[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567378":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":11,"centralContacts":15,"locations":23,"responsibleParty":461,"collaborators":10,"id":463,"slug":464,"hasResults":465,"nctId":466,"briefTitle":467,"officialTitle":468,"acronym":10,"eligibilityCriteria":469,"healthyVolunteers":465,"sex":470,"minAge":471,"maxAge":472,"enrollmentInfo":473,"targetDuration":10,"studyType":476,"phases":10,"briefSummary":477,"conditions":478,"keywords":10,"overallStatus":139,"whyStopped":10,"lastUpdateSubmitDate":480,"lastUpdatePostDateStruct":481,"startDateStruct":484,"completionDateStruct":486,"leadSponsor":488,"locationsCount":489},{"fullName":5,"class":6},"Hoffmann-La Roche","INDUSTRY",[8],{"label":9,"type":10,"description":10,"interventionNames":10},"Participants Who Are Huntington Disease Gene Expansion Carriers",null,[12],{"name":13,"affiliation":5,"role":14},"Clinical Trials","STUDY_DIRECTOR",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Reference Study ID Number: WE45491 https:\u002F\u002Fforpatients.roche.com\u002F No attachments to email below.","CONTACT","888-662-6728 (U.S. Only)","global-roche-genentech-trials@gene.com",{"name":22,"role":18,"phone":10,"phoneExt":10,"email":10},"Fastest response: use the inquiry form. https:\u002F\u002Fwww.gene.com\u002Fcontact-us\u002Fsubmit-medical-inquiry",[24,38,48,58,67,77,87,97,107,117,127,137,148,158,164,171,180,190,200,212,222,232,242,252,263,274,283,292,301,313,323,333,342,351,357,366,377,386,397,406,415,424,434,443,452],{"facility":25,"status":26,"city":27,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":10},"Uab Medicine","COMPLETED","Birmingham","Alabama","35294","United States","US",{"type":33,"coordinates":34},"Point",[35,36],-86.80249,33.52066,{"lat":36,"lon":35},{"facility":39,"status":26,"city":40,"state":41,"zip":42,"country":30,"countryCode":31,"cosmosGeoPoint":43,"geoPoint":47,"contacts":10},"Barrow Neurological Institute","Phoenix","Arizona","85013",{"type":33,"coordinates":44},[45,46],-112.07404,33.44838,{"lat":46,"lon":45},{"facility":49,"status":26,"city":50,"state":51,"zip":52,"country":30,"countryCode":31,"cosmosGeoPoint":53,"geoPoint":57,"contacts":10},"University of California San Diego","La Jolla","California","92037-1337",{"type":33,"coordinates":54},[55,56],-117.2742,32.84727,{"lat":56,"lon":55},{"facility":59,"status":26,"city":60,"state":51,"zip":61,"country":30,"countryCode":31,"cosmosGeoPoint":62,"geoPoint":66,"contacts":10},"University of California Davis Medical System","Sacramento","95817",{"type":33,"coordinates":63},[64,65],-121.4944,38.58157,{"lat":65,"lon":64},{"facility":68,"status":26,"city":69,"state":70,"zip":71,"country":30,"countryCode":31,"cosmosGeoPoint":72,"geoPoint":76,"contacts":10},"CenExel Rocky Mountain Clinical Research, LLC","Englewood","Colorado","80113",{"type":33,"coordinates":73},[74,75],-104.98776,39.64777,{"lat":75,"lon":74},{"facility":78,"status":26,"city":79,"state":80,"zip":81,"country":30,"countryCode":31,"cosmosGeoPoint":82,"geoPoint":86,"contacts":10},"University of South