[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569882":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":23,"responsibleParty":43,"collaborators":45,"id":110,"slug":111,"hasResults":112,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":112,"sex":118,"minAge":10,"maxAge":10,"enrollmentInfo":119,"targetDuration":10,"studyType":122,"phases":10,"briefSummary":123,"conditions":124,"keywords":126,"overallStatus":25,"whyStopped":10,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":140},{"fullName":5,"class":6},"Queen Mary University of London","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Stent thrombosis group",null,"40 patients who have suffered cardiovascular events attributed to stent thrombosis within one year of post-stent implementation will be recruited.",{"label":13,"type":10,"description":14,"interventionNames":10},"Control group","80 patients not having suffered stent thrombosis but will have uneventful follow-up. An effort will be made so that these patients have similar clinical presentation, baseline demographics and angiographic results post PCI and receive treatment with a similar antiplatelet regime compared to those who suffered stent thrombosis.",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Christos Bourantas","CONTACT","+442073777000","c.bourantas@qmul.ac.uk",{"name":22,"role":18,"phone":10,"phoneExt":10,"email":10},"Andreas Baumbach",[24],{"facility":5,"status":25,"city":26,"state":10,"zip":10,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"RECRUITING","London","United Kingdom","UK",{"type":30,"coordinates":31},"Point",[32,33],-0.12574,51.50853,{"lat":33,"lon":32},[36,37,39,41],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},{"name":17,"role":38,"phone":10,"phoneExt":10,"email":10},"PRINCIPAL_INVESTIGATOR",{"name":22,"role":40,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"name":42,"role":40,"phone":10,"phoneExt":10,"email":10},"Ryo Torri",{"type":44,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[46,49,51,53,55,57,59,61,64,66,68,70,72,74,76,78,80,82,84,86,88,90,92,94,96,98,100,102,104,106,108],{"name":47,"class":48},"Barts Helth NHS Trust","UNKNOWN",{"name":50,"class":6},"Oxford University Hospitals NHS Trust",{"name":52,"class":6},"Royal Free Hospital NHS Foundation Trust",{"name":54,"class":6},"University Hospitals Bristol and Weston NHS Foundation Trust",{"name":56,"class":6},"Mid and South Essex NHS Foundation Trust",{"name":58,"class":6},"Newcastle-upon-Tyne Hospitals NHS Trust",{"name":60,"class":6},"Liverpool Heart and Chest Hospital NHS Foundation Trust",{"name":62,"class":63},"Manchester University NHS Foundation Trust","OTHER_GOV",{"name":65,"class":6},"King's College Hospital NHS Trust",{"name":67,"class":6},"San Giovanni Addolorata Hospital",{"name":69,"class":6},"Medstar Health Research Institute",{"name":71,"class":6},"Medical University of Warsaw",{"name":73,"class":6},"Insel Gruppe AG, University Hospital Bern",{"name":75,"class":6},"Hospital San Carlos, Madrid",{"name":77,"class":6},"The Leeds Teaching Hospitals NHS Trust",{"name":79,"class":48},"McMaster University Health Sciences Centre",{"name":81,"class":6},"Fujita Health University",{"name":83,"class":6},"Harbin Medical University",{"name":85,"class":6},"Yale University",{"name":87,"class":6},"Fundación de Investigación Biomédica - Hospital Universitario de La Princesa",{"name":89,"class":6},"Erasmus Medical Center",{"name":91,"class":48},"Radbound University Medical Center",{"name":93,"class":48},"Department of Cardiovascular Surgery, German Heart Center Munich",{"name":95,"class":6},"Columbia University",{"name":97,"class":6},"The Queen Elizabeth Hospital",{"name":99,"class":48},"Yonsei University Hospital, Seoul, South Korea",{"name":101,"class":6},"Nara Medical University",{"name":103,"class":48},"Shinshu University School of Medicine",{"name":105,"class":63},"University Hospitals Sussex NHS Foundation Trust",{"name":107,"class":48},"Galeazzi Sant'Ambrogio Hospital - Milan",{"name":109,"class":48},"CORRIB Core Lab, University of Galway","100569882","flow-patterns-and-stent-thrombosis-100569882",false,"NCT06700018","Flow Patterns and Stent Thrombosis","Development of a Novel Method for Detailed Evaluation of Blood Flow Patterns in Stented Segments and Assessment of Their Role in Stent Thrombosis","TISIS registry","Inclusion Criteria:\n\n* Patients undergone OCT-guided percutaneous coronary intervention and implanted with a second-generation drug-eluting stent\n* Patients who have suffered thrombosis post-stent implantation\n\nExclusion Criteria:\n\n\\-","ALL",{"count":120,"type":121},120,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to study the effect of haemodynamic forces on thrombus formation and identify haemodynamic markers that predict stent thrombosis events in patients who have undergone OCT-guided percutaneous coronary interventions.\n\nThe primary objective of the study is to examine the efficacy of blood flow patterns in predicting stent thrombosis. Researchers will compare the blood flow patterns of the stent thrombosis group with that of the control group to understand the influence of blood flow patterns on thrombus formation and progression.",[125],"Stent Thrombosis",[127,128,129,130],"stent thrombosis","endothelial shear stress","optical coherence tomography","blood flow simulations","2026-02-26",{"date":133,"type":134},"2026-02-27","ACTUAL",{"date":136,"type":134},"2024-04-01",{"date":138,"type":121},"2026-07-14",{"name":5,"class":6},1]