[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641578":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":26,"responsibleParty":38,"collaborators":26,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":26,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":26,"enrollmentInfo":51,"targetDuration":26,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":67,"whyStopped":26,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":26},{"fullName":5,"class":6},"Cishan Hospital, Ministry of Health and Welfare","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Focused Extracorporeal Shockwave Therapy","EXPERIMENTAL","Participants assigned to this arm will receive second-generation focused extracorporeal shockwave therapy applied to clinically identified tight and painful regions of the upper trapezius and levator scapulae muscles. Treatment will be administered once weekly for 3 consecutive weeks using the Richard Wolf PiezoWave system. Each treatment session will include approximately 3,000 shockwave pulses at a treatment depth of 20 to 25 mm and a frequency of 2 to 4 Hz. The energy level will begin at level 4 and may be gradually increased to a maximum of level 15 according to the participant's clinical response and tolerance.",[13],"Device: Second-Generation Focused Extracorporeal Shockwave Therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Home-Based Neck Exercise Program","ACTIVE_COMPARATOR","Participants assigned to this arm will receive instruction in a standardized home-based neck exercise program for 3 weeks. The program includes cervical flexion, extension, right and left rotation, right and left lateral flexion, and right and left upper cervical rotation performed with the neck in a flexed position. Participants will receive initial instruction and movement correction from a qualified physical therapist, together with written educational materials. Adherence and exercise-related difficulties will be monitored during the study.",[19],"Behavioral: Home-Based Neck Exercise Program",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Second-Generation Focused Extracorporeal Shockwave Therapy","Second-generation focused extracorporeal shockwave therapy will be applied to clinically identified tight and painful regions of the upper trapezius and levator scapulae muscles. Treatment will be administered using the Richard Wolf PiezoWave system once weekly for 3 consecutive weeks. Each session will include approximately 3,000 shockwave pulses at a treatment depth of 20 to 25 mm and a frequency of 2 to 4 Hz. The treatment energy level will begin at level 4 and may be gradually increased to a maximum of level 15 according to the participant's clinical response and tolerance.",[9],null,{"type":28,"name":15,"description":29,"armGroupLabels":30,"otherNames":26},"BEHAVIORAL","Participants will perform a standardized home-based neck exercise program for 3 weeks. The program includes cervical flexion, extension, right and left rotation, right and left lateral flexion, and right and left upper cervical rotation performed with the neck in a flexed position. Each exercise will be performed for 20 repetitions per set, for 3 sets, 5 times per day. Participants will receive initial instruction and movement correction from a qualified physical therapist, together with written educational materials. Adherence and exercise-related difficulties will be monitored during the study.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Chia-Yu Wei, M.S.","CONTACT","+886-7-6613811","5529","ivywei@chis.mohw.gov.tw",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Sheng-Hui Tuan","Attending Physician and Principal Investigator","100641578","focused-shockwave-therapy-for-neck-and-shoulder-myofascial-pain-100641578",false,"NCT07660523","Focused Shockwave Therapy for Neck and Shoulder Myofascial Pain","Effectiveness of Second-Generation Focused Extracorporeal Shockwave Therapy Combined With Ultrasonographic Assessment in Myofascial Pain Syndrome of the Neck and Shoulder: A Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults older than 20 years.\n* Clinical diagnosis of nonspecific neck and shoulder pain primarily arising from muscles and soft tissues in the upper trapezius or levator scapulae region, as determined by a physical medicine and rehabilitation physician.\n* Neck and shoulder pain lasting for at least 3 months.\n* Neck Disability Index score greater than 5.\n* No use of analgesic medication or muscle relaxants within the previous month.\n* No injection therapy, physical therapy, or other treatment for neck and shoulder pain within the previous month.\n* Ability to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Neck or shoulder pain caused by a neurologic disorder, including cervical radiculopathy.\n* Clinical or imaging diagnosis of cervical degenerative joint disease.\n* History of a rheumatic disease, including rheumatoid arthritis or systemic lupus erythematosus.\n* History of head or neck trauma.\n* History of cervical spine surgery.\n* History of whiplash injury.\n* Pregnancy.\n* Current or previous malignancy considered clinically relevant to shockwave therapy.\n* Bleeding disorder.\n* Current use of anticoagulant medication, including warfarin.\n* Acute inflammation or infection at the treatment site.\n* Implanted cardiac pacemaker or implantable cardioverter-defibrillator.\n* Any other condition judged by the study physician to make participation or focused shockwave therapy inappropriate or unsafe.","ALL","20 Years",{"count":52,"type":53},60,"ESTIMATED","INTERVENTIONAL",[56],"NA","Myofascial pain syndrome of the neck and shoulder is a common condition characterized by persistent muscle pain, tenderness, stiffness, and limitations in daily activities. Focused extracorporeal shockwave therapy is a noninvasive treatment that may reduce pain and improve muscle function. However, additional clinical evidence is needed regarding the effectiveness of second-generation focused shockwave therapy and whether ultrasound imaging can objectively detect changes in muscle function after treatment.\n\nThis pilot randomized controlled trial will enroll 60 adults with chronic neck and shoulder myofascial pain syndrome. Participants will be randomly assigned to either a focused shockwave therapy group or a home-based neck exercise group.\n\nParticipants in the focused shockwave therapy group will receive one treatment session per week for three consecutive weeks. Participants in the control group will perform a standardized home exercise program designed to improve neck mobility and reduce muscle tightness.\n\nAssessments will be performed before the intervention, after the intervention, and at follow-up. Study outcomes will include pain intensity measured using the Visual Analogue Scale, neck-related disability measured using the Neck Disability Index, pressure pain threshold measured using an algometer, and upper trapezius muscle thickness and contraction-related changes measured using ultrasound imaging.\n\nThe primary objective is to determine whether focused shockwave therapy is more effective than a home-based neck exercise program in reducing pain and improving neck function. The study will also evaluate whether ultrasound-derived muscle measurements are associated with changes in pain, pressure sensitivity, and functional disability.",[59],"Myofascial Pain Syndrome",[59,9,61,62,63,64,65,66],"Neck and Shoulder Pain","Upper Trapezius Muscle","Pressure Pain Threshold","Ultrasound Imaging","Muscle Thickness","Neck Disability","NOT_YET_RECRUITING","2026-06-19",{"date":70,"type":71},"2026-06-24","ACTUAL",{"date":73,"type":53},"2026-07-13",{"date":75,"type":53},"2027-05-30",{"name":5,"class":6}]