[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100573531":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":32,"locations":40,"responsibleParty":57,"collaborators":24,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":24,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":24,"enrollmentInfo":69,"targetDuration":24,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":87,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"University of Miami","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"General Anesthesia","EXPERIMENTAL","Participants in this group will receive general anesthesia for TJA for up to 2 hours.",[13],"Procedure: General Anesthesia",{"label":15,"type":10,"description":16,"interventionNames":17},"Spinal Anesthesia","Participants in this group will receive spinal anesthesia for TJA for up to 2 hours.",[18],"Procedure: Spinal Anesthesia",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"PROCEDURE","Participants will receive a one-time general anesthesia dose during the total joint arthroplasty procedure as per standard of care.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Participants will receive a one-time spinal anesthesia dose during the total joint arthroplasty procedure as per standard of care.",[15],[29],{"name":30,"affiliation":5,"role":31},"Victor H Hernandez, MD","PRINCIPAL_INVESTIGATOR",[33,37],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},"CONTACT","305-689-5195","vhh1@med.miami.edu",{"name":38,"role":34,"phone":35,"phoneExt":24,"email":39},"Antonio M Fernandez-Perez, MS","axf2089@miami.edu",[41],{"facility":5,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Miami","Florida","33136","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-80.19366,25.77427,{"lat":52,"lon":51},[55,56],{"name":30,"role":34,"phone":35,"phoneExt":24,"email":36},{"name":30,"role":31,"phone":24,"phoneExt":24,"email":24},{"type":31,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Victor Hugo Hernandez","Professor of Clinical","100573531","general-vs-spinal-in-total-joint-arthroplasty-tja-100573531",false,"NCT06747494","General vs Spinal in Total Joint Arthroplasty (TJA)","General Versus Spinal Anesthesia for Total Joint Arthroplasty: A Prospective Randomized Trial","Inclusion Criteria:\n\n* Patients undergoing a primary total hip or knee arthroplasty\n* Subjects must be capable of providing informed consent\n* English or Spanish speaking\n\nExclusion Criteria:\n\nPatients with contraindications for spinal anesthesia such as:\n\n* Prior lumbar surgery with hardware insertion\n* Elevated intracranial pressure\n* Infection at the site of the procedure\n* Thrombocytopenia or coagulopathy\n* Severe mitral and aortic stenosis and left ventricular outflow obstruction\n* Severe spine pathology (spinal stenosis, spondylolisthesis, spondylosis) with radiculopathy and\u002For neurogenic claudication\n* Preexisting neurological disease\n\nPatients with contraindications for general anesthesia such as:\n\n* Congestive heart failure\n* Severe aortic stenosis\n* Patient is unable\u002Funwilling to consent\n* Current pregnancy or women planning on becoming pregnant in the next year, and women who think they might be pregnant, or women who become pregnant during the study period will be removed from the study.\n* Prisoners","ALL","18 Years",{"count":70,"type":71},2396,"ESTIMATED","INTERVENTIONAL",[74],"NA","The purpose of this research is to compare post-operative outcomes from patients undergoing TJA. The study team wants to learn about outcomes like length of hospital stay, post-operative pain scores, post-operative nausea, deep and superficial surgical site infection, periprosthetic fracture (a broken bone that occurs around an orthopaedic implant), implant dislocation, readmission rates, and revision rates.",[77,78],"Knee Osteoarthritis","Hip Osteoarthritis",[80,81,82],"Total joint arthroplasty","General anesthesia","Spinal anesthesia","2026-03-17",{"date":85,"type":86},"2026-03-18","ACTUAL",{"date":88,"type":86},"2025-02-01",{"date":90,"type":71},"2030-03-01",{"name":5,"class":6},1]