[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635215":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":44,"responsibleParty":62,"collaborators":25,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":25,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":87,"overallStatus":91,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Istanbul Nisantasi University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Foot Reflexology","EXPERIMENTAL","Foot reflexology will be applied in addition to standard care during therapeutic hypothermia. Each session will last approximately 7 minutes (3.5 minutes per foot) and will be performed once daily for three consecutive days by a trained healthcare professional using standardized techniques.",[13],"Other: Foot reflexology",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard Care","ACTIVE_COMPARATOR","Participants will receive standard therapeutic hypothermia and routine neonatal intensive care without any additional tactile stimulation or reflexology.",[19],"Other: Standard care",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Foot reflexology","A standardized foot reflexology protocol will be applied for 7 minutes (3.5 minutes per foot) once daily for three consecutive days during therapeutic hypothermia. The technique includes thumb walking and rotational pressure targeting specific reflex zones. The intervention is administered under controlled thermal conditions to avoid physiological instability.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standard care","Standard therapeutic hypothermia and routine neonatal intensive care without additional tactile stimulation.",[15],[31],{"name":32,"affiliation":33,"role":34},"Alev S Sivaslı, PhD","istanbul nişantaşı üniversitesi","PRINCIPAL_INVESTIGATOR",[36,40],{"name":32,"role":37,"phone":38,"phoneExt":25,"email":39},"CONTACT","+905076661069","aesivasli@gmail.com",{"name":41,"role":37,"phone":42,"phoneExt":25,"email":43},"Ercan S Sivaslı, Professor","+90 5343420027","esivasli@yahoo.com",[45],{"facility":46,"status":25,"city":47,"state":48,"zip":49,"country":50,"countryCode":25,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Nisantasi University","Istanbul","Sarıyer","27590","Turkey (Türkiye)",{"type":52,"coordinates":53},"Point",[54,55],28.94966,41.01384,{"lat":55,"lon":54},[58],{"name":59,"role":37,"phone":60,"phoneExt":25,"email":61},"ercan S sivaslı, PhD","05343420027","alev.sivasli@nisantasi.edu.tr",{"type":34,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Alev Sivasli","Assistant Professor","100635215","foot-reflexology-in-neonates-with-hypoxic-ischemic-encephalopathy-100635215",false,"NCT07549789","Foot Reflexology in Neonates With Hypoxic-Ischemic Encephalopathy","Effect of Foot Reflexology on Comfort and Physiological Parameters in Neonates With Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia: A Randomized Controlled Trial","foot massage","Inclusion Criteria:\n\n* Diagnosed with hypoxic-ischemic encephalopathy\n* Undergoing therapeutic hypothermia\n* Hemodynamically stable neonates\n\nExclusion Criteria:\n\n* Major congenital anomalies\n* Hemodynamic instability\n* Skin integrity problems preventing foot reflexology","ALL","30 Minutes","3 Hours",{"count":77,"type":78},84,"ESTIMATED","INTERVENTIONAL",[81],"NA","This randomized controlled trial aims to evaluate the effect of foot reflexology on comfort levels and physiological parameters in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia. Neonates in the intervention group will receive standardized foot reflexology sessions in addition to routine care, while the control group will receive routine care alone. Comfort will be assessed using the COMFORTneo scale, and physiological parameters will be monitored throughout the intervention period.",[84,85,9,86],"Effect of Reflexology","Hypoxic-Ischemic Encephalopathy, Neonatal","Therapeutic Hypothermia",[22,88,89,90],"therapeutic hypothermia","Hypoxic-Ischemic Encephalopathy","ComfortNeo","NOT_YET_RECRUITING","2026-04-17",{"date":94,"type":95},"2026-04-24","ACTUAL",{"date":97,"type":78},"2026-07",{"date":99,"type":78},"2027-03",{"name":5,"class":6},1]