[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612792":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":26,"responsibleParty":42,"collaborators":44,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":49,"sex":55,"minAge":56,"maxAge":10,"enrollmentInfo":57,"targetDuration":10,"studyType":60,"phases":10,"briefSummary":61,"conditions":62,"keywords":10,"overallStatus":29,"whyStopped":10,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Regina Elena Cancer Institute","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients with endometrial cancer of the endometrioid histology at any stage of the disease.",null,"Patients aged 18 years and older with a histological diagnosis of endometrial cancer of the endometrioid histology at any stage of disease (FIGO I-IV), recurrence\u002Fmetastasis from endometrial endometrioid cancer, who are candidates for surgery or hysterectomy and who will undergo surgery after signing an informed consent form, will be prospectively recruited.",[13],"Genetic: Generation of organoids from endometrial tumor tissue collected during surgery, performed according to standard clinical practice",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"GENETIC","Generation of organoids from endometrial tumor tissue collected during surgery, performed according to standard clinical practice","Creation of endometrial carcinoma organoids from tumor tissue from extramural structures, verifying the feasibility of organoid generation. Evaluate the impact of sample transport and storage conditions on the success of the process, considering the challenges associated with preserving tissue integrity.",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Giovanni Blandino, Medical Doctor","CONTACT","+39 0652662911","giovanni.blandino@ifo.it",[27],{"facility":28,"status":29,"city":30,"state":30,"zip":31,"country":32,"countryCode":33,"cosmosGeoPoint":34,"geoPoint":39,"contacts":40},"IRCCS National Cancer Institute \"Regina Elena\"","RECRUITING","Roma","00144","Italy","IT",{"type":35,"coordinates":36},"Point",[37,38],11.10642,44.99364,{"lat":38,"lon":37},[41],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},{"type":43,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[45],{"name":46,"class":6},"Azienda Ospedaliera Universitaria Integrata Verona","100612792","generation-of-endometrial-carcinoma-organoids-100612792",false,"NCT07258186","Generation of Endometrial Carcinoma Organoids","Feasibility Study of the Generation of Endometrial Carcinoma Organoids From Tumor Samples Transferred From Extramural Facilities","organoids endo","Inclusion Criteria:\n\n* Age \\>18 years;\n* Patients with a histological diagnosis of: endometrial cancer, endometrioid histology, any stage of disease (FIGO I-IV), recurrence\u002Fmetastasis from endometrial endometrioid cancer, and candidates for surgery and\u002For hysterectomy;\n* Written informed consent (study participation and data processing) must be obtained in person and\u002For through a legal representative\u002Fguardian\u002Fsupport administrator\u002Fwitness, before any study-specific procedure is performed.\n\nExclusion Criteria:\n\n* Comorbidities not controlled with adequate medical therapy;\n* Endometrial cavity infections (pyometra);\n* Synchronous tumors;\n* Neoadjuvant treatments;\n* Previous radiation treatments to the pelvic region.","FEMALE","18 Years",{"count":58,"type":59},20,"ESTIMATED","OBSERVATIONAL","A prospective pilot genetic study to evaluate the feasibility of generating organoids from endometrial tumor tissue collected during surgery, performed according to standard clinical practice. Samples will be collected from collaborating extramural facilities, with the aim of analyzing the impact of transport on tissue viability and the success of organoid culture. This study is for exploratory purposes only, without altering the diagnostic and therapeutic pathways of the participants.",[63],"Endometrial Cancer","2025-11-27",{"date":66,"type":67},"2025-12-02","ACTUAL",{"date":69,"type":67},"2025-03-23",{"date":71,"type":59},"2028-09-23",{"name":5,"class":6},1]