[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100631179":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":18,"responsibleParty":36,"collaborators":10,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":42,"sex":48,"minAge":49,"maxAge":10,"enrollmentInfo":50,"targetDuration":10,"studyType":53,"phases":10,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":21,"whyStopped":10,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},{"fullName":5,"class":6},"Akdeniz University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients Undergoing LVAD Implantation",null,"Patients with advanced heart failure undergoing left ventricular assist device (LVAD) implantation whose preoperative GDF-15 levels will be evaluated in relation to early postoperative outcomes and mortality.",[13],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"emel gündüz, md","CONTACT","+902422496000","dregunduz@hotmail.com",[19],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":10,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"Akdeniz University, Faculty of Medicine, Department of Anesthesiology and Reanimation","RECRUITING","Antalya","Please Select:","07050","Turkey (Türkiye)",{"type":27,"coordinates":28},"Point",[29,30],30.69556,36.90812,{"lat":30,"lon":29},[33],{"name":34,"role":15,"phone":35,"phoneExt":10,"email":17},"emel gündüz","02422496000",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Emel Gunduz","Associate Professor of Anesthesiology, Akdeniz University, Antalya, Turkey","100631179","gdf-15-and-early-outcomes-after-lvad-implantation-100631179",false,"NCT07497308","GDF-15 and Early Outcomes After LVAD Implantation","Association of Preoperative GDF-15 Levels With Early Postoperative Outcomes and Mortality After LVAD Implantation","LVAD-GDF15","Inclusion Criteria:Adults aged 18 years and older\n\nPatients with advanced heart failure undergoing LVAD implantation\n\nAvailability of preoperative GDF-15 measurement\n\nAbility to provide written informed consent or consent provided by a legally authorized representative, according to local regulations -\n\nExclusion Criteria:Age under 18 years\n\nActive infection\n\nActive malignancy\n\nSevere hepatic failure\n\nMissing study data\n\nRefusal to participate\n\n\\-","ALL","18 Years",{"count":51,"type":52},48,"ESTIMATED","OBSERVATIONAL","This observational study aims to investigate the association between preoperative GDF-15 levels and early postoperative outcomes in patients undergoing left ventricular assist device (LVAD) implantation. The study will evaluate whether elevated preoperative GDF-15 levels are associated with adverse early outcomes, including postoperative complications and mortality. The findings may help improve preoperative risk assessment and identify high-risk patients before LVAD implantation.",[56,57],"Advanced Heart Failure","Left Ventricular Assist Device Implantation",[59,60,61,62],"Left Ventricular Assist Device","GDF-15","Postoperative Outcomes","Early Mortality","2026-03-24",{"date":65,"type":66},"2026-03-27","ACTUAL",{"date":68,"type":66},"2026-02-04",{"date":70,"type":52},"2026-12-23",{"name":5,"class":6},1]