Florida","Tampa","Florida","33612",{"type":33,"coordinates":83},[84,85],-82.45843,27.94752,{"lat":85,"lon":84},{"facility":88,"status":26,"city":89,"state":90,"zip":91,"country":30,"countryCode":31,"cosmosGeoPoint":92,"geoPoint":96,"contacts":10},"Northwestern University","Chicago","Illinois","60611",{"type":33,"coordinates":93},[94,95],-87.65005,41.85003,{"lat":95,"lon":94},{"facility":98,"status":26,"city":99,"state":100,"zip":101,"country":30,"countryCode":31,"cosmosGeoPoint":102,"geoPoint":106,"contacts":10},"University of Iowa Hospitals and Clinics","Iowa City","Iowa","52242",{"type":33,"coordinates":103},[104,105],-91.53017,41.66113,{"lat":105,"lon":104},{"facility":108,"status":26,"city":109,"state":110,"zip":111,"country":30,"countryCode":31,"cosmosGeoPoint":112,"geoPoint":116,"contacts":10},"John Hopkins University School of Medicine","Baltimore","Maryland","21287",{"type":33,"coordinates":113},[114,115],-76.61219,39.29038,{"lat":115,"lon":114},{"facility":118,"status":26,"city":119,"state":120,"zip":121,"country":30,"countryCode":31,"cosmosGeoPoint":122,"geoPoint":126,"contacts":10},"Beth Israel Deaconess Medical Center","Boston","Massachusetts","02215",{"type":33,"coordinates":123},[124,125],-71.05977,42.35843,{"lat":125,"lon":124},{"facility":128,"status":26,"city":129,"state":130,"zip":131,"country":30,"countryCode":31,"cosmosGeoPoint":132,"geoPoint":136,"contacts":10},"University of Pittsburgh","Pittsburgh","Pennsylvania","15213",{"type":33,"coordinates":133},[134,135],-79.99589,40.44062,{"lat":135,"lon":134},{"facility":138,"status":139,"city":140,"state":141,"zip":142,"country":30,"countryCode":31,"cosmosGeoPoint":143,"geoPoint":147,"contacts":10},"Vanderbilt University Medical Center","RECRUITING","Nashville","Tennessee","37212",{"type":33,"coordinates":144},[145,146],-86.78444,36.16589,{"lat":146,"lon":145},{"facility":149,"status":26,"city":150,"state":151,"zip":152,"country":30,"countryCode":31,"cosmosGeoPoint":153,"geoPoint":157,"contacts":10},"EvergreenHealth Investigational Drug Services","Kirkland","Washington","98034",{"type":33,"coordinates":154},[155,156],-122.20874,47.68149,{"lat":156,"lon":155},{"facility":159,"status":26,"city":160,"state":10,"zip":161,"country":162,"countryCode":163,"cosmosGeoPoint":10,"geoPoint":10,"contacts":10},"Hospital Britanico de Buenos Aires","Ciudad Autonoma Buenos Aires","C1284AEB","Argentina","AR",{"facility":165,"status":139,"city":166,"state":167,"zip":168,"country":169,"countryCode":170,"cosmosGeoPoint":10,"geoPoint":10,"contacts":10},"Calvary Health Care Bethlehem","Caulfield South","New South Wales","3162","Australia","AU",{"facility":172,"status":139,"city":173,"state":167,"zip":174,"country":169,"countryCode":170,"cosmosGeoPoint":175,"geoPoint":179,"contacts":10},"Westmead Hospital","Westmead","2145",{"type":33,"coordinates":176},[177,178],150.98768,-33.80383,{"lat":178,"lon":177},{"facility":181,"status":139,"city":182,"state":183,"zip":184,"country":169,"countryCode":170,"cosmosGeoPoint":185,"geoPoint":189,"contacts":10},"Royal Melbourne Hospital","Parkville","Victoria","3050",{"type":33,"coordinates":186},[187,188],144.95,-37.78333,{"lat":188,"lon":187},{"facility":191,"status":139,"city":192,"state":193,"zip":194,"country":169,"countryCode":170,"cosmosGeoPoint":195,"geoPoint":199,"contacts":10},"Graylands