[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100581663":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":18,"locations":28,"responsibleParty":67,"collaborators":71,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":82,"sex":83,"minAge":84,"maxAge":10,"enrollmentInfo":85,"targetDuration":10,"studyType":88,"phases":10,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"University of Kentucky","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"Healthy",null,"Community-dwelling older adults (≥60 years) with no recent hospitalization",{"label":13,"type":10,"description":14,"interventionNames":10},"ICU Survivor","Patients who survived ICU admission for ARF or sepsis in the last year",{"label":16,"type":10,"description":17,"interventionNames":10},"Chronic Pulmonary Disease","Community-dwelling adults with diagnosis of COPD, ILD, or PF",[19,24],{"name":20,"role":21,"phone":22,"phoneExt":10,"email":23},"Research Associate Senior","CONTACT","859-323-5438","delong2@uky.edu",{"name":25,"role":21,"phone":26,"phoneExt":10,"email":27},"Primary Investigator","859-218-0596","kpmaye2@uky.edu",[29,51],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Florida Atlantic University","RECRUITING","Boca Raton","Florida","33431","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-80.0831,26.35869,{"lat":41,"lon":40},[44,48],{"name":45,"role":21,"phone":46,"phoneExt":10,"email":47},"Principal Investigator","(561) 297-2938","aartese@fau.edu",{"name":49,"role":50,"phone":10,"phoneExt":10,"email":10},"Ashley Artese, PhD","PRINCIPAL_INVESTIGATOR",{"facility":52,"status":31,"city":53,"state":54,"zip":55,"country":35,"countryCode":36,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"Duke University","Durham","North Carolina","27708",{"type":38,"coordinates":57},[58,59],-78.89862,35.99403,{"lat":59,"lon":58},[62,65],{"name":45,"role":21,"phone":63,"phoneExt":10,"email":64},"919-681-3595","amy.pastva@duke.edu",{"name":66,"role":50,"phone":10,"phoneExt":10,"email":10},"Amy Pastva, PT, MA, PhD",{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Kirby Mayer","Associate Professor",[72,73],{"name":52,"class":6},{"name":30,"class":6},"100581663","functional-incremental-stepping-in-place-test-f-ist-validation-100581663",false,"NCT06853236","Functional Incremental Stepping in Place Test (F-IST) Validation","A Cardiorespiratory Fitness Test for Acute Illness: Validity, Reliability, and Clinical Utility of Functional Incremental Stepping-in-Place Test","F-IST","Inclusion Criteria:\n\n-Currently able to walk with or without a walking aid, such as a cane or walker or rollator\n\nExclusion Criteria:\n\nPregnancy\n\nspecifically related to cardiopulmonary testing\n\n* A recent significant change in resting ECG\n* Unstable angina\n* Uncontrolled cardiac dysrhythmias causing symptoms or hemodynamic compromise\n* Symptomatic severe aortic stenosis\n* Uncontrolled symptomatic heart failure\n* Acute pulmonary embolus or pulmonary infarction\n* Acute myocarditis or pericarditis\n* Suspected or known dissecting aneurysm\n* Acute systemic infection accompanied by fever, body aches, or swollen lymph glands\n* Left Main Coronary Stenosis\n* Moderate stenotic valvular heart disease\n* Electrolyte abnormalities\n* Severe arterial hypertension (\\>200 systolic, \\>110 diastolic) at rest\n* Tachydysrhythmia or bradydysrhythmia\n* Hypertrophic cardiomyopathy and other forms of outflow tract obstruction\n* Neuromuscular, musculoskeletal, or rheumatic disorders that are exacerbated by exercise\n* High degree AV block\n* Ventricular aneurysm\n* Uncontrolled metabolic disease (diabetes, thyrotoxicosis, or myxedema)\n* Chronic infectious disease (hepatitis, AIDS, mono)\n* Mental or physical impairment leading to inability to exercise adequately",true,"ALL","18 Years",{"count":86,"type":87},60,"ESTIMATED","OBSERVATIONAL","The purpose of this multi-site prospective study is to assess validity of a new step test called Functional-Incremental Stepping-in-place- Test (F-IST) compared to gold-standard cardiopulmonary exercise testing (CPET) and to physical function and health perception, respectively. The investigators will also assess test-retest reliability of the F-IST. The investigators hypothesize that the F-IST will have high validity and test-retest reliability to be used in field testing environments such as the ICU.",[91,92],"Intensive Care Medicine","Acute Care Medical",[94,95,96,97,98,99],"Cardio respiratory fitness","incremental step test","validity","reliability","physical function","graded exercise testing","2026-03-16",{"date":102,"type":103},"2026-03-17","ACTUAL",{"date":105,"type":103},"2024-07-02",{"date":107,"type":87},"2026-07-02",{"name":69,"class":6},2]