[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100529587":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":11,"centralContacts":11,"locations":23,"responsibleParty":42,"collaborators":11,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":46,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":11,"studyType":58,"phases":59,"briefSummary":61,"conditions":62,"keywords":11,"overallStatus":26,"whyStopped":11,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Pirogov Russian National Research Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Regional anesthesia for carotid endarterectomy in patients with acute stage of ischemic stroke.","ACTIVE_COMPARATOR",null,[13],"Procedure: carotid endarterectomy",{"label":15,"type":10,"description":11,"interventionNames":16},"General anesthesia for carotid endarterectomy in patients with acute stage of ischemic stroke.",[13],[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":11},"PROCEDURE","carotid endarterectomy","carotid endarterectomy under local or general anethesia",[15,9],[24],{"facility":25,"status":26,"city":27,"state":11,"zip":11,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Pryamikov Aleksandr","RECRUITING","Moscow","Russia","RU",{"type":31,"coordinates":32},"Point",[33,34],37.61781,55.75204,{"lat":34,"lon":33},[37],{"name":38,"role":39,"phone":40,"phoneExt":11,"email":41},"Aleksandr Pryamikov","CONTACT","89032862552","pryamikov80@rambler.ru",{"type":43,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100529587","general-versus-regional-anesthesia-for-carotid-endarterectomy-at-acute-ischemic-stroke-trial-100529587",false,"NCT06175715","General Versus Regional Anesthesia for Carotid Endarterectomy at Acute Ischemic Stroke Trial","The Study is Planned to Evaluate the Effectiveness and Safety of Two Types of Anesthesia (Regional and General) for Carotid Endarterectomy in 100 Patients With Acute Stage of Stroke: 50 Patients Will be Operated Under Regional Anesthesia and the Remaining 50 Patients Under General Anesthesia.","GRACE AIST","Inclusion Criteria:\n\n* 1\\. Ischemic stroke in the middle cerebral artery territory 2. Ipsilateral stenosis of the internal carotid artery more than 50% 3. Neurological deficit at the time of surgical treatment: the modified Rankin scale (mRs) score of 0-4 and the US National Institutes of Health (NIHSS) stroke scale score no more than 12 4. The size of the ischemia focus: no more than 1\u002F3 in the territory of the middle cerebral artery brain supply 5. Terms of operation: from 1 to 28 days from the moment of ischemic stroke\n\nExclusion Criteria:\n\n\\-","ALL","40 Years","80 Years",{"count":56,"type":57},100,"ESTIMATED","INTERVENTIONAL",[60],"NA","The study is planned to evaluate the effectiveness and safety of two types of anesthesia (regional and general) for carotid endarterectomy in 100 patients with acute stage of stroke: 50 patients will be operated under regional anesthesia and the remaining 50 patients under general anesthesia.\n\nPatient inclusion criteria:\n\n1. Ischemic stroke in the middle cerebral artery territory\n2. Ipsilateral stenosis of the internal carotid artery more than 50%\n3. Neurological deficit at the time of surgical treatment: the modified Rankin scale (mRs) score of 0-4 and the US National Institutes of Health (NIHSS) stroke scale score no more than 12\n4. The size of the ischemia focus: no more than 1\u002F3 in the territory of the middle cerebral artery brain supply\n5. Terms of operation: from 1 to 28 days from the moment of ischemic stroke\n\nThe primary intra-hospital and\u002For 30-day study endpoints:\n\n1. Perioperative ipsilateral ischemic stroke.\n2. Any stroke: contralateral ischemic or any hemorrhagic stroke.\n3. Myocardial infarction.\n4. Hemorrhagic complications that required surgical revision of the operating wound or transfusion of blood components.\n5. Surgical site infection\n6. Death\n7. Main adverse cardiovascular events (stroke + myocardial infarction + death).",[63],"Acute Ischemic Stroke","2026-03-23",{"date":66,"type":67},"2026-03-27","ACTUAL",{"date":69,"type":67},"2024-07-01",{"date":71,"type":57},"2028-12-31",{"name":5,"class":6},1]