[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100504462":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":59,"collaborators":61,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":66,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":88,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of North Carolina, Chapel Hill","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Real-time gait biofeedback (RTGBF)","ACTIVE_COMPARATOR","The RTGBF regimen delivers biofeedback that cues a personalized target to normalize vertical ground reaction force (vGRF) of each limb.",[13],"Behavioral: Real-time gait biofeedback",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham real-time gait biofeedback (Sham RTGBF)","SHAM_COMPARATOR","The Sham RTGBF regimen will receive biofeedback that cues their habitual step length determined during the accommodation period on the first session of treadmill walking.",[19],"Behavioral: Sham real-time gait biofeedback",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Real-time gait biofeedback","The RTGBF interventions will include eighteen step gait training sessions. The intervention will gradually increase to 3,000 steps at the 5th session with 100% feedback. During the remaining sessions, the intervention will include 3,000 steps, but the feedback will be gradually tapered off starting with the 11th session.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham real-time gait biofeedback","The Sham RTGBF interventions will include eighteen step gait training sessions. The intervention will gradually increase to 3,000 steps at the 5th session with 100% feedback. During the remaining sessions, the intervention will include 3,000 steps, but the feedback will be gradually tapered off starting with the 11th session.",[15],[32],{"name":33,"affiliation":5,"role":34},"Brian Pietrosimone, PhD","PRINCIPAL_INVESTIGATOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Natalia Favoreto, MS","CONTACT","9199622025","favoreto@med.unc.edu",{"name":33,"role":38,"phone":42,"phoneExt":26,"email":43},"19199623617","pietrosi@email.unc.edu",[45],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":26},"University of North Carolina at Chapel Hill","RECRUITING","Chapel Hill","North Carolina","27516","United States","US",{"type":54,"coordinates":55},"Point",[56,57],-79.05584,35.9132,{"lat":57,"lon":56},{"type":60,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[62],{"name":63,"class":6},"Arthritis Foundation","100504462","gait-rehabilitation-to-treat-fastoa-100504462",false,"NCT05848622","Gait Rehabilitation to Treat FastOA","Inclusion Criteria:\n\n* Have completed all other formal physical therapy\n* Are between the ages of 16 and 35\n* Underwent an anterior cruciate ligament reconstruction (ACLR) between 6 and 60 months prior to enrollment\n* Demonstrate underloading during gait (vGRF- impact peak \\\u003C1.12 x BW)\n\nExclusion Criteria:\n\n* A multiple ligament surgery (i.e., PCL)\n* A lower extremity fracture (i.e., displaced tibial plateau fracture)\n* Knee osteoarthritis","ALL","16 Years","35 Years",{"count":74,"type":75},70,"ESTIMATED","INTERVENTIONAL",[78],"NA","The purpose of this study is to determine the effects of real-time gait biofeedback delivered over a 6-week period on early markers of FastOA and conduct 6-week and 6-month follow-up assessments in anterior cruciate ligament reconstructed patients.",[81,82,83,84,85,86,87],"Anterior Cruciate Ligament Injuries","Post-traumatic Osteoarthritis","Knee Osteoarthritis","Osteo Arthritis Knee","Knee Injuries","Cartilage, Articular","Gait",[89,90],"Biofeedback","FastOA","2026-06-24",{"date":93,"type":94},"2026-06-25","ACTUAL",{"date":96,"type":94},"2023-06-13",{"date":98,"type":75},"2027-06",{"name":5,"class":6},1]