Hospital","Mount Claremont","Western Australia","6010",{"type":33,"coordinates":196},[197,198],115.78337,-31.96177,{"lat":198,"lon":197},{"facility":201,"status":139,"city":202,"state":203,"zip":204,"country":205,"countryCode":206,"cosmosGeoPoint":207,"geoPoint":211,"contacts":10},"University of Alberta","Edmonton","Alberta","T6G 2G3","Canada","CA",{"type":33,"coordinates":208},[209,210],-113.46871,53.55014,{"lat":210,"lon":209},{"facility":213,"status":139,"city":214,"state":215,"zip":216,"country":205,"countryCode":206,"cosmosGeoPoint":217,"geoPoint":221,"contacts":10},"University of British Columbia Hospital","Vancouver","British Columbia","V6T 2B5",{"type":33,"coordinates":218},[219,220],-123.11934,49.24966,{"lat":220,"lon":219},{"facility":223,"status":139,"city":224,"state":225,"zip":226,"country":205,"countryCode":206,"cosmosGeoPoint":227,"geoPoint":231,"contacts":10},"Centricity Research","Halifax","Nova Scotia","B3S 1N2",{"type":33,"coordinates":228},[229,230],-63.57688,44.64269,{"lat":230,"lon":229},{"facility":233,"status":139,"city":234,"state":235,"zip":236,"country":205,"countryCode":206,"cosmosGeoPoint":237,"geoPoint":241,"contacts":10},"North York General Hospital","Toronto","Ontario","M2J 1V1",{"type":33,"coordinates":238},[239,240],-79.39864,43.70643,{"lat":240,"lon":239},{"facility":243,"status":139,"city":244,"state":245,"zip":246,"country":205,"countryCode":206,"cosmosGeoPoint":247,"geoPoint":251,"contacts":10},"McGill University","Montreal","Quebec","H3A 2B4",{"type":33,"coordinates":248},[249,250],-73.58781,45.50884,{"lat":250,"lon":249},{"facility":253,"status":139,"city":254,"state":10,"zip":255,"country":256,"countryCode":257,"cosmosGeoPoint":258,"geoPoint":262,"contacts":10},"Rigshospitalet, Hukommelsesklinikken","København Ø","2100","Denmark","DK",{"type":33,"coordinates":259},[260,261],12.56862,55.70968,{"lat":261,"lon":260},{"facility":264,"status":139,"city":265,"state":10,"zip":266,"country":267,"countryCode":268,"cosmosGeoPoint":269,"geoPoint":273,"contacts":10},"Charité - Universitätsmed. Berlin, Klinik für Psychiatrie und Psychotherapie","Berlin","10117","Germany","DE",{"type":33,"coordinates":270},[271,272],13.41053,52.52437,{"lat":272,"lon":271},{"facility":275,"status":26,"city":276,"state":10,"zip":277,"country":267,"countryCode":268,"cosmosGeoPoint":278,"geoPoint":282,"contacts":10},"St. Josef-Hospital, Neurologische Klinik der Ruhr-Uni","Bochum","44791",{"type":33,"coordinates":279},[280,281],7.21648,51.48165,{"lat":281,"lon":280},{"facility":284,"status":139,"city":285,"state":10,"zip":286,"country":267,"countryCode":268,"cosmosGeoPoint":287,"geoPoint":291,"contacts":10},"Universitätsklinikum Erlangen, Abteilung Molekulare Neurologie","Erlangen","91054",{"type":33,"coordinates":288},[289,290],11.00783,49.59099,{"lat":290,"lon":289},{"facility":293,"status":139,"city":294,"state":10,"zip":295,"country":267,"countryCode":268,"cosmosGeoPoint":296,"geoPoint":300,"contacts":10},"Universitätsklinikum Ulm","Ulm","89081",{"type":33,"coordinates":297},[298,299],9.99155,48.39841,{"lat":299,"lon":298},{"facility":302,"status":139,"city":303,"state":304,"zip":305,"country":306,"countryCode":307,"cosmosGeoPoint":308,"geoPoint":312,"contacts":10},"Fondazione