[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574296":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":15,"collaborators":10,"id":19,"slug":20,"hasResults":21,"nctId":22,"briefTitle":23,"officialTitle":24,"acronym":10,"eligibilityCriteria":25,"healthyVolunteers":21,"sex":26,"minAge":27,"maxAge":10,"enrollmentInfo":28,"targetDuration":31,"studyType":32,"phases":10,"briefSummary":33,"conditions":34,"keywords":10,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":10},{"fullName":5,"class":6},"Selcuk University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Frail",null,"CFS Level ≥4",{"label":13,"type":10,"description":14,"interventionNames":10},"Non-frail","CFS Level ≤3",{"type":16,"investigatorFullName":17,"investigatorTitle":18,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Mehmet SARGIN","Associate Professor","100574296","frailty-and-spinal-anesthesia-induced-hypotension-in-elderly-100574296",false,"NCT06757439","Frailty and Spinal Anesthesia-Induced Hypotension in Elderly","Effect of Frailty on Spinal Anesthesia-induced Hypotension in Geriatric Patients","Inclusion Criteria:\n\n* 65 and older\n* ASA I-III physical status\n* Undergoing elective surgery under spinal anesthesia\n\nExclusion Criteria:\n\n* Patients with cardiac arrhythmia\n* Patients with severe heart failure\n* Patients with cerebrovascular disease\n* Contraindications to neuraxial anesthesia","ALL","65 Years",{"count":29,"type":30},60,"ESTIMATED","1 Day","OBSERVATIONAL","60 patients aged 65 and older with ASA I-III physical status undergoing elective surgery under spinal anesthesia will be included in the study.\n\nPatients with cardiac arrhythmia, severe heart failure, cerebrovascular disease, or contraindications to neuraxial anesthesia will be excluded. Frailty assessments will be performed using the Clinical Frailty Scale (CFS) version 2.0 by anesthesiologists in preoperative clinics or wards. Participants will be categorized into frail (CFS Level ≥4, Group I) and non-frail (CFS Level ≤3, Group II) groups.\n\nPrior to spinal anesthesia, 8 mL\u002Fkg of crystalloids will be administered. Baseline preoperative mean arterial blood pressure (MABP) and heart rate (HR) will be recorded as the average of three measurements in the supine position.\n\nDuring the study, MABP and HR will be monitored every 2 minutes for the first 20 minutes post-spinal anesthesia, then every 5 minutes until surgery ends. Hypotension (MABP \\\u003C80% of baseline) will be treated with 5 mg intravenous ephedrine, while bradycardia (HR \\\u003C50 beats\u002Fmin) will be treated with 0.5 mg intravenous atropine.",[35,36],"Frailty","Spinal Anesthesia","NOT_YET_RECRUITING","2025-01-02",{"date":40,"type":41},"2025-01-03","ACTUAL",{"date":43,"type":30},"2025-01-20",{"date":45,"type":30},"2025-03-20",{"name":5,"class":6}]