[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565924":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":10,"responsibleParty":42,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":10,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":69,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":10},{"fullName":5,"class":6},"Istanbul University - Cerrahpasa","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Pediatric-Onset Multiple Sclerosis Group",null,"Individuals in the POMS group will be evaluated in terms of lower extremity muscle strength, physical activity, exercise capacity, balance, quality of life, and fatigue.",[13],"Other: Evaluation of lower extremity muscle strength, physical activity, exercise capacity, balance, quality of life, and fatigue in POMS",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy Controls","Individuals in the control group will be evaluated in terms of lower extremity muscle strength, physical activity, exercise capacity, balance, quality of life, and fatigue.",[18],"Other: Evaluation of lower extremity muscle strength, physical activity, exercise capacity, balance, quality of life, and fatigue in healthy controls",[20,24],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"Evaluation of lower extremity muscle strength, physical activity, exercise capacity, balance, quality of life, and fatigue in POMS","The demographic information of the patients will be taken with the form prepared for the people in this group. Patients will be assessed using the FTSTS test to evaluate lower extremity muscle strength, the Godin Leisure Time Exercise Questionnaire (GLTEQ) for physical activity, the 2-Minute Walk Test (2MWT) for exercise capacity, the Timed Up and Go (TUG) Test for functional mobility, the Pediatric Quality of Life Inventory (PedsQL) for quality of life, and the PedsQL Multidimensional Fatigue Scale for fatigue. All assessments will be completed on the same day and will not be repeated after a certain period of time.",[9],{"type":6,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"Evaluation of lower extremity muscle strength, physical activity, exercise capacity, balance, quality of life, and fatigue in healthy controls","The demographic information of the healthy controls will be taken. Healthy controls will be assessed using the FTSTS test to evaluate lower extremity muscle strength, the Godin Leisure Time Exercise Questionnaire (GLTEQ) for physical activity, the 2-Minute Walk Test (2MWT) for exercise capacity, the Timed Up and Go (TUG) Test for functional mobility, the Pediatric Quality of Life Inventory (PedsQL) for quality of life, and the PedsQL Multidimensional Fatigue Scale for fatigue. All assessments will be completed on the same day and will not be repeated after a certain period of time.",[15],[29],{"name":30,"affiliation":5,"role":31},"Serhat Güler MD","STUDY_CHAIR",[33,38],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Yonca Zenginler Yazgan PhD","CONTACT","+905326006294","yoncazenginler@gmail.com",{"name":39,"role":35,"phone":40,"phoneExt":10,"email":41},"Zelal Apaydın MSc","+905395583859","apaydinzelal@gmail.com",{"type":43,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Yonca Zenginler Yazgan","Associate Professor","100565924","five-times-sit-to-stand-test-for-patients-with-pediatric-onset-multiple-sclerosis-100565924",false,"NCT06648499","Five Times Sit-To-Stand Test for Patients with Pediatric-Onset Multiple Sclerosis","Five Times Sit-To-Stand Test for Patients with Pediatric-Onset Multiple Sclerosis: Performance and Explanatory Factors","Inclusion Criteria:\n\n* Volunteer to participate\n* Being diagnosed with pediatric onset multiple sclerosis\n* Being between the ages of 15-22\n* EDSS ≤6\n\nExclusion Criteria:\n\n* Having another diagnosis in addition to the diagnosis of pediatric-onset multiple sclerosis\n* Having had an attack or received corticosteroid treatment 3 months before participating in the study",true,"ALL","15 Years","22 Years",{"count":58,"type":59},46,"ESTIMATED","OBSERVATIONAL","Transitioning from a sitting to a standing position is a movement essential for maintaining physical independence and functional mobility, and is necessary for performing many activities in daily life. Lower extremity muscle strength is considered the most critical factor reducing the capacity to perform the sit-to-stand movement. A study concluded that the Five-Times Sit-to-Stand test in patients with multiple sclerosis (MS) is multifactorial and is associated with walking speed and fatigue. Another study using the same test concluded that lower extremity capacity is reduced compared to healthy controls and is associated with balance, functional mobility, gait, and fatigue.\n\nPediatric-onset MS, occurring in patients under the age of 18, accounts for approximately 3-10% of all multiple sclerosis cases and is increasingly recognized in many parts of the world. According to our research, no studies have been found that demonstrate the extent of lower extremity involvement in patients with pediatric-onset MS compared to their healthy controls. Our aim is to evaluate the performance of the Five-Times Sit-to-Stand test in patients with pediatric-onset MS, compare it with healthy controls, and examine its relationship with physical activity, exercise capacity, functional mobility, quality of life and fatigue.",[63],"Pediatric-Onset Multiple Sclerosis (POMS)",[65,66,67,68],"lower extremity muscle strength","pediatric-onset multiple sclerosis","five times sit-to-stand test","physiotherapy","NOT_YET_RECRUITING","2024-10-18",{"date":72,"type":73},"2024-10-22","ACTUAL",{"date":75,"type":59},"2024-10-28",{"date":77,"type":59},"2024-12-16",{"name":5,"class":6}]