[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100335553":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":12,"centralContacts":16,"locations":21,"responsibleParty":37,"collaborators":40,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":49,"acronym":7,"eligibilityCriteria":50,"healthyVolunteers":51,"sex":52,"minAge":53,"maxAge":7,"enrollmentInfo":54,"targetDuration":57,"studyType":58,"phases":7,"briefSummary":59,"conditions":60,"keywords":65,"overallStatus":23,"whyStopped":7,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Medical College of Wisconsin","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Blood Collection","Blood will be collected via venipuncture and analyzed. Blood samples will be analyzed for HLA haplotype (a genetic sequence related to type 1 diabetes susceptibility), plasma-induced signature, diabetes autoantibodies, complete blood count with differential, and serum and plasma for storage. For family members with diabetes, blood will also be tested for A1c.",[13],{"name":14,"affiliation":5,"role":15},"Martin Hessner, PhD","PRINCIPAL_INVESTIGATOR",[17],{"name":14,"role":18,"phone":19,"phoneExt":7,"email":20},"CONTACT","414-955-4903","t1dinfo@mcw.edu",[22],{"facility":5,"status":23,"city":24,"state":25,"zip":26,"country":27,"countryCode":28,"cosmosGeoPoint":29,"geoPoint":34,"contacts":35},"RECRUITING","Milwaukee","Wisconsin","53226","United States","US",{"type":30,"coordinates":31},"Point",[32,33],-87.90647,43.0389,{"lat":33,"lon":32},[36],{"name":14,"role":18,"phone":19,"phoneExt":7,"email":20},{"type":15,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Martin Hessner","Professor",[41,43],{"name":42,"class":6},"Benaroya Research Institute",{"name":44,"class":6},"Indiana University","100335553","genetics-of-autoimmunity-in-type-i-diabetes-100335553",false,"NCT03648918","Genetics Of Autoimmunity In Type I Diabetes","Inclusion Criteria (Families):\n\n* Families where at least one first-degree family member has type 1 diabetes\n* The diabetic proband in the family was diagnosed before the age of 39\n* Family members must be at least 2 years old to participate\n\nExclusion Criteria (Families):\n\n* Families with no history of type 1 diabetes\n* Families with a history of diabetes that is not type 1 (LADA, MODY, type 2 etc.)\n\nInclusion Criteria (Controls):\n\n* No family history of type 1 diabetes or other autoimmune conditions\n* Age 2 or older\n\nExclusion Criteria (Controls):\n\n* Personal or family history of autoimmune disease",true,"ALL","2 Years",{"count":55,"type":56},4000,"ESTIMATED","10 Years","OBSERVATIONAL","The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes. Scientists think that a person's own immune system, directed by genetic and environmental factors play a major role in its development. Participation involves a blood draw, a brief medical history questionnaire and measurements of height and weight. Some participants will be asked to return for annual follow-up visits for 10 years.",[61,62,63,64],"Type1diabetes","Diabetes Mellitus, Type 1","Type1 Diabetes Mellitus","Diabetes Mellitus",[66,67,68],"Family","Healthy Controls","Siblings","2026-03-12",{"date":71,"type":72},"2026-03-16","ACTUAL",{"date":74,"type":72},"2001-08",{"date":76,"type":56},"2050-01",{"name":5,"class":6},1]