[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100441240":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":28,"locations":36,"responsibleParty":56,"collaborators":10,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":60,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":10,"studyType":72,"phases":10,"briefSummary":73,"conditions":74,"keywords":79,"overallStatus":39,"whyStopped":10,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Masonic Cancer Center, University of Minnesota","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Case",null,"Adolescent or young adult acute lymphoblastic leukemia survivor, OR living with chronic lung disease of prematurity, OR living with heart transplant",[13],"Other: Physical activity",{"label":15,"type":10,"description":16,"interventionNames":17},"Control","14-25 years old healthy individuals who are ambulatory without assistance. We may enroll younger subjects but we wish to subjects to match our patient population",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Physical activity","Participant Reported Physical Activity and Outcomes (completed via REDCap or on paper)",[9,15],[24],{"name":25,"affiliation":26,"role":27},"Pianosi Paolo, MD","Masonic Children's Hospital, University of Minnesota","PRINCIPAL_INVESTIGATOR",[29,34],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Char Napurski, MPH, CCRP","CONTACT","612-626-2140","bake0257@umn.edu",{"name":25,"role":31,"phone":10,"phoneExt":10,"email":35},"ppianosi@umn.edu",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Masonic Cancer Center","RECRUITING","Minneapolis","Minnesota","55455","United States","US",{"type":46,"coordinates":47},"Point",[48,49],-93.26384,44.97997,{"lat":49,"lon":48},[52],{"name":53,"role":31,"phone":54,"phoneExt":10,"email":55},"Lucie Turcotte, MD, MPH, MS","612-624-1818","turc0023@umn.edu",{"type":57,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100441240","fitness-and-lung-function-among-survivors-of-heart-transplant-leukemia-and-infant-bpd-through-exercise-100441240",false,"NCT05025774","Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise","Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant Bronchopulmonary Dysplasia (BPD, Also Known as Chronic Lung Disease of Prematurity) Through Exercise (FLASHLITE)","FLASHLITE","Inclusion Criteria:\n\n* Cases:\n\n  * Acute lymphoblastic leukemia survivor, OR living with chronic lung disease of prematurity, OR living with heart transplant\n  * 8-25 years old\n  * Height: ≥ 48 inches\n  * Ambulatory without assistance\n  * English speaking\n  * Normotensive (\\\u003C95th percentile for age; okay if managed with antihypertensive medication)\n  * SpO2 \\>92%\n  * Not pregnant\n  * ALL survivor specific: must have completed therapy ≥ 3 months prior to study entry\n* Controls\n\n  * 8-25 years old\n  * Height: ≥ 48 inches\n  * Ambulatory without assistance\n  * English speaking\n  * No history of arrhythmia or known cardiac dysfunction at baseline\n  * Normotensive (\\\u003C95th percentile for age; okay if managed with antihypertensive medication)\n  * SpO2 \\>95%\n  * Not pregnant\n\nExclusion Criteria:\n\n* Cases:\n\n  * ALL specific: received cranial radiation, bone marrow transplant recipients\n  * Investigator or patient's primary physician deems the patient unsuitable for the study\n* Controls:\n\n  * History of malignancy, CLD or HT or any other diagnosis which may reduce cardiorespiratory function\n  * Investigator deems the patient unsuitable for the study","ALL","8 Years","25 Years",{"count":70,"type":71},90,"ESTIMATED","OBSERVATIONAL","This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))",[75,76,77,78],"Chronic Lung Disease","Chronic Obstructive Pulmonary Disease","Acute Lymphoblastic Leukemia","Heart Transplant",[80,81,82,83],"Quality of life","Lung function","Fitness","Exercise","2025-11-21",{"date":86,"type":87},"2025-11-24","ACTUAL",{"date":89,"type":87},"2025-03-14",{"date":91,"type":71},"2026-12-01",{"name":5,"class":6},1]