[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100585932":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":33,"locations":42,"responsibleParty":67,"collaborators":10,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":10,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":10,"enrollmentInfo":80,"targetDuration":10,"studyType":83,"phases":10,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":45,"whyStopped":10,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Tanta University","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"cirrhotic patients with esophageal varices",null,"52 cirrhotic patients with esophageal varices.",[13],"Diagnostic Test: fecal calprotectin",{"label":15,"type":10,"description":16,"interventionNames":17},"cirrhotic patients without esophageal varices","52 cirrhotic patients without esophageal varices.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"control group","52 healthy subjects as a control.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"DIAGNOSTIC_TEST","fecal calprotectin","fecal calprotectin test measures calprotectin protein in a stool sample. fecal calprotectin acts as a surrogate for gastrointestinal inflammation (e.g., inflammatory bowel disease, infectious gastroenteritis, acute appendicitis, peptic ulcer disease, coeliac disease, non-steroidal anti-inflammatory drugs (NSAID)-induced enteropathy)",[9,15,19],[29],{"name":30,"affiliation":31,"role":32},"Rania M Elkafoury, MD","Tropical medicine and infectious diseases Department, Faculty of Medicine, Tanta University","PRINCIPAL_INVESTIGATOR",[34,38],{"name":30,"role":35,"phone":36,"phoneExt":10,"email":37},"CONTACT","+201004672358","rania.elkafoury@med.tanta.edu.eg",{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},"Nabila A Elgazzar, MD","00201288585733","nabilaelgazzar@med.tanta.edu.eg",[43],{"facility":44,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Tanta University Hospitals","RECRUITING","Tanta","Gharbyea","31516","Egypt","EG",{"type":52,"coordinates":53},"Point",[54,55],31.00192,30.78847,{"lat":55,"lon":54},[58,62,63,66],{"name":59,"role":35,"phone":60,"phoneExt":10,"email":61},"Dina H Ziada, MD, head of department","00201117109990","dina.ziada@med.tanta.edu.eg",{"name":30,"role":32,"phone":10,"phoneExt":10,"email":10},{"name":64,"role":65,"phone":10,"phoneExt":10,"email":10},"Mennat-Allah M El Sawaf, MD","SUB_INVESTIGATOR",{"name":39,"role":65,"phone":10,"phoneExt":10,"email":10},{"type":32,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Rania Mamdouh Elkafoury","Lecturer of Tropical Medicine","100585932","fecal-calprotectin-for-prediction-of-esophageal-varices-in-cirrhotic-patients-100585932",false,"NCT06908798","Fecal Calprotectin for Prediction of Esophageal Varices in Cirrhotic Patients","The Accuracy of Fecal Calprotectin in Detecting Esophageal Varices in Egyptian Patients With Liver Cirrhosis","Inclusion Criteria:\n\n* Age ≥18 years\n* Liver cirrhosis\n\nExclusion Criteria:\n\n* Patients aged \\\u003C 18 years.\n* Inflammatory bowel disease.\n* Infectious gastroenteritis.\n* Malignancy.\n* Patients on proton pump inhibitors or NSAID.\n* Patients with spontaneous bacterial peritonitis.\n* Patients with hepatic encephalopathy.\n* Unwilling to participate in our study.",true,"ALL","18 Years",{"count":81,"type":82},156,"ESTIMATED","OBSERVATIONAL","The goal of this cross-sectional observational study is to evaluate the accuracy of fecal calprotectin versus non-invasive scores in assessing the presence and grading of esophageal varices in Egyptian patients.\n\nResearchers will compare fecal calprotectin levels in cirrhotic patients with and without esophageal varices (EVs) and healthy subjects. researchers will also evaluate the performance of fecal calprotectin, AST to platelet ratio index (APRI) score, fibrosis-4 (FIB-4) score, albumin-bilirubin (ALBI) score, platelet-albumin-bilirubin (PALBI) score, and platelet-spleen diameter ratio (PSR) for predicting esophageal varices.\n\nParticipants will undergo history-taking, clinical examination, laboratory investigations, fecal calprotectin, abdominal ultrasonography, and upper endoscopy. Endoscopic grading of esophageal varices will be done using Paquet's classification. The APRI, FIB-4, ALBI, PALBI, and PSR scores will be calculated. The performance of fecal calprotectin for predicting EVs will be compared versus other non-invasive scores.",[86],"Esophageal Varices",[88,89,90],"Fecal calprotectin","esophageal varices","liver cirrhosis","2025-03-27",{"date":93,"type":94},"2025-04-03","ACTUAL",{"date":96,"type":94},"2024-12-01",{"date":98,"type":82},"2025-12",{"name":5,"class":6},1]