[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574045":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":65,"collaborators":67,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":77,"eligibilityCriteria":78,"healthyVolunteers":73,"sex":79,"minAge":80,"maxAge":24,"enrollmentInfo":81,"targetDuration":24,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Alcohol Non-Avoidance Case-Crossover Arm","EXPERIMENTAL","On a given day of the 14-day study period, participants may be randomly assigned to not avoid consuming alcohol. All participants will be instructed that any alcohol consumed should not be more than 2 drinks in a 24 hour period for men and not more than 1 drink in a 24 hour period for women.\n\nThe frequency of randomization will be tailored to the baseline usual frequency of alcohol consumption: For example, those who drink an average of 4 days a week\u002Fdon't drink 3 days a week will have their randomization programmed to assure an average of 7 non-drinking days over the two-week period. Participants will not receive the same randomization assignment more than two consecutive days in a row.\n\nParticipants will press a button on their continuously recording ECG monitor to time-stamp every alcohol drink consumed.",[13],"Behavioral: Alcohol Consumption Randomized Instructions",{"label":15,"type":10,"description":16,"interventionNames":17},"Alcohol Avoidance Case-Crossover Arm","On a given day of the 14-day study period, participants may be randomly assigned to avoid consuming alcohol.\n\nThe frequency of randomization will be tailored to the baseline usual frequency of alcohol consumption: For example, those who drink an average of 4 days a week\u002Fdon't drink 3 days a week will have their randomization programmed to assure an average of 7 non-drinking days over the two-week period. Participants will not receive the same randomization assignment more than two consecutive days in a row.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","Alcohol Consumption Randomized Instructions","Alcohol Avoidance: In this intervention assignment, participants will be instructed to avoid drinking alcohol for this day.\n\nAlcohol Non-Avoidance: In this intervention assignment, participants will be allowed to drink alcohol for this day.",[15,9],null,[26],{"name":27,"affiliation":5,"role":28},"Gregory Marcus, MD, MAS","PRINCIPAL_INVESTIGATOR",[30,35],{"name":31,"role":32,"phone":33,"phoneExt":24,"email":34},"Gregory M Marcus, MD, MAS","CONTACT","415-476-5706","greg.marcus@ucsf.edu",{"name":36,"role":32,"phone":37,"phoneExt":24,"email":38},"Hannah H Oo, BS","415-476-4999","hannah.oo@ucsf.edu",[40,57],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"UCSF Medical Center at Parnassus","RECRUITING","San Francisco","California","94143","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-122.41942,37.77493,{"lat":52,"lon":51},[55],{"name":56,"role":32,"phone":33,"phoneExt":24,"email":34},"Study Principal Investigator",{"facility":58,"status":42,"city":43,"state":44,"zip":59,"country":46,"countryCode":47,"cosmosGeoPoint":60,"geoPoint":62,"contacts":63},"UCSF Medical Center at Mission Bay","94158",{"type":49,"coordinates":61},[51,52],{"lat":52,"lon":51},[64],{"name":56,"role":32,"phone":33,"phoneExt":24,"email":34},{"type":66,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[68],{"name":69,"class":70},"National Institute on Alcohol Abuse and Alcoholism (NIAAA)","NIH","100574045","full-avoidance-vs-permissiveregulated-drinking--outcomes-on-fibrillation-100574045",false,"NCT06754176","Full-Avoidance vs. Permissive\u002FRegulated Drinking & Outcomes On Fibrillation","Full-Avoidance vs. Permissive\u002FRegulated Drinking & Outcomes On Fibrillation (FULL-PROOF)","FULL-PROOF","Inclusion Criteria\n\n* Comfortable reading and writing in English\n* Have a smartphone and willing and able to use the Eureka mobile application\n* Currently diagnosed with paroxysmal AFib without a plan to change their AFib management during the two-week monitoring period\n* At least one episode of AFib in the past month OR, in the judgement of a healthcare provider, could potentially have one episode of AF in the next month\n* Drank alcohol at least 1 day\u002Fweek on average in the past month\n* Willing and able to be randomly assigned daily to avoid or not avoid drinking alcohol over a 2-week period\n* Willing and able to provide written informed consent\n\nExclusion Criteria\n\n* Only post-operative AFib\n* Greater than 40% ventricular pacing\n* History of alcohol addiction or abuse determined by self-reported history or AUDIT-C score\n* Intolerance to alcohol\n* History of liver disease\n* Currently incarcerated\n* Currently pregnant or trying to get pregnant","ALL","21 Years",{"count":82,"type":83},100,"ESTIMATED","INTERVENTIONAL",[86],"NA","The goal of this study is to assess the short-term effects of minimal and moderate drinking on atrial fibrillation (AFib) episodes in a real-world population diagnosed with 'come-and-go'\u002Fparoxysmal AFib. The question it aims to answer is:\n\nIs there a greater occurrence of AFib episodes when participants are allowed to consume alcohol according to random assignment?\n\nParticipants will:\n\n* Be given daily random assignments to avoid or not to avoid alcohol\n* Wear an adhesive electrocardiographic (ECG) heart monitor\n* Wear a wrist-worn fitness tracker\n* Wear an anklet transdermal alcohol monitor\n* Wear an adhesive glucose monitor\n* Complete morning and evening surveys daily\n\nParticipants may be compensated up to $50 for full completion of the study. This study can be done in-person or remote.",[89,90],"Atrial Fibrillation (AF)","Atrial Fibrillation (Paroxysmal)",[92,93,94,95,96,97,98],"Alcohol","Drinking","Mediterranean Drinking Pattern","Atrial Fibrillation","AFib","AF","Heart Rhythm","2025-12-19",{"date":101,"type":102},"2025-12-23","ACTUAL",{"date":104,"type":102},"2025-04-17",{"date":106,"type":83},"2029-08",{"name":5,"class":6},2]