[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100535942":3},{"organization":4,"armGroups":7,"interventions":31,"overallOfficials":10,"centralContacts":37,"locations":43,"responsibleParty":205,"collaborators":209,"id":220,"slug":221,"hasResults":222,"nctId":223,"briefTitle":224,"officialTitle":224,"acronym":10,"eligibilityCriteria":225,"healthyVolunteers":226,"sex":227,"minAge":228,"maxAge":10,"enrollmentInfo":229,"targetDuration":10,"studyType":232,"phases":10,"briefSummary":233,"conditions":234,"keywords":236,"overallStatus":46,"whyStopped":10,"lastUpdateSubmitDate":240,"lastUpdatePostDateStruct":241,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":249},{"fullName":5,"class":6},"Linkoeping University","OTHER_GOV",[8,14,17,20,23,27],{"label":9,"type":10,"description":11,"interventionNames":12},"Male with Fontan circulation",null,"Different data will be collected along with several questionnaires concerning reproductive health. Approximate 100 individuals will be included-",[13],"Other: Questionnaires and functional test",{"label":15,"type":10,"description":11,"interventionNames":16},"Female with Fontan circulation",[13],{"label":18,"type":10,"description":11,"interventionNames":19},"Partner to male with Fontan circulation",[13],{"label":21,"type":10,"description":11,"interventionNames":22},"Partner to female with Fontan circulation",[13],{"label":24,"type":10,"description":25,"interventionNames":26},"Male control group","Different data will be collected along with several questionnaires concerning reproductive health . Approximate 100 individuals will be included",[13],{"label":28,"type":10,"description":29,"interventionNames":30},"Female control group","Different data will be collected along with several questionnaires concerning reproductive health. Approximate 100 individuals will be included",[13],[32],{"type":33,"name":34,"description":35,"armGroupLabels":36,"otherNames":10},"OTHER","Questionnaires and functional test","Data will be collected from different sources. Questinnaires, Medical journal, Obstetrical records and functional tests",[28,15,24,9,21,18],[38],{"name":39,"role":40,"phone":41,"phoneExt":10,"email":42},"Caroline Lilliecreutz, PhD, Docent","CONTACT","+46708731124","caroline.lilliecreutz@regionostergotland.se",[44,61,74,83,95,104,116,124,132,144,156,165,173,185,195],{"facility":45,"status":46,"city":47,"state":48,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Lund University Skåne University Hospital","RECRUITING","Lund","Skåne County","Sweden","SE",{"type":52,"coordinates":53},"Point",[54,55],13.19321,55.70584,{"lat":55,"lon":54},[58],{"name":59,"role":40,"phone":10,"phoneExt":10,"email":60},"Joanna Hlebowicz, Docent PhD","joanna.hlebowicz@med.lu.se",{"facility":62,"status":63,"city":64,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":65,"geoPoint":69,"contacts":70},"Sahlgrenska Academy, University of Gothenburg Sahlgrenska University Hospital","NOT_YET_RECRUITING","Gothenburg",{"type":52,"coordinates":66},[67,68],11.96679,57.70716,{"lat":68,"lon":67},[71],{"name":72,"role":40,"phone":10,"phoneExt":10,"email":73},"Eva Furenäs, MD PhD","eva.furenas@vgregion.se,",{"facility":75,"status":63,"city":64,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":76,"geoPoint":78,"contacts":79},"Sahlgrenska University Hospital,",{"type":52,"coordinates":77},[67,68],{"lat":68,"lon":67},[80],{"name":81,"role":40,"phone":10,"phoneExt":10,"email":82},"Mårten Alkmark, MD PhD","marten.alkmark@vgregion.se",{"facility":84,"status":63,"city":85,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"University Hospital, Linköping","Linköping",{"type":52,"coordinates":87},[88,89],15.62157,58.41086,{"lat":89,"lon":88},[92],{"name":93,"role":40,"phone":10,"phoneExt":10,"email":94},"Alexsandra Trzebiatowska, MD, PhD,","Aleksandra.Trzebiatowska-Krzynska@regionostergotland.se,",{"facility":96,"status":63,"city":47,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":97,"geoPoint":99,"contacts":100},"Skåne University Hospital, Lund University",{"type":52,"coordinates":98},[54,55],{"lat":55,"lon":54},[101],{"name":102,"role":40,"phone":10,"phoneExt":10,"email":103},"Emma von Wowern, MD PhD","emma.von_wowern@med.lu.se",{"facility":105,"status":63,"city":106,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":107,"geoPoint":111,"contacts":112},"Karolinska University Hospital","Stockholm",{"type":52,"coordinates":108},[109,110],18.06871,59.32938,{"lat":110,"lon":109},[113],{"name":114,"role":40,"phone":10,"phoneExt":10,"email":115},"Eva Mattsson, Chief Physician","eva.mattsson@regionstockholm.se,",{"facility":105,"status":63,"city":106,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":117,"geoPoint":119,"contacts":120},{"type":52,"coordinates":118},[109,110],{"lat":110,"lon":109},[121],{"name":122,"role":40,"phone":10,"phoneExt":10,"email":123},"Edit Nagy, MD, PhD","edit.nagy@regionstockholm.se",{"facility":105,"status":63,"city":106,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":125,"geoPoint":127,"contacts":128},{"type":52,"coordinates":126},[109,110],{"lat":110,"lon":109},[129],{"name":130,"role":40,"phone":10,"phoneExt":10,"email":131},"Maria Sennström, MD PhD","maria.sennstrom@ki.se",{"facility":133,"status":63,"city":134,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":135,"geoPoint":139,"contacts":140},"University West, Drottning Silvia's Children's Hospital\u002FSahlgrenska University Hospital,","Trollhättan",{"type":52,"coordinates":136},[137,138],12.28864,58.28365,{"lat":138,"lon":137},[141],{"name":142,"role":40,"phone":10,"phoneExt":10,"email":143},"Malin