[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100513258":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":18,"centralContacts":22,"locations":29,"responsibleParty":57,"collaborators":10,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":10,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"University Hospital Ostrava","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with hypertension, resistant hypertension, and secondary hypertension",null,"Patients with arterial hypertension, resistant arterial hypertension, and secondary hypertension.",[13],"Other: No intervention.",[15],{"type":6,"name":16,"description":16,"armGroupLabels":17,"otherNames":10},"No intervention.",[9],[19],{"name":20,"affiliation":5,"role":21},"Zdeněk Ramík, MD","PRINCIPAL_INVESTIGATOR",[23],{"name":24,"role":25,"phone":26,"phoneExt":27,"email":28},"Jiří Hynčica","CONTACT","0042059737","2587","jiri.hyncica@fno.cz",[30],{"facility":31,"status":32,"city":33,"state":34,"zip":35,"country":36,"countryCode":10,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"University Hospital Ostrava, - Department of Internal Medicine and Cardiology","RECRUITING","Ostrava","Czech Republic","70852","Czechia",{"type":38,"coordinates":39},"Point",[40,41],18.28204,49.83465,{"lat":41,"lon":40},[44,45,46,49,51,53,55],{"name":24,"role":25,"phone":26,"phoneExt":27,"email":28},{"name":20,"role":21,"phone":10,"phoneExt":10,"email":10},{"name":47,"role":48,"phone":10,"phoneExt":10,"email":10},"Iveta Bystroňová, MSc","SUB_INVESTIGATOR",{"name":50,"role":48,"phone":10,"phoneExt":10,"email":10},"Janula Stromská, MD",{"name":52,"role":48,"phone":10,"phoneExt":10,"email":10},"Pavla Jadrníčková, MD",{"name":54,"role":48,"phone":10,"phoneExt":10,"email":10},"Lukáš Štos, MD",{"name":56,"role":48,"phone":10,"phoneExt":10,"email":10},"Eva Široká",{"type":58,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100513258","fetuin-a-as-a-predictor-of-deterioration-of-renal-function-in-hypertonic-patients-100513258",false,"NCT05963126","Fetuin A as a Predictor of Deterioration of Renal Function in Hypertonic Patients","Modified Urine Fetuin A as a Predictor of Deterioration of Renal Function in Patients With Resistant and Non-resistant Hypertension","Inclusion Criteria:\n\n* Arterial hypertension treated by at least one antihypertensive agent\n\nExclusion Criteria:\n\n* Diabetes mellitus of any type, defined as fasting glucose \\>7,0 mmol\u002Fl or any glycemia \\>11,0 mmol\u002Fl, or HbA1c\\>48 mmol\u002Fmol\n* Decompensated arterial hypertension defined as office blood pressure \\>180\u002F110 mmHg or on Ambulatory Blood Pressure Monitoring (ABPM)\n* Patient with renal replacement therapy\n* Present rheumatoid disease (rheumatoid arthritis, systemic lupus, sclerodermia, dermatomyositis, Inflammatory Bowel Disease, etc.), positivity of antinuclear antibody (ANA) \u002F extractable nuclear antigen (ENA) screening\n* Acute infection defined as C-Reactive Protein (CRP) \\>50 mg\u002Fl\n* Severe impairment of liver function defined as cirrhosis, Alanine Transaminase or ASpartate Transferase (ALT or AST) \\>10 µkat\u002Fl\n* Terminal incurable illness","ALL","18 Years","100 Years",{"count":70,"type":71},200,"ESTIMATED","OBSERVATIONAL","Commonly used parameters (creatinine, estimated glomerular filtration rate, and urine albumin\u002Fcreatinine ratio) for prediction of decline of renal function are sensitive for advanced kidney impairment. Modified human urine Fetuin A (urine Fetuin A) with specific modification in urine (Fetuin A) can earlier predict the progression of kidney disease in patients with diabetes. Studies evaluating urine Fetuin A in hypertonic patients are still lacking.",[75],"Arterial Hypertension",[75,77,78,79,80],"Resistant Arterial Hypertension","Chronic Kidney Disease","Fetuin A","DNLite IVD103","2023-07-18",{"date":83,"type":84},"2023-07-27","ACTUAL",{"date":86,"type":84},"2023-07-01",{"date":88,"type":71},"2026-12-31",{"name":5,"class":6},1]