[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100553214":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":39,"responsibleParty":57,"collaborators":59,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":67,"sex":73,"minAge":74,"maxAge":75,"enrollmentInfo":76,"targetDuration":11,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":11,"overallStatus":86,"whyStopped":11,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Belfast Health and Social Care Trust","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Attune","EXPERIMENTAL",null,[13],"Device: Attune knee implant",{"label":15,"type":16,"description":11,"interventionNames":17},"Triathlon","ACTIVE_COMPARATOR",[18],"Device: Triathlon knee implant",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","Attune knee implant","Attune cementless cruciate retaining rotating platform implant (DePuy Synthes) with a standard gap balancing cruciate sacrificing surgical technique",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Triathlon knee implant","Triathlon cementless condylar stabilised implant (Stryker) with a standard gap balancing cruciate sacrificing surgical technique",[15],[30],{"name":31,"affiliation":5,"role":32},"Richard Napier","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},"Nicola Gallagher","CONTACT","02895043746","nicola.gallagher@belfasttrust.hscni.net",[40],{"facility":41,"status":11,"city":42,"state":11,"zip":11,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Musgrave Park Hospital","Belfast","United Kingdom","UK",{"type":46,"coordinates":47},"Point",[48,49],-5.92541,54.59682,{"lat":49,"lon":48},[52,53],{"name":35,"role":36,"phone":37,"phoneExt":11,"email":38},{"name":54,"role":36,"phone":55,"phoneExt":11,"email":56},"Janet Hill","02895046799","janet.hill@belfasttrust.hscni.net",{"type":58,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR",[60,62],{"name":61,"class":6},"Imperial College London",{"name":63,"class":64},"Trauma and Orthopaedics Research Charity","UNKNOWN","100553214","gait-in-fixed-or-rotating-cementless-total-knee-arthroplasties-100553214",false,"NCT06483178","Gait in Fixed Or Rotating Cementless Total Knee Arthroplasties","A Randomised Controlled Trial Comparing Gait in Fixed or Rotating Cementless Total Knee Arthroplasties","G-FORCE","Inclusion Criteria:\n\n* Patients aged \\\u003C65 years old who require a primary TKA for medial compartment osteoarthritis with a varus deformity.\n* On examination patients must have a pain free ROM of both hips, both ankles and the opposite knee. A history of mild pain in any of these lower limb joints that does not inhibit mobility is acceptable.\n* Must be able to walk at a pre-operative speed of at least 4 km\u002Fh (approximately 30 metres in 30 seconds).\n* Must be able to walk outside unaided or with no more than a walking stick.\n* Must be able to complete pre- and post-operative gait analysis.\n* Participants must have a functional level of spoken and written English and must have a smartphone or have access to a smartphone to complete the online questionnaires on REDCap and to take photographs for virtual assessment of ROM.\n\nExclusion Criteria:\n\n* Patients with valgus deformity of the knee.\n* Patients with previous lower limb arthroplasty.\n* Patients with previous lower limb open reduction and internal fixation (ORIF).\n* Patients who are American Society of Anaesthesiologists (ASA) grade 3 or higher.\n* Patients who are unable to adhere to the trial protocol (due to cognitive impairment, cannot speak English or for any other reason).","ALL","18 Years","65 Years",{"count":77,"type":78},90,"ESTIMATED","INTERVENTIONAL",[81],"NA","The number of patients requiring knee replacements is increasing every year due to the combination of an aging population, increased patient expectancy, and rising levels of obesity. Therefore, newer implants, or design features, are introduced on a regular basis to try to improve patient outcomes. In 2013, DePuy Synthes launched the Attune Knee System to provide improved range of motion and address the unstable feeling some patients experience whilst performing everyday activities, such as going down stairs. The Attune cementless rotating platform knee was first implanted in September 2016. In 2004, the first Triathlon total knee designed by Stryker was implanted. Registry figures for both the Attune and Triathlon knees are promising with good implant longevity and outcomes.\n\nThere is only a small amount of literature available on the Attune knee as it is still a relatively new implant. Worldwide, the Triathlon is widely used and is also a well-established, successful implant used in the investigators' unit. This study will help to determine whether the Attune can improve patient outcomes in terms of gait analysis assessed by walking on a treadmill, patient reported outcome measures and X-ray outcomes when compared to the Triathlon knee. 90 patients who will undergo knee replacement and meet the inclusion criteria and agree to take part will be randomly placed in one of two groups to receive either the Attune or Triathlon knee implant.",[84,85],"Total Knee Arthroplasty","Knee Osteoarthritis","NOT_YET_RECRUITING","2025-05-08",{"date":89,"type":90},"2025-05-13","ACTUAL",{"date":92,"type":78},"2025-05",{"date":94,"type":78},"2027-12",{"name":5,"class":6},1]