[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100595554":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":29,"locations":24,"responsibleParty":35,"collaborators":24,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":24,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":47,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":24,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":24,"overallStatus":59,"whyStopped":24,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":24},{"fullName":5,"class":6},"Assiut University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Fractional Co2 laser","EXPERIMENTAL","Combination Product:\" Fractional CO2 laser\" and \"topical fluconazole microemulsion\"",[13],"Combination Product: \"Fractional CO2 laser\" and \"topical fluconazole microemulsion\"",{"label":15,"type":10,"description":16,"interventionNames":17},"Urea 40%","Combination Product: \"Urea 40%\" and \"topical fluconazole microemulsion\"",[16],[19,25],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"COMBINATION_PRODUCT","\"Fractional CO2 laser\" and \"topical fluconazole microemulsion\"","four sessions of fractional CO2 at 3weeks interval with a laser device (multixel, Daeshin enterprise co., LTD. (D.S.E) 105, 271, digital -ro, Guro-gu, Seoul, Koreaa) at a pulse energy of 140 mJ, a density of 150 spots\u002F cm2 and a depth of 1 cm combined with twice daily topical fluconazole microemulsion.",[9],null,{"type":20,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"\"Urea 40%\" and \"topical fluconazole microemulsion\"","urea 40% paste under occlusion once daily over 4 weeks followed by topical fluconazole microemulsion twice daily for 8 weeks.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Shaza alaa abdelmoneim","CONTACT","+201122882280","sherialaa9@gmail.com",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Shaza Alaa Ezzat Abdel-moneim","doctor","100595554","fractional-co-laser-or-40-urea-with-topical-fluconazole-microemulsion-in-onychomycosis-100595554",false,"NCT07033962","Fractional CO₂ Laser or 40% Urea With Topical Fluconazole Microemulsion in Onychomycosis","Comparative Study Between Fractional CO₂ Laser and 40% Urea Assisted Delivery of Topical Fluconazole Microemulsion in the Treatment of Onychomycosis","Inclusion Criteria:\n\n* Clinically and mycologically confirmed onychomycosis\n* No topical antifungal use in the past 1 month\n* No systemic antifungal use in the past 3 months\n\nExclusion Criteria:\n\n* pregnancy or lactation\n* Nail disorders such as psoriasis, eczema, lichen planus\n* patients have a known allergy to any of the study treatments",true,"ALL","18 Years","65 Years",{"count":51,"type":52},40,"ESTIMATED","INTERVENTIONAL",[55],"NA","To evaluate the efficacy and safety of topical fluconazole microemulsion enhanced by fractional CO₂ laser versus by 40% urea ablation in treatment of Onychomycosis.",[58],"Onychomycosis","NOT_YET_RECRUITING","2025-06-25",{"date":62,"type":63},"2025-06-29","ACTUAL",{"date":65,"type":52},"2025-06",{"date":67,"type":52},"2026-07",{"name":5,"class":6}]