[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100491321":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":46,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":50,"sex":54,"minAge":55,"maxAge":10,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Chinese PLA General Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Intracranial atherosclerosis and small vessel disease",null,"Patients diagnosed with intracranial large artery atherosclerosis and cerebral small vessel disease based on imaging screening.",[13],"Diagnostic Test: Magnetic resonance imaging",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DIAGNOSTIC_TEST","Magnetic resonance imaging","Imaging diagnostics mainly based on Magnetic resonance imaging.",[9],[21],{"name":22,"affiliation":5,"role":23},"Jinhao Lyu","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","+8615903562929","330322990@qq.com",[30],{"facility":5,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Beijing","Beijing Municipality","100853","China","CN",{"type":38,"coordinates":39},"Point",[40,41],116.39723,39.9075,{"lat":41,"lon":40},[44],{"name":45,"role":26,"phone":10,"phoneExt":10,"email":28},"Jinhao Lyu, MD",{"type":23,"investigatorFullName":22,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Attending physician","100491321","feedback-loop-between-intracranial-atherosclerosis-and-cerebral-small-vessel-disease-100491321",false,"NCT05677607","Feedback Loop Between Intracranial Atherosclerosis and Cerebral Small Vessel Disease","Inclusion Criteria:\n\n* Age ≥ 18 years\n* At least one intracranial artery ≥ 50% atherosclerotic stenosis\n* Modified Rankin Scale \\\u003C 2\n* Mini-mental State Examination \\> 24\n\nExclusion Criteria:\n\n* Concurrent ipsilateral extracranial artery ≥ 50% stenosis\n* Pregnant women\n* Contraindications to magnetic resonance examination (patients with pacemakers, nerve stimulators, artificial metal heart valves and other metal foreign bodies)","ALL","30 Years",{"count":57,"type":58},300,"ESTIMATED","OBSERVATIONAL","The present study aims at verifying the mutual effects between intracranial large artery atherosclerosis and cerebral small vessel disease on disease progression and prognosis by magnetic resonance imaging, and providing biomarkers for the early prevention and treatment of cerebrovascular disease.",[62,63],"ICAS - Intracranial Atherosclerosis","Cerebral Small Vessel Diseases",[65,66,67,68],"Intracranial atherosclerosis","Cerebral small vessel disease","Feedback mechanism","Multimodal MRI","2024-06-30",{"date":71,"type":72},"2024-07-03","ACTUAL",{"date":74,"type":72},"2023-01-01",{"date":76,"type":58},"2027-12-31",{"name":5,"class":6},1]