[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100570774":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":28,"centralContacts":32,"locations":43,"responsibleParty":63,"collaborators":23,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":23,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":45,"whyStopped":23,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8,14],{"label":9,"type":6,"description":10,"interventionNames":11},"Intervention Diet First, then Control Diet","Participants will complete \\~4 weeks of the Intervention Diet, followed by a washout period of at least 4 weeks, then \\~4 weeks of the Control Diet. At the end of each Diet period, participants will undergo a 2 hour controlled wood smoke exposure, following which outcome measures will be assessed.",[12,13],"Other: Intervention Diet","Other: Control Diet",{"label":15,"type":6,"description":16,"interventionNames":17},"Control Diet First, then Intervention Diet","Participants will complete \\~4 weeks of the Control Diet, followed by a washout period of at least 4 weeks, then \\~4 weeks of the Intervention Diet. At the end of each Diet period, participants will undergo a 2 hour controlled wood smoke exposure, following which outcome measures will be assessed.",[12,13],[19,24],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":23},"Intervention Diet","Designed to increase Omega-3 Fatty Acids (Eicosapentaenoic acid (EPA), Docosahexaenoic acid (DHA)), fruit, and vegetable intake, participants will receive grocery and meal deliveries for approximately 4-weeks via online ordering with dietician counselling.",[15,9],null,{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":23},"Control Diet","Participants will receive weekly food subsidies for their groceries for 4-weeks (\\~equivalent to the subsidies to provide groceries in the Intervention arm) but are free to purchase whatever they wish. The participants will continue to have dietician counseling during this time.",[15,9],[29],{"name":30,"affiliation":5,"role":31},"Emily Brigham, MD","PRINCIPAL_INVESTIGATOR",[33,39],{"name":34,"role":35,"phone":36,"phoneExt":37,"email":38},"Agustin Bueso","CONTACT","604-875-4111","21721","agustin.bueso@ubc.ca",{"name":40,"role":35,"phone":36,"phoneExt":41,"email":42},"Agnes Yuen","66455","agnes.yuen@ubc.ca",[44],{"facility":5,"status":45,"city":46,"state":47,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Vancouver","British Columbia","V5Z 1M9","Canada","CA",{"type":52,"coordinates":53},"Point",[54,55],-123.11934,49.24966,{"lat":55,"lon":54},[58,61],{"name":59,"role":35,"phone":36,"phoneExt":60,"email":38},"Agustin Bueso, BSc","23177",{"name":62,"role":35,"phone":36,"phoneExt":41,"email":42},"Agnes CY Yuen, BSc",{"type":31,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Emily Brigham","Associate Professor","100570774","fire-diet-food-as-an-intervention-to-reduce-the-effects-of-woodsmoke-exposure-on-respiratory-health-100570774",false,"NCT06711614","FIRE-Diet: Food as an Intervention to Reduce the Effects of Woodsmoke Exposure on Respiratory Health","FIRE-Diet-M","Inclusion Criteria:\n\n* Healthy, and specifically with no respiratory disease\n* Not taking any supplements, or willing to abstain from supplement use for 4-weeks prior to study start and the whole duration of the study,\n* Must currently consume, on average, less than 2 servings of fish per week and fewer than 5 servings of fruits and vegetables per day based on screening questionnaires.\n* Must have a null GSTM1 genotype determined at screening.\n* Must be able to provide a sufficient sputum sample during the screening visit.\n\nExclusion Criteria:\n\n* Pregnant or planning to become pregnant during the study period.\n* Health conditions that would pose an unacceptable risk of dietary change, or conditions that are uncontrolled based on principal investigator's judgement.\n* Actively attempting to lose weight.\n* Frequent wood smoke exposure (e.g. at home or employment).\n* Unable to store provided meals and food safely.\n* Food allergies\u002Fintolerance or food aversion preventing adherence to the intervention diet, or unwillingness\u002Fmedically unable to adjust diet in line with the intervention.\n* Relocation during the study period to an area which will prevent food delivery.\n* History of smoking tobacco, marijuana, or and other substance or vaping within the past 6 months, or having smoked the equivalent of 0.5 pack-years ever.\n* Body mass index (BMI) \\\u003C18.5, as determined during the in-person screening visit.",true,"ALL","19 Years","40 Years",{"count":78,"type":79},48,"ESTIMATED","INTERVENTIONAL",[82],"NA","Research suggests that consuming more fatty fish, fruits, and vegetables could potentially shield the lungs from the negative impacts of air pollution. The research team will look at whether a dietary intervention aimed at increasing intake of these foods can protect the lungs from woodsmoke as the air pollutant and look into how this works.",[85],"Healthy Individuals",[87,88,89,90],"Diet Intervention","EPA","DHA","Omega-3 fatty acids","2026-02-11",{"date":93,"type":94},"2026-02-13","ACTUAL",{"date":96,"type":94},"2025-06-17",{"date":98,"type":79},"2029-12-31",{"name":5,"class":6},1]