[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100548067":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":19,"centralContacts":24,"locations":36,"responsibleParty":49,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":53,"sex":59,"minAge":60,"maxAge":10,"enrollmentInfo":61,"targetDuration":10,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":10,"overallStatus":70,"whyStopped":10,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Guy's and St Thomas' NHS Foundation Trust","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Retrospective",null,"All participants will be in one group which is the collection of retrospective data",[13],"Other: Prospective",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Prospective","Collection of prospective data all ready available for participant",[9],[20],{"name":21,"affiliation":22,"role":23},"Alex West, MBBS","Guys and St. Thomas NHS Foundation Hospital","PRINCIPAL_INVESTIGATOR",[25,31],{"name":26,"role":27,"phone":28,"phoneExt":29,"email":30},"Alexandra Lawrence, MBBS","CONTACT","02071887188","58207","alexandra.lawrence@gstt.nhs.uk",{"name":32,"role":27,"phone":33,"phoneExt":34,"email":35},"Gillian Radcliffe, BSc","07395285492","88070","gillian.radcliffe@gstt.nhs.uk",[37],{"facility":38,"status":10,"city":39,"state":10,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":10},"Guy's & St Thomas' NHS Foundation Trust","London","SE1 9RT","United Kingdom","UK",{"type":44,"coordinates":45},"Point",[46,47],-0.12574,51.50853,{"lat":47,"lon":46},{"type":50,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100548067","fibrotic-interstitial-lung-disease-with-nocturnal-hypoxaemia-and-exercise-induced-desaturation-100548067",false,"NCT06416163","FIBRotic Interstitial Lung Disease With Nocturnal hypOXaemia and EXercise Induced desaTuRAtion","A Prospective Observational Study Investigating Whether Nocturnal Hypoxaemia and Exercise Induced Desaturation Predict Functional Deterioration in Patients With Fibrotic Interstitial Lung Disease","FIBRINOX-EXTRA","Inclusion Criteria:\n\n1. Patients aged 18 year and over\n2. Tertiary MDT diagnosis of FILD with \\>10% fibrosis on CT chest as determined by the investigator. Underlying diagnoses to include but not limited to: idiopathic pulmonary fibrosis (IPF), non-specific interstitial pneumonitis (NSIP), chronic hypersensitivity pneumonitis (CHP), connective tissue disease-related interstitial lung disease (CTD-ILD), fibrotic organising pneumonia (FOP) and pulmonary sarcoidosis.\n3. Able to provide informed written consent\n\nExclusion Criteria:\n\n1. The use of or any indication for long-term oxygen therapy (LTOT)\n2. Known moderate or severe obstructive sleep apnoea with an apnoea\u002Fhypopnoea index (AHI) or oxygen desaturation index (ODI) over 15 events per hour\n3. Radiological predominance of emphysema compared with fibrosis on CT chest\n4. Inability to complete all health status questionnaires as set out in this protocol, with appropriate support\n5. A confirmed diagnosis of pulmonary hypertension\n6. Significant cardiovascular comorbidity including severe, uncontrolled hypertension, uncontrolled arrhythmia, recent acute coronary syndrome within 30 days prior to study enrolment, that could mean exercise testing poses a risk to patient health, in the opinion of the investigator\n7. Musculoskeletal comorbidity that will preclude the participant's ability to reliably complete the complete 6-minute walk test (6MWT)\n8. Participation in another research project which may confound this study's research findings","ALL","18 Years",{"count":62,"type":63},160,"ESTIMATED","OBSERVATIONAL","This is an observational clinical research study investigating patients with fibrotic interstitial lung disease (fILD), also known as pulmonary fibrosis.\n\nIt is not known why some patients with fILD clinically deteriorate. This study will investigate whether measuring oxygen levels during sleep or exercise can help identify patients who are at increased risk of clinical deterioration.",[67,68,69],"Interstitial Lung Disease","Fibrosis Lung","Pulmonary Hypertension","NOT_YET_RECRUITING","2024-07-05",{"date":73,"type":74},"2024-07-08","ACTUAL",{"date":76,"type":63},"2024-07-01",{"date":78,"type":63},"2029-07-01",{"name":5,"class":6},1]