[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100592499":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":30,"responsibleParty":47,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":10,"overallStatus":33,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"RenJi Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Acute myocardial infarction-associated ventricular aneurysm",null,"Participants in this group are patients diagnosed with a ventricular aneurysm secondary to acute myocardial infarction (AMI). Diagnosis of AMI is based on clinical presentation, elevated cardiac biomarkers, ECG changes, and coronary angiogram. Ventricular aneurysm is mainly diagnosed by imaging modalities such as echocardiography and cardiovascular magnetic resonance (CMR).",[13],"Diagnostic Test: 18F FAPI-42 PET\u002FCT scan",{"label":15,"type":10,"description":16,"interventionNames":17},"Acute myocardial infarction without evidence of ventricular aneurysm","Participants in this group are patients diagnosed with AMI only. Diagnosis of AMI is based on clinical presentation, elevated cardiac biomarkers, ECG changes, and coronary angiogram. Echocardiography or CMR does not identify a ventricular aneurysm.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"DIAGNOSTIC_TEST","18F FAPI-42 PET\u002FCT scan","During the hospital stay, participants will receive an 18F FAPI-42 PET\u002FCT scan. 18F FAPI-42 is a new fibroblast activation protein (FAP)-specific tracer used for fibrosis imaging. PET\u002FCT will be performed using the ultra-high-resolution digital PET\u002FCT uEXPLORER (United Imaging, Shanghai, China)",[15,9],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"ZHIGUO ZOU, MD, PhD","CONTACT","13524596108","zouzhiguo@renji.com",[31],{"facility":32,"status":33,"city":34,"state":10,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Renji Hospital","RECRUITING","Shanghai","200127","China","CN",{"type":39,"coordinates":40},"Point",[41,42],121.45806,31.22222,{"lat":42,"lon":41},[45],{"name":26,"role":27,"phone":46,"phoneExt":10,"email":29},"+86 13524596108",{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Zhiguo Zou","Doctor","100592499","fibrosis-assessment-in-myocardial-infarction-associated-ventricular-aneurysm-100592499",false,"NCT06994221","Fibrosis Assessment in Myocardial Infarction-associated Ventricular Aneurysm","Assessment of Myocardial Fibrosis by 18F-FAPI\u002FPET-CT in Patients With Myocardial Infarction-associated Ventricular Aneurysm","Inclusion Criteria:\n\n* Aged 18-75 years old\n* Diagnosed with STEMI or NSTEMI (ACC\u002FAHA guidelines)\n* Half male and half female\n* Undergo CAG and PCI treatment;\n* Receive either echocardiography or CMR to identify a ventricular aneurysm;\n* Written informed consent\n\nExclusion Criteria:\n\n* Patients under the age of 18 years old;\n* Patients who are pregnant\u002Fbreastfeeding;\n* Patients who has a previous history of allergy to radio tracers.","ALL","18 Years","75 Years",{"count":62,"type":63},20,"ESTIMATED","OBSERVATIONAL","The study will use 18F-FAPI PET\u002FCT to study myocardial fibrosis in patients diagnosed with myocardial infarction-associated ventricular aneurysm (MI-VA). Participants will receive the PET\u002FCT scan during hospital stay, as well as serial echocardiography and telephonic follow-ups. Analysed will focus on the characterization of myocardial fibrosis and its correlations with the clinical prognosis in the patients.",[67,68,69],"Acute Myocardial Infarction","Ventricular Aneurysm Following Acute Myocardial Infarction","Myocardial Fibrosis","2025-05-20",{"date":72,"type":73},"2025-05-29","ACTUAL",{"date":75,"type":73},"2024-11-01",{"date":77,"type":63},"2025-12-31",{"name":5,"class":6},1]