[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624908":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":53,"collaborators":26,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":26,"eligibilityCriteria":62,"healthyVolunteers":59,"sex":63,"minAge":64,"maxAge":26,"enrollmentInfo":65,"targetDuration":26,"studyType":68,"phases":69,"briefSummary":71,"conditions":72,"keywords":74,"overallStatus":78,"whyStopped":26,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Universidade do Estado do Pará","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"TMI Group (GT)","ACTIVE_COMPARATOR","Participants in this arm will undergo an intervention consisting of resistance and aerobic exercises, combined with inspiratory muscle training. The protocol will be conducted over 7 weeks, comprising 20 sessions performed 3 times per week.",[13],"Device: Pulmonary rehabilitation combined with inspiratory muscle training",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group (CG)","SHAM_COMPARATOR","Participants in this arm will undergo an intervention consisting of resistance and aerobic exercises, combined with sham inspiratory muscle training (IMT). The sham IMT protocol will utilize only the minimum load of the device. The protocol will be conducted over 7 weeks, comprising 20 sessions performed 3 times per week.",[19],"Device: Pulmonary rehabilitation with placebo inspiratory muscle training",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Pulmonary rehabilitation combined with inspiratory muscle training","Rehabilitation will begin with diaphragmatic breathing and Inspiratory Muscle Training (IMT) with the Powerbreathe Classic device (3 sets of 10 repetitions, 1 min rest). The initial load will be 50% of PImáx, progressing 10% every 10 sessions until reaching 60%, with monitoring for fatigue and dyspnea.\n\nResistance Training (RT) will utilize lat pulldown, bench press, and leg press on the weight training station. The load is based on the 1RM test, starting at 60% and progressing to 70% after 10 sessions. Aerobic Training (AT) will take place on a stationary bike for 20 min (5 min warm-up and 15 min workout). To calculate the Training Heart Rate (THR), the Karvonen formula will be used: THR = (HRmax - HRrest) x % target intensity + HRrest, followed by the calculation of the Maximum Heart Rate (HRmax) using the Tanaka formula: HRmax = 208 - (0.7 x age). The target intensity will be set between moderate (60% - 70%) and high (70% - 80%).",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Pulmonary rehabilitation with placebo inspiratory muscle training","Pulmonary rehabilitation will consist of resistance and aerobic training protocols with the same specifications as the TMI Group. The placebo TMI will be performed on the Powerbreathe device with minimal load, consisting of 3 sets of 10 repetitions interspersed with 1 minute of rest.",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Gleidiane L. S. Santos","CONTACT","55+ (91) 991023889","gleidianesales05@gmail.com",[38],{"facility":39,"status":26,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Teaching and Assistance Unit in Physiotherapy and Occupational Therapy","Belém","Pará","66093605","Brazil","BR",{"type":46,"coordinates":47},"Point",[48,49],-48.50444,-1.45583,{"lat":49,"lon":48},[52],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Gleidiane Lorrana Sales Dos Santos","Master's Student","100624908","functional-assessment-and-pulmonary-rehabilitation-challenges-and-perspectives-for-comprehensive-care-100624908",false,"NCT07415746","Functional Assessment and Pulmonary Rehabilitation: Challenges and Perspectives for Comprehensive Care","Inclusion Criteria:\n\n* Age 40 years or older.\n* Both sexes are eligible (men and women).\n* Clinically diagnosed COPD, clinically stable, classified in Stages I, II, III or IV of GOLD (Global Initiative for Chronic Obstructive Lung Disease).\n* Ability to understand and provide the signed Informed Consent Form to participate in the study.\n\nExclusion Criteria:\n\n* Physical limitations and\u002For cognitive impairment that prevent the execution of the study protocol.\n* Currently engaged in physical therapy treatment and\u002For physical activity that may interfere with the study results.\n* Presence of severe, uncontrolled, or disabling comorbidities.","ALL","40 Years",{"count":66,"type":67},46,"ESTIMATED","INTERVENTIONAL",[70],"NA","Individuals with Chronic Obstructive Pulmonary Disease (COPD) present with respiratory muscle dysfunction, characterized by reduced diaphragmatic contractility and mobility due to pulmonary hyperinflation, oxidative stress, and systemic inflammation. Effective assessment of diaphragmatic function is crucial for monitoring progress in pulmonary rehabilitation programs. This study aims to evaluate diaphragmatic function and mobility in COPD patients undergoing pulmonary rehabilitation with inspiratory muscle training, using ultrasound, and to identify associations between diaphragmatic dysfunction and clinical symptoms such as dyspnea and fatigue. A randomized clinical trial will be conducted to investigate the impact of rehabilitation on diaphragmatic function, correlating it with pulmonary function and physical performance.",[73],"Pulmonary Disease, Chronic Obstructive",[73,75,76,77],"Rehabilitation","Ultrasonography","Breathing Exercises","NOT_YET_RECRUITING","2026-02-09",{"date":81,"type":82},"2026-02-17","ACTUAL",{"date":84,"type":67},"2026-03",{"date":86,"type":67},"2026-10",{"name":5,"class":6},1]