[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499384":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":53,"collaborators":10,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":70,"studyType":71,"phases":10,"briefSummary":72,"conditions":73,"keywords":80,"overallStatus":32,"whyStopped":10,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University Hospital Freiburg","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients allocated to implantation of a transjugular intrahepatic portosystemic shunt (TIPS)",null,"Patients allocated to implantation of a transjugular intrahepatic portosystemic shunt (TIPS) due to cirrhotic and non-cirrhotic portal hypertension",[13],"Device: Implantation of a transjugular intrahepatic portosystemic shunt (TIPS)",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","Implantation of a transjugular intrahepatic portosystemic shunt (TIPS)","For TIPS implantation, a transjugular approach is used in all patients and a puncture needle was advanced into a hepatic vein. Puncture of the portal vein is performed using ultrasound guidance followed by portography after successful puncture of the portal vein. Further, the parenchymal tract isdilated and the stent graft is placed. Before and after TIPS implantation, portal venous and central venous pressures are measured to calculate the porto-systemic pressure gradient",[9],[21],{"name":22,"affiliation":5,"role":23},"Dominik Bettinger, MD","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},"CONTACT","49761270-36870","dominik.bettinger@uniklinik-freiburg.de",[30],{"facility":31,"status":32,"city":33,"state":10,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"University Medical Center Freiburg, Department of Medicine II","RECRUITING","Freiburg im Breisgau","79106","Germany","DE",{"type":38,"coordinates":39},"Point",[40,41],7.85222,47.9959,{"lat":41,"lon":40},[44,45,46,49,51],{"name":22,"role":26,"phone":27,"phoneExt":10,"email":28},{"name":22,"role":23,"phone":10,"phoneExt":10,"email":10},{"name":47,"role":48,"phone":10,"phoneExt":10,"email":10},"Michael Schultheiß, MD","SUB_INVESTIGATOR",{"name":50,"role":48,"phone":10,"phoneExt":10,"email":10},"Lukas Sturm, MD",{"name":52,"role":48,"phone":10,"phoneExt":10,"email":10},"Marlene Reincke, MD",{"type":23,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Prof. Dr. Dominik Bettinger","MD","100499384","freiburg-tips-registry-100499384",false,"NCT05782556","Freiburg TIPS Registry","Transjugular Intrahepatic Portosystemic Shunt (TIPS) for the Treatment of Portal Hypertension: an Observational Study","FRETIR","Inclusion Criteria:\n\n* Patients allocated to TIPS implantation due to clinically significant cirrhotic and non-cirrhotic portal hypertension\n\nExclusion Criteria:\n\n* Withdrawal of written informed consent","ALL","18 Years","100 Years",{"count":68,"type":69},2000,"ESTIMATED","12 Months","OBSERVATIONAL","Patients with clinically significant portal hypertension allocated to implantation of a transjugular intrahepatic portosystemic shunt (TIPS) at the Department of Medicine II of the University Medical Center Freiburg, Germany will be offered to participate in this prospective observational trial.\n\nClinical and laboratory as well as outcome parameters will be assessed before and within the first 12 months after TIPS implantation following a regular follow-up schedule with clinical visits at the University Medical Center Freiburg. During follow-up visits, serum\u002Fplasma samples and peripheral blood mononuclear cells (PBMC) are collected and stored in a associated biobank.",[74,75,76,77,78,79],"Liver Cirrhosis","Portal Hypertension","Non-Cirrhotic Portal Hypertension","Budd Chiari Syndrome","Portal Vein Thrombosis","Portal Systemic Shunt",[81,82,76,83,84],"Liver cirhosis","Transjugular intrahepatic portosystemic shunt","Prognosis","Outcome","2026-04-27",{"date":87,"type":88},"2026-05-01","ACTUAL",{"date":90,"type":88},"2023-01-01",{"date":92,"type":69},"2034-06-30",{"name":5,"class":6},1]