[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644834":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":35,"collaborators":10,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":41,"sex":47,"minAge":48,"maxAge":10,"enrollmentInfo":49,"targetDuration":10,"studyType":52,"phases":10,"briefSummary":53,"conditions":54,"keywords":59,"overallStatus":21,"whyStopped":10,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Kanuni Sultan Suleyman Training and Research Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Adults Undergoing Bone Mineral Density Evaluation",null,"Adult patients attending the Physical Medicine and Rehabilitation outpatient clinic and undergoing routine DXA assessment as part of clinical evaluation. Participants will undergo handgrip strength measurement and assessment of bone mineral density parameters. The Functional Muscle-Bone Incongruity Index (FKUI) will be evaluated using handgrip strength, total hip bone mineral density, and lumbar-hip bone mineral density discordance. No treatment or interventional procedure will be administered.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Dilek Ün Oğuzhanasiltürk, MD","CONTACT","+90 5056367184","dilekunoguzhan@gmail.com",[19],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":10,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey","RECRUITING","Küçükçekmece","Istanbul","34303","Turkey (Türkiye)",{"type":27,"coordinates":28},"Point",[29,30],28.77123,40.99104,{"lat":30,"lon":29},[33],{"name":14,"role":15,"phone":34,"phoneExt":10,"email":17},"+905056367184",{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dilek ün oguzhanasilturk","Physical Medicine and Rehabilitation Specialist","100644834","functional-muscle-bone-incongruity-index-fkui-a-prospective-observational-study-100644834",false,"NCT07677033","Functional Muscle-Bone Incongruity Index (FKUI): A Prospective Observational Study","Functional Muscle-Bone Incongruity Index (FKUI): Combined Evaluation of Handgrip Strength, Total Hip Bone Mineral Density, and Lumbar-Hip Bone Mineral Density Discordance in Adults Undergoing DXA","FKUI","Inclusion Criteria:\n\n* Age 18 years or older\n* Attendance at the Physical Medicine and Rehabilitation outpatient clinic\n* Scheduled to undergo routine bone mineral density assessment by DXA as part of clinical evaluation\n* Ability to perform handgrip strength testing\n* Availability of lumbar spine and total hip bone mineral density measurements suitable for analysis\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\nExclusion Criteria:\n\n* Age younger than 18 years\n* Secondary causes of osteoporosis (e.g., hyperparathyroidism, Cushing syndrome, malignancy, or other conditions affecting bone metabolism)\n* History of metabolic bone disease\n* Major trauma or fracture within the previous 6 months\n* Upper extremity disorders that may significantly affect handgrip strength measurement (e.g., severe osteoarthritis, neurological disorders, major deformities)\n* DXA measurements that are technically inadequate or unsuitable for analysis\n* Refusal or inability to provide written informed consent","ALL","18 Years",{"count":50,"type":51},200,"ESTIMATED","OBSERVATIONAL","The Functional Muscle-Bone Incongruity Index (FKUI) is a novel approach developed to evaluate the relationship between muscle function and bone health. This prospective observational study aims to investigate the clinical applicability of FKUI, which combines handgrip strength, total hip bone mineral density (BMD), and lumbar-hip BMD discordance. Approximately 200 adult participants undergoing routine DXA assessment will be enrolled. The study will examine whether the combined evaluation of muscle function and bone health parameters provides a more comprehensive assessment of musculoskeletal status than individual measures alone.",[55,56,57,58],"Osteoporosis","Musculoskeletal Health","Sarcopenia","Osteopenia",[60,45,61,62,63],"Functional Muscle-Bone Incongruity Index FKUI","Bone Mineral Density","Hip-Spine Discordance","Handgrip Strength","2026-06-24",{"date":66,"type":67},"2026-06-30","ACTUAL",{"date":69,"type":67},"2026-05-01",{"date":71,"type":51},"2027-05-01",{"name":5,"class":6},1]