58,"maxAge":19,"enrollmentInfo":59,"targetDuration":19,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":19,"overallStatus":34,"whyStopped":19,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Sahlgrenska University Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"UP-A-AST Parent Group","EXPERIMENTAL","Participants receive the Unified Protocol-Adolescent Autism Parent Group (UP-A-AST), a parent-mediated, group-based cognitive behavioral intervention adapted for adolescents with autism spectrum disorder and co-occurring anxiety and\u002For depressive disorders. The intervention is delivered to parents in a group format and focuses on enhancing understanding of emotional difficulties and providing strategies to support adolescents' emotion regulation and functioning",[13],"Other: Unified Protocol-Adolescent Autism Parent Group (UP-A-AST)",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Unified Protocol-Adolescent Autism Parent Group (UP-A-AST)","The intervention is delivered in a group format to parents and focuses on strengthening parenting skills and promoting the adolescent's mental health and functional outcomes.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Karin Melin, PhD","PRINCIPAL_INVESTIGATOR",[25,29],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},"CONTACT","+46730494348","karin.a.melin@vgregion.se",{"name":5,"role":26,"phone":30,"phoneExt":19,"email":19},"+46313421000",[32],{"facility":33,"status":34,"city":35,"state":19,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":45},"BUP- Specialmottagning, Sahlgrenska University Hospital","RECRUITING","Gothenburg","41345","Sweden","SE",{"type":40,"coordinates":41},"Point",[42,43],11.96679,57.70716,{"lat":43,"lon":42},[46],{"name":22,"role":26,"phone":19,"phoneExt":19,"email":19},{"type":23,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Karin Melin","PhD","100642990","feasibility-study-of-up-a-ast-parent-group-for-adolescents-with-autism-and-co-occurring-anxietydepression-100642990",false,"NCT07637799","Feasibility Study of UP-A-AST Parent Group for Adolescents With Autism and Co-occurring Anxiety\u002FDepression","Unified Protocol-Adolescent Autism Parent Group (UP-A-AST) for Adolescents With Autism Spectrum Disorder and Co-occurring Anxiety and\u002For Depressive Disorders: A Feasibility Study","Inclusion Criteria:\n\n* Adolescents aged 12-17 years\n* Clinical diagnosis of autism spectrum disorder (ASD) according to DSM-IV, DSM-5, or ICD-10\n* Current diagnosis of anxiety disorder and\u002For depressive disorder according to DSM-5\n* Ongoing contact with a Child and Adolescent Psychiatry (BUP) outpatient clinic\n* Stable psychopharmacological treatment at the time of inclusion (if applicable)\n* Parents has participated in a psychoeducational program on autism within child and adolescent psychiatric services, or is assessed by the clinician to have equivalent knowledge\n\nExclusion Criteria:\n\n* Presence of a severe psychiatric disorder, such as psychotic disorder, bipolar disorder, or severe eating disorder\n* High suicide risk or suicide attempt within the past 12 months\n* Severe self-injurious behavior\n* Intellectual disability according to DSM-5\n* The adolescent is primarily in need of basic interventions for autism spectrum disorder\n* Parents are unable to attend all group sessions and\u002For lack the ability to engage in assigned home practice\n* Need for an interpreter","ALL","12 Years",{"count":60,"type":61},72,"ESTIMATED","INTERVENTIONAL",[64],"NA","Autism spectrum disorder (ASD) is associated with high rates of psychiatric comorbidity, particularly anxiety and depressive disorders, which contribute to significant impairment for affected youth and their families. Although cognitive behavioral therapy (CBT) is recommended as a first-line treatment for anxiety and depression in children and adolescents, there is a lack of evidence-based interventions specifically adapted for youth with ASD and co-occurring emotional disorders.\n\nThe Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents (UP-C\u002FUP-A) is a CBT-based intervention targeting shared mechanisms underlying anxiety and depression. A parent-mediated adaptation, the Unified Protocol-Adolescent Autism Parent Group (UP-A-AST), has been developed to address the specific needs of adolescents with ASD and co-occurring anxiety and\u002For depressive disorders. Preliminary quality improvement work has shown promising results.\n\nThis study aims to evaluate the feasibility, acceptability, and preliminary effects of the UP-A-AST Parent Group in a child and adolescent outpatient psychiatric setting. The study will include parents of adolescents aged 12-17 years with ASD and co-occurring anxiety and\u002For depressive disorders. Outcomes include changes in adolescents' psychiatric symptoms and functional impairment, as well as parents' perceived parenting competence. Additionally, parents' experiences of participating in the intervention will be explored.",[67,68,69],"Autistic Spectrum Disorder","Anxiety Disorders","Depressive Disorder","2026-06-09",{"date":72,"type":73},"2026-06-10","ACTUAL",{"date":75,"type":73},"2026-01-05",{"date":77,"type":61},"2027-03-30",{"name":5,"class":6},1]