IRCCS Istituto Neurologico Carlo Besta","Milan","Lombardy","20133","Italy","IT",{"type":33,"coordinates":309},[310,311],9.18951,45.46427,{"lat":311,"lon":310},{"facility":314,"status":139,"city":315,"state":316,"zip":317,"country":306,"countryCode":307,"cosmosGeoPoint":318,"geoPoint":322,"contacts":10},"Universita Degli Studi Di Firenze","Florence","Tuscany","50134",{"type":33,"coordinates":319},[320,321],11.24626,43.77925,{"lat":321,"lon":320},{"facility":324,"status":139,"city":325,"state":10,"zip":10,"country":326,"countryCode":327,"cosmosGeoPoint":328,"geoPoint":332,"contacts":10},"Auckland DHB - Neurlogy Department","Auckland","New Zealand","NZ",{"type":33,"coordinates":329},[330,331],174.76349,-36.84853,{"lat":331,"lon":330},{"facility":334,"status":26,"city":335,"state":10,"zip":336,"country":326,"countryCode":327,"cosmosGeoPoint":337,"geoPoint":341,"contacts":10},"New Zealand Brain Research Institute","Christchurch","8011",{"type":33,"coordinates":338},[339,340],172.63333,-43.53333,{"lat":340,"lon":339},{"facility":343,"status":139,"city":344,"state":10,"zip":345,"country":326,"countryCode":327,"cosmosGeoPoint":346,"geoPoint":350,"contacts":10},"Wellington Hospital","Wellington","6021",{"type":33,"coordinates":347},[348,349],174.77557,-41.28664,{"lat":349,"lon":348},{"facility":352,"status":139,"city":353,"state":10,"zip":354,"country":355,"countryCode":356,"cosmosGeoPoint":10,"geoPoint":10,"contacts":10},"Szpital Sw. Wojciecha","Gda?sk","80-462","Poland","PL",{"facility":358,"status":139,"city":359,"state":10,"zip":360,"country":355,"countryCode":356,"cosmosGeoPoint":361,"geoPoint":365,"contacts":10},"Wojskowy Instytut Medycyny Lotniczej","Warsaw","01-755",{"type":33,"coordinates":362},[363,364],21.01178,52.22977,{"lat":364,"lon":363},{"facility":367,"status":139,"city":368,"state":10,"zip":369,"country":370,"countryCode":371,"cosmosGeoPoint":372,"geoPoint":376,"contacts":10},"Unidade Local de Saude de Santa Maria, E.P.E. - Hospital de Santa Maria","Lisbon","1649-035","Portugal","PT",{"type":33,"coordinates":373},[374,375],-9.1498,38.72509,{"lat":375,"lon":374},{"facility":378,"status":26,"city":379,"state":10,"zip":380,"country":370,"countryCode":371,"cosmosGeoPoint":381,"geoPoint":385,"contacts":10},"CNS - Campus Neurológico","Torres Vedras","2560-280",{"type":33,"coordinates":382},[383,384],-9.2586,39.09109,{"lat":384,"lon":383},{"facility":387,"status":139,"city":388,"state":10,"zip":389,"country":390,"countryCode":391,"cosmosGeoPoint":392,"geoPoint":396,"contacts":10},"Hospital Universitario de Badajoz","Badajoz","06080","Spain","ES",{"type":33,"coordinates":393},[394,395],-6.97061,38.87789,{"lat":395,"lon":394},{"facility":398,"status":139,"city":399,"state":10,"zip":400,"country":390,"countryCode":391,"cosmosGeoPoint":401,"geoPoint":405,"contacts":10},"Hospital de la Santa Creu i Sant Pau","Barcelona","08041",{"type":33,"coordinates":402},[403,404],2.15899,41.38879,{"lat":404,"lon":403},{"facility":407,"status":139,"city":408,"state":10,"zip":409,"country":390,"countryCode":391,"cosmosGeoPoint":410,"geoPoint":414,"contacts":10},"Hospital Universitario de Burgos. Servicio