[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100338697":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":11,"locations":20,"responsibleParty":48,"collaborators":11,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":11,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":11,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":11,"overallStatus":22,"whyStopped":11,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Hopital Foch","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Couple donor - recipient","EXPERIMENTAL",null,[13],"Procedure: Uterine transplantation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"PROCEDURE","Uterine transplantation","Uterine transplantation from living donor",[9],[21],{"facility":5,"status":22,"city":23,"state":11,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"RECRUITING","Suresnes","92150","France","FR",{"type":28,"coordinates":29},"Point",[30,31],2.22929,48.87143,{"lat":31,"lon":30},[34,39,41,44,46],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},"Jean-Marc Ayoubi, MD PhD","CONTACT","+33(0)146252339","jm.ayoubi@hopital-foch.org",{"name":35,"role":40,"phone":11,"phoneExt":11,"email":11},"PRINCIPAL_INVESTIGATOR",{"name":42,"role":43,"phone":11,"phoneExt":11,"email":11},"René Frydman, MD PhD","SUB_INVESTIGATOR",{"name":45,"role":43,"phone":11,"phoneExt":11,"email":11},"Marie Carbonnel, MD",{"name":47,"role":43,"phone":11,"phoneExt":11,"email":11},"Aurélie Revaux, MD",{"type":49,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100338697","feasibility-study-of-uterine-transplantation-from-living-donors-in-terms-of-efficacy-and-safety-in-patients-with-mayer-rokitansky-kster-hauser-syndrome-mrkh-100338697",false,"NCT03689842","Feasibility Study of Uterine Transplantation From Living Donors in Terms of Efficacy and Safety in Patients With Mayer-Rokitansky-Küster-Hauser Syndrome (MRKH)","Inclusion Criteria:\n\nGraft recipient is a patient with Mayer-Rokitansky-Küster-Hauser Type I Uterine Vaginal Agenesis (without renal, cardiac and bone malformations):\n\n* Being aged between 18 and 38 years old\n* In stable couple, with a pregnancy project, favorable psychological evaluation\n* No history of cancer and transfusion\n\nThe living donor is a woman related to the Graft recipient with\n\n* Absence of comorbidity (neurological, nephro-urological pathology, infectious, psychiatric or psychological pathology)\n* Absence of uterine surgery, abdomino-pelvic major pathology history\n\nExclusion Criteria:\n\nGraft recipient:\n\n* Extreme oligo-astheno-spermia and azoospermia in the husband\n* History of abdominopelvic surgery excluding uncomplicated appendectomy; vaginal residue not allowing anastomosis\n\nLiving donor :\n\n* Known thromboembolic risk factor\n* No Compatibility with the recipient (group, rhesus, HLA)",true,"FEMALE","18 Years","65 Years",{"count":61,"type":62},20,"ESTIMATED","INTERVENTIONAL",[65],"NA","In France, one in 4500 women is affected by the MayerRokitantskyKüsterHauser (MRKH) syndrome which is characterized by the absence of uterus at birth. Currently, the only solutions for these patients are:\n\n* Gestational surrogacy, prohibited in France\n* Adoption\n* Resignation\n\nUterine transplantation could become a good alternative.\n\nThis study is conducted in 10 patients with MRKH type I syndrome, who will be transplanted from a living donor uterus",[68],"Mayer Rokitansky Kuster Hauser Syndrome","2025-03-04",{"date":71,"type":72},"2025-03-07","ACTUAL",{"date":74,"type":72},"2017-12-14",{"date":76,"type":62},"2034-12-14",{"name":5,"class":6},1]