Berghammer, Professor","malin.berghammer@hv.se",{"facility":145,"status":63,"city":146,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":147,"geoPoint":151,"contacts":152},"Umeå University, Norrland University Hospital","Umeå",{"type":52,"coordinates":148},[149,150],20.25972,63.82842,{"lat":150,"lon":149},[153],{"name":154,"role":40,"phone":10,"phoneExt":10,"email":155},"Bengt Johansson, Professor","bengt.johansson@umu.se",{"facility":157,"status":63,"city":146,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":158,"geoPoint":160,"contacts":161},"Umeå University, Norrlands University Hospital",{"type":52,"coordinates":159},[149,150],{"lat":150,"lon":149},[162],{"name":163,"role":40,"phone":10,"phoneExt":10,"email":164},"Ulrika Ottander, chief physician","ulrika.ottander@umu.se",{"facility":157,"status":63,"city":146,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":166,"geoPoint":168,"contacts":169},{"type":52,"coordinates":167},[149,150],{"lat":150,"lon":149},[170],{"name":171,"role":40,"phone":10,"phoneExt":10,"email":172},"Annika Bay, senior lecturer","Annika.bay@umu.se",{"facility":174,"status":46,"city":175,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":176,"geoPoint":180,"contacts":181},"Akademiska Hospital Uppsala.Uppsala University.","Uppsala",{"type":52,"coordinates":177},[178,179],17.63889,59.85882,{"lat":179,"lon":178},[182],{"name":183,"role":40,"phone":10,"phoneExt":10,"email":184},"Anna-Karin Wikström, Professor","Anna-karin.wikstrom@kbh.uu.se",{"facility":186,"status":46,"city":175,"state":10,"zip":10,"country":49,"countryCode":50,"cosmosGeoPoint":187,"geoPoint":189,"contacts":190},"Uppsala University, Akademiska Hospital",{"type":52,"coordinates":188},[178,179],{"lat":179,"lon":178},[191,193],{"name":192,"role":40,"phone":10,"phoneExt":10,"email":10},"Christina Christersson, Associate Professor",{"name":10,"role":40,"phone":10,"phoneExt":10,"email":194},"christina.christersson@medsci.uu.se",{"facility":196,"status":63,"city":85,"state":197,"zip":198,"country":49,"countryCode":50,"cosmosGeoPoint":199,"geoPoint":201,"contacts":202},"Linköping University, University Hospital","Östergötland County","58158 Linköping",{"type":52,"coordinates":200},[88,89],{"lat":89,"lon":88},[203],{"name":204,"role":40,"phone":41,"phoneExt":10,"email":42},"Caroline Lilliecreutz, PhD Associate professor",{"type":206,"investigatorFullName":207,"investigatorTitle":208,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Caroline Lilliecreutz","MD. PhD, Associate Professor",[210,212,214,216,218],{"name":211,"class":33},"Uppsala University",{"name":213,"class":33},"Umeå University",{"name":215,"class":33},"Lund University",{"name":217,"class":33},"Göteborg University",{"name":219,"class":33},"Karolinska Institutet","100535942","fontan-circulation-and-reproductive-health-in-a-national-swedish-cohort-100535942",false,"NCT06258382","Fontan Circulation and Reproductive Health in a National Swedish Cohort","Inclusion Criteria:\n\n* Fontan circulation,\n* Age ≥18 years at inclusion,\n* Follow-up at specialist clinics,\n* Ability to fill in questionnaires in the Swedish language (no other alternative available) or\n* Partner of a person with Fontan circulation,\n* Age ≥18 years at inclusion\n* Ability to fill in questionnaires in the Swedish language (no other alternative available).\n\nor •Age- and gender-matched individuals are recruited via the population registry. They must not have congenital heart disease.\n\nExclusion criteria: N\u002FA\n\n\\-",true,"ALL","18 Years",{"count":230,"type":231},600,"ESTIMATED","OBSERVATIONAL","In the Swedish registry for congenital heart defects, SWEDCON, over 230 patients with single-ventricle circulation are registered in the adult section.\n\nCongenital heart defects affect career choices, family planning, and leisure activities. Questions regarding heredity and pregnancy are common.\n\nThe impact of Fontan circulation on reproductive health and fertility needs to be illuminated, and additional studies are required from both medical and psychosocial perspectives.Cognitive impairment is common among patients with congenital heart defects but is likely an overlooked cause of long-term illness.\n\nObjective To study a large national population (n=200) of adults with Fontan circulation and their potential partners regarding.\n\n* the prevalence and explanatory factors for sexual dysfunction and infertility in women and men with Fontan circulation (Study A).\n* the outcomes of pregnancy, choice of delivery mode, and complications in patients with Fontan circulation (Study B).\n* the experiences and perceptions of becoming parents among women (n=20) and men (n=20), as well as elucidate reasoning and family planning among women and men (n=20) who have not become parents (Study C).\n* Investigate the prevalence and explanatory factors for (Sub-study D):\n* Fatigue\n* In-depth cognitive screening to describe specific cognitive functions such as auditory memory, visuospatial memory, attention, cognitive speed, and executive functions.\n\nThe aim of this research is to gain more knowledge in an area that has been relatively underexplored, thus improving care for women and men with congenital heart defects.",[235],"Fontan Circulation",[237,238,239],"reproductive health","cognitive impairment","grown up heart disease","2024-10-11",{"date":242,"type":243},"2024-10-16","ACTUAL",{"date":245,"type":243},"2023-11-01",{"date":247,"type":231},"2026-10-01",{"name":207,"class":6},15]