[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633261":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":34,"locations":41,"responsibleParty":70,"collaborators":25,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":25,"eligibilityCriteria":78,"healthyVolunteers":74,"sex":79,"minAge":80,"maxAge":25,"enrollmentInfo":81,"targetDuration":25,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":92,"overallStatus":43,"whyStopped":25,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Social Medical Corporation Daiyukai","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Femoral Triangle Block (FTB) Group","EXPERIMENTAL","Ultrasound-guided femoral triangle block with standardized multimodal analgesia including popliteal plexus block.",[13],"Procedure: Femoral Triangle Block (FTB) Group",{"label":15,"type":16,"description":17,"interventionNames":18},"Adductor Canal Block (ACB) Group","ACTIVE_COMPARATOR","Ultrasound-guided adductor canal block with standardized multimodal analgesia including popliteal plexus block.",[19],"Procedure: Adductor Canal Block (ACB) Group",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Ultrasound-guided femoral triangle block performed as part of a standardized multimodal analgesia protocol for total knee arthroplasty.\n\nA total of 10 mL of 0.25% levobupivacaine is injected in the femoral triangle to achieve sensory blockade of the saphenous nerve, the nerve to vastus medialis, and surrounding structures.\n\nThe injection is performed at the distal femoral triangle under ultrasound guidance, targeting the perineural space adjacent to the relevant nerve branches.\n\nIn all participants, a popliteal plexus block using 15 mL of 0.25% levobupivacaine is additionally performed to standardize posterior knee analgesia.",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Ultrasound-guided adductor canal block performed as part of a standardized multimodal analgesia protocol for total knee arthroplasty.\n\nA total of 10 mL of 0.25% levobupivacaine is administered in a divided manner within the proximal adductor canal, targeting both the saphenous nerve within the canal and the nerve to vastus medialis running adjacent to the canal.\n\nThe injection is performed under ultrasound guidance to achieve selective sensory blockade while minimizing motor involvement.\n\nIn all participants, a popliteal plexus block using 15 mL of 0.25% levobupivacaine is additionally performed to standardize posterior knee analgesia.",[15],[30],{"name":31,"affiliation":32,"role":33},"Norihiro Sakai, MD, PhD","Department of Anesthesiology, Daiyukai General Hospital","PRINCIPAL_INVESTIGATOR",[35,39],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","+81-586-72-1211","dykmasui@gmail.com",{"name":40,"role":36,"phone":37,"phoneExt":25,"email":38},"Tomohiro Michino, MD, PhD",[42],{"facility":32,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Ichinomiya","Aichi-ken","491-8511","Japan","JP",{"type":50,"coordinates":51},"Point",[52,53],136.8,35.3,{"lat":53,"lon":52},[56,57,58,60,62,64,66,68],{"name":31,"role":36,"phone":37,"phoneExt":25,"email":38},{"name":40,"role":36,"phone":37,"phoneExt":25,"email":38},{"name":40,"role":59,"phone":25,"phoneExt":25,"email":25},"SUB_INVESTIGATOR",{"name":61,"role":59,"phone":25,"phoneExt":25,"email":25},"Aya Seki, MD",{"name":63,"role":59,"phone":25,"phoneExt":25,"email":25},"Chieko Taruishi, MD",{"name":65,"role":59,"phone":25,"phoneExt":25,"email":25},"Yuki Uematsu, MD",{"name":67,"role":59,"phone":25,"phoneExt":25,"email":25},"Tomoko Sudani, MD",{"name":69,"role":59,"phone":25,"phoneExt":25,"email":25},"Hiroki Yoshida, MS",{"type":71,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100633261","femoral-triangle-block-vs-adductor-canal-block-on-early-quadriceps-function-after-total-knee-arthroplasty-100633261",false,"NCT07524387","Femoral Triangle Block vs Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty","Postoperative Effects of Femoral Triangle Block Versus Adductor Canal Block on Early Quadriceps Function After Total Knee Arthroplasty Under a Multimodal Analgesia Protocol: A Randomized Double-Blind Controlled Trial","Inclusion Criteria:\n\n1. Adult patients (≥ 20 years of age) are scheduled to undergo primary unilateral TKA.\n2. American Society of Anesthesiologists (ASA) physical status I-III.\n3. Ability to ambulate independently prior to surgery.\n4. Ability to understand the study procedures and provide written informed consent.\n5. Planned perioperative anesthesia management including regional anesthesia as part of standard clinical care.\n6. Ability to extend the knee below 30 degrees preoperatively (no knee extension contracture)\n\nExclusion Criteria:\n\n1. Known allergy or contraindication to local anesthetic agents used in this study.\n2. Pre-existing neurological or neuromuscular disorders affect lower limb strength or motor control.\n3. Severe cognitive impairment or psychiatric conditions interfere with study participation or assessment.\n4. History of revision knee arthroplasty on the operative side.\n5. Severe preoperative quadriceps weakness that precludes reliable baseline strength assessment.\n6. Any condition deemed by the investigator to make participation inappropriate.","ALL","20 Years",{"count":82,"type":83},136,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this clinical trial is to compare the effects of femoral triangle block (FTB) and adductor canal block (ACB) on early quadriceps function after total knee arthroplasty (TKA).\n\nThe main question it aims to answer is whether FTB causes more early quadriceps functional impairment than ACB under a standardized multimodal analgesia protocol.\n\nResearchers will compare FTB and ACB using a composite binary functional outcome measured 6 hours after block completion. Quadriceps functional impairment is defined as the inability to perform a structured straight leg raise or quadriceps muscle strength \\\u003C50% of the preoperative baseline.\n\nParticipants will be randomly assigned to receive ultrasound-guided FTB or ACB. All participants will also receive a popliteal plexus block and standardized multimodal analgesia.",[89,90,91],"Total Knee Arthroplasty","Total Knee Arthroplasty Recovery","Total Knee Arthroplasty Postoperative Pain",[93,89,94,95],"Postoperative Pain","Peripheral Nerve Block","Postoperative Recovery","2026-04-13",{"date":98,"type":99},"2026-04-16","ACTUAL",{"date":96,"type":99},{"date":102,"type":83},"2029-03-31",{"name":5,"class":6},1]