de Neurología","Burgos","09006",{"type":33,"coordinates":411},[412,413],-3.70184,42.34106,{"lat":413,"lon":412},{"facility":416,"status":139,"city":417,"state":10,"zip":418,"country":390,"countryCode":391,"cosmosGeoPoint":419,"geoPoint":423,"contacts":10},"Hospital Ramon y Cajal","Madrid","28034",{"type":33,"coordinates":420},[421,422],-3.70256,40.4165,{"lat":422,"lon":421},{"facility":425,"status":139,"city":27,"state":10,"zip":426,"country":427,"countryCode":428,"cosmosGeoPoint":429,"geoPoint":433,"contacts":10},"Birmingham and Solihull Mental Health Foundation NHS Trust","B16 8PF","United Kingdom","UK",{"type":33,"coordinates":430},[431,432],-1.89983,52.48142,{"lat":432,"lon":431},{"facility":435,"status":139,"city":436,"state":10,"zip":437,"country":427,"countryCode":428,"cosmosGeoPoint":438,"geoPoint":442,"contacts":10},"Addenbrookes Hospital","Cambridge","CB2 0QQ",{"type":33,"coordinates":439},[440,441],0.11667,52.2,{"lat":441,"lon":440},{"facility":444,"status":139,"city":445,"state":10,"zip":446,"country":427,"countryCode":428,"cosmosGeoPoint":447,"geoPoint":451,"contacts":10},"National Hospital For Neurology and Neurosurgery","London","WC1N 3BG",{"type":33,"coordinates":448},[449,450],-0.12574,51.50853,{"lat":450,"lon":449},{"facility":453,"status":139,"city":454,"state":10,"zip":455,"country":427,"countryCode":428,"cosmosGeoPoint":456,"geoPoint":460,"contacts":10},"John Radcliffe Hospital","Oxford","OX3 9DU",{"type":33,"coordinates":457},[458,459],-1.25596,51.75222,{"lat":459,"lon":458},{"type":462,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100567378","frequency-of-selected-single-nucleotide-polymorphisms-in-huntington-disease-gene-expansion-carriers-100567378",false,"NCT06667414","Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers","Frequency of Selected Single Nucleotide Polymorphisms in Phase With the Mutant and Wild-Type HTT Alleles in Huntington Disease Gene Expansion Carriers","Inclusion Criteria:\n\n* Have signed the Informed Consent Form (ICF)\n* Aged 25 to 60 years, inclusive, at the time of signing the ICF\n* Confirmation of Huntington Disease (HD) gene expansion mutation carrier status\n* Confirmation of Total Functional Capacity (TFC) ≥9 and Total Motor Score (TMS) \\>6 within 12 months prior to signing the ICF\n* Ability to tolerate blood draws\n\nExclusion Criteria:\n\n* None","ALL","25 Years","60 Years",{"count":474,"type":475},600,"ESTIMATED","OBSERVATIONAL","For participation in this epidemiological study, a single-day visit at the study site is required. Participants will be recruited from Huntington Disease clinics, and they will be asked to answer questions regarding their demographics, including sex, age, race and ethnicity, and their medical and medication history. At the end of the visit, a blood sample will be drawn to allow testing with a sequencing assay that is specifically designed for phasing single nucleotide polymorphisms (SNPs) on the wild-type Huntington (wtHTT) and mutant Huntington (mHTT) alleles.",[479],"Huntington Disease","2026-06-26",{"date":482,"type":483},"2026-06-29","ACTUAL",{"date":485,"type":483},"2024-09-02",{"date":487,"type":475},"2027-02-28",{"name":5,"class":6},45]