[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100523107":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":33,"responsibleParty":58,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":68,"sex":69,"minAge":70,"maxAge":10,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":10,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"Ottawa Heart Institute Research Corporation","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Acute atherosclerotic disease event group",null,"Patients with a recent ACS (i.e. STEMI or NSTEMI), stroke or transient ischemic attack.",[13],"Procedure: [18F]-Florbetaben PET and CT imaging",{"label":15,"type":10,"description":16,"interventionNames":17},"Control","A control population of patients with known vascular disease but without recent ACS, stroke\u002FTIA.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","[18F]-Florbetaben PET and CT imaging","\\[18F\\]-Florbetaben imaging to compare uptake in the culprit and non-culprit arteries.",[9,15],[25],{"name":26,"affiliation":5,"role":27},"Kevin E Boczar, MD","PRINCIPAL_INVESTIGATOR",[29],{"name":26,"role":30,"phone":31,"phoneExt":10,"email":32},"CONTACT","6132821835","kboczar@ottawaheart.ca",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"University of Ottawa Heart Institute","RECRUITING","Ottawa","Ontario","K1Y 4W7","Canada","CA",{"type":43,"coordinates":44},"Point",[45,46],-75.69812,45.41117,{"lat":46,"lon":45},[49,54],{"name":50,"role":30,"phone":51,"phoneExt":52,"email":53},"Chantal L","6136967000","18817","clefebvre@ottawaheart.ca",{"name":55,"role":30,"phone":51,"phoneExt":56,"email":57},"Poppy M","14646","pmacphee@ottawaheart.ca",{"type":59,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100523107","florbetaben-for-imaging-of-vascular-amyloid-100523107",false,"NCT06091319","Florbetaben for Imaging of Vascular Amyloid","Florbetaben for Imaging of Vascular Amyloid: Evaluation of Amyloid Inflammasome Imaging in Carotid and Coronary Arteries in Patients With Unstable Atherosclerosis- A Pilot Study","FERMATA","Inclusion Criteria:\n\n1. suffered a recent cardiovascular event (30-120 days post ACS (i.e. STEMI or NSTEMI) or TIA\u002Fstroke with ipsilateral large vessel atherosclerotic disease confirmed on US, CT or MRI;\n2. stable symptoms and hemodynamics;\n3. age \\>\u002F= 18 years;\n4. given informed consent.\n\nExclusion Criteria:\n\n1. a recent CV event likely to have been embolic in the opinion of the neurologist or cardiologist;\n2. severe LV dysfunction (EF\\\u003C30%);\n3. severe valve disease requiring intervention;\n4. decompensated heart failure;\n5. pregnancy (all women of child bearing potential will have a negative BHCG test;\n6. breastfeeding;\n7. women of childbearing potential who refuse to use two forms of contraception (this includes at least one form of highly effective and one effective method of contraception) throughout the study OR men capable of fathering a child who refuse to use contraception;.\n8. unable to give informed consent;.\n9. Florbetaben allergy;\n10. glomerular filtration rate (GFR) \\\u003C50 ml\u002Fmin\u002F1.72m2\n\nExclusion for CTA portion of the protocol: Patients with dye allergy, or those with GFR \\\u003C60, will not undergo CTA but will have PET\u002FCT.",true,"ALL","18 Years",{"count":72,"type":73},30,"ESTIMATED","OBSERVATIONAL","The Primary Objective is to determine if a new nuclear tracer (named 18F-Florbetaben) used with nuclear imaging (PET imaging) can detect inflamed plaque in patients with recent ACS or stroke\u002FTIA.",[77,78,79,80],"Acute Coronary Syndrome","Stroke","Transient Ischemic Attack","Atherosclerosis of Artery","2026-05-05",{"date":83,"type":84},"2026-05-08","ACTUAL",{"date":86,"type":84},"2023-10-09",{"date":88,"type":73},"2026-08-01",{"name":5,"class":6},1]