[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100489508":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":26,"responsibleParty":46,"collaborators":10,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":10,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":55,"minAge":56,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":10,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Zhongshan Ophthalmic Center, Sun Yat-sen University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Non-surgical group: Refractive change, ocular parameter changes, and prognosis without surgery",null,"To evaluate the long-term changes in refractive state, ocular parameter, ocular development and visual prognosis in patients without congenital ectopia lentis surgery.",{"label":13,"type":10,"description":14,"interventionNames":10},"Surgical group: Safety and efficacy of different congenital ectopia lentis surgeries","To compare the safety and efficacy of different congenital ectopia lentis surgeries, including phacoemulsification， phacoemulsification + Intraocular lens (IOL) implantation， phacoemulsification + IOL implantation + Capsular Tension Ring implantation or phacoemulsification + IOL implantation + transscleral fixation.",[16],{"name":17,"affiliation":18,"role":19},"Danying Zheng","Guangdong Provincial Clinical Research Center for Ocular Diseases","PRINCIPAL_INVESTIGATOR",[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Dangying Zheng, M.D","CONTACT","020-87330478","zhengdyy@163.com",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Guangdong Provincial Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science","RECRUITING","Guangzhou","Guangdong","510060","China","CN",{"type":36,"coordinates":37},"Point",[38,39],113.25,23.11667,{"lat":39,"lon":38},[42,44],{"name":43,"role":23,"phone":10,"phoneExt":10,"email":10},"Yizhi Liu, PhD",{"name":45,"role":19,"phone":10,"phoneExt":10,"email":10},"Dangying Zheng, MD",{"type":47,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100489508","follow-up-study-on-visual-prognosis-and-complications-of-ectopia-lentis-lens-100489508",false,"NCT05654025","Follow up Study on Visual Prognosis and Complications of Ectopia Lentis Lens","Inclusion Criteria:\n\n* Diagnosed with congenital lens dislocation and age ≥ 3 years old.\n* Agree to participate in this study with written informed consent from patients or legal guardians.\n\nExclusion Criteria:\n\n* History of ophthalmic trauma or other ophthalmic surgeries.\n* Combined with other ophthalmic diseases such as primary glaucoma, uveitis and corneal disease.\n* Patients who could not cooperate in the examinations.",true,"ALL","3 Years",{"count":58,"type":59},604,"ESTIMATED","OBSERVATIONAL","This is a single-centre, observational cohort study with the following objectives: Firstly, the investigators aim to evaluate the vision-related quality of life and mental health status in congenital ectopia lentis patients. Secondly, the investigators target to investigate the correlations between genotype and clinical phenotype in patients of congenital ectopia lentis. Thirdly, to explore the metabolic profiles in the aqueous humor (AH) of patients with congenital ectopia lentis. Lastly, this study aims to explore the longitudinal changes of ocular biological parameters and complications in patients with postoperative congenital ectopia lens in the Chinese population.",[63,64],"Ectopia Lentis","Dislocation, Lens","2024-08-06",{"date":67,"type":68},"2024-08-07","ACTUAL",{"date":70,"type":68},"2022-12-05",{"date":72,"type":59},"2027-12",{"name":5,"class